Proteases
Proteases(蛋白酶)
Proteases, also known as peptidases or proteolytic enzymes, consists of a large number of enzymes catalyzing the hydrolysis of peptide bonds and subsequently resulting in the degradation of protein substrates into amino acids. Proteases are involved in a wide range of human diseases, including cancer, neurodegenerative disorders, inflammatory diseases and cardiovascular diseases. Thus numerous proteases inhibitors (small molecules and proteins) have been identified to block activity of proteases. Proteases inhibitors can be classified into different types based on the class of proteases they inhibit through two general mechanisms, irreversible “trapping” reactions and reversible tight-binding reactions. Proteases inhibitors have been used as diagnostic or therapeutic agents for the treatment of proteases-related diseases.
- Aminopeptidase(21)
- ACE(75)
- Calpains(11)
- Carboxypeptidase(9)
- Cathepsin(65)
- DPP-4(18)
- Elastase(25)
- Gamma Secretase(50)
- HCV Protease(39)
- HSP(105)
- HIV Integrase(30)
- HIV Protease(35)
- MMP(195)
- NS3/4a protease(4)
- Serine Protease(19)
- Thrombin(47)
- Urokinase(2)
- Cysteine Protease
- Tyrosinases(50)
- Other Proteases(15)
- 15-PGDH(1)
- Acetyl-CoA Carboxylase(14)
- Acyltransferase(64)
- Aldehyde Dehydrogenase (ALDH)(30)
- Aminoacyl-tRNA Synthetase(9)
- ATGL(1)
- Dipeptidyl Peptidase(49)
- Drug Metabolite(513)
- E1/E2/E3 Enzyme(92)
- Endogenous Metabolite(1768)
- FABP(9)
- Farnesyl Transferase(20)
- Glutaminase(17)
- Glutathione Peroxidase(35)
- Isocitrate Dehydrogenase (IDH)(28)
- Lactate Dehydrogenase(19)
- Lipoxygenase(274)
- Mitochondrial Metabolism(260)
- NEDD8-activating Enzyme(6)
- Neprilysin(12)
- PAI-1(14)
- Ser/Thr Protease(49)
- Tryptophan Hydroxylase(12)
- Xanthine Oxidase(18)
- MALT1(10)
- Caspase(117)
- PCSK9(13)
- ADAMTS(1)
- Density Lipoprotein
- TrxR(1)
- DGK(3)
Proteases 相关产品(4079)
- GC336104-Hydroxycyclohexanecarboxylic acidCAS: 17419-81-7纯度: >95.00%
4-Hydroxycyclohexanecarboxylicacid属于环己醇有机化合物类。
- GC336153,4-Dimethoxyphenylacetic acidCAS: 93-40-3纯度: >99.00%
Homoveratrumic acid (Homoveratric acid) is the main metabolite of 3,4-dimethoxyphenylethylamine (DMPEA) in urine.
- GC336183-(3,4,5-Trimethoxyphenyl)propanoic acidCAS: 25173-72-2纯度: >97.00%
3-(3,4,5-Trimethoxyphenyl)propanoicacid存在于草药和香料中。3-(3,4,5-Trimethoxyphenyl)propanoicacid是Piperlongum(长胡椒)和Piperretrofractum(爪哇长胡椒)的成分。
- GC336211,2-Dipalmitoyl-sn-glycerol 3-phosphateCAS: 7091-44-3
1,2-Dipalmitoyl-sn-glycerol3-phosphate是一种磷脂酸。
- GC336222',4'-DihydroxyacetophenoneCAS: 89-84-9纯度: >99.50%
2,4-Dihydroxyacetophenone (Resacetophenone, 4-Acetylresorcinol) is a plant metabolite that can act as a qualitative reagent for ferric iron.
- GC336262,4-Dihydroxybenzoic acidCAS: 89-86-1纯度: >99.50%
2,4-Dihydroxybenzoic acid (β-resorcylic acid, p-Hydroxysalicylic acid) is a degradation product of cyanidin glycosides from tart cherries in cell cultures and a metabolite found in human plasma after cranberry juice consumption.
- GC33635N-Methylsarcosine (DMG)CAS: 1118-68-9纯度: >98.00%
N-Methylsarcosine (N,N-Dimethylglycine, (Dimethylamino)acetic acid) is a natural N-methylated glycine that is used in the development of glycine-based ionic liquids and emulsifiers.
- GC336372,5-Furandicarboxylic acidCAS: 3238-40-2纯度: >99.50%
2,5-Furandicarboxylic acid (Dehydromucic acid) is a normal urinary metabolite in humans and an important renewable building block because of its potential as a substitute for a variety of petrochemicals, such as terephthalic acid and adipic acid.
- GC33640Nepsilon-Acetyl-L-lysineCAS: 692-04-6
Nepsilon-Acetyl-L-lysine is an R-chain N-acetylated α amino acid used together with other lysine analogues to differentiate and characterized various aminoacylases and regulator 2 (Sir2) enzymes/sirtuins.
- GC336422,6-Dihydroxybenzoic acidCAS: 303-07-1纯度: >99.50% / >98.00%
2,6-Dihydroxybenzoic acid (γ-resorcylic acid, 2-Carboxyresorcinol, 2,6-Resorcylic acid) is a phenolic compound which is known to have poor biological performance such as DPPH scavenging activity and microbial growth inhibition.
- GC336432,6-Dimethoxybenzoic acidCAS: 1466-76-8
2,6-Dimethoxybenzoic acid is a polyphenol compound found in foods of plant origin.
- GC336452-Guanidinoacetic acidCAS: 352-97-6
A metabolite of glycine and precursor in the biosynthesis of creatine
- GC336461-MethyladenineCAS: 5142-22-3纯度: >99.00% / >98.00%
1-Methyladenine是一种甲基化的腺嘌呤核苷酸，是DNA中烷基化损伤的产物。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC33610 | 4-Hydroxycyclohexanecarboxylic acid | 17419-81-7 | >95.00% | |
4-Hydroxycyclohexanecarboxylicacid属于环己醇有机化合物类。 | ||||
| GC33612 | N-Acetyl-L-aspartic acid | 997-55-7 | >95.00% | |
An acetylated form of L-aspartic acid | ||||
| GC33613 | 5-Hydroxymethyluracil | 4433-40-3 | >98.00% | |
Product of oxidative damage to DNA | ||||
| GC33615 | 3,4-Dimethoxyphenylacetic acid | 93-40-3 | >99.00% | |
Homoveratrumic acid (Homoveratric acid) is the main metabolite of 3,4-dimethoxyphenylethylamine (DMPEA) in urine. | ||||
| GC33616 | 7-Methylguanine | 578-76-7 | - | |
A nucleotide metabolite | ||||
| GC33617 | Hexacosanoic acid | 506-46-7 | >98.00% | |
A 26-carbon saturated fatty acid | ||||
| GC33618 | 3-(3,4,5-Trimethoxyphenyl)propanoic acid | 25173-72-2 | >97.00% | |
3-(3,4,5-Trimethoxyphenyl)propanoicacid存在于草药和香料中。3-(3,4,5-Trimethoxyphenyl)propanoicacid是Piperlongum(长胡椒)和Piperretrofractum(爪哇长胡椒)的成分。 | ||||
| GC33621 | 1,2-Dipalmitoyl-sn-glycerol 3-phosphate | 7091-44-3 | - | |
1,2-Dipalmitoyl-sn-glycerol3-phosphate是一种磷脂酸。 | ||||
| GC33622 | 2',4'-Dihydroxyacetophenone | 89-84-9 | >99.50% | |
2,4-Dihydroxyacetophenone (Resacetophenone, 4-Acetylresorcinol) is a plant metabolite that can act as a qualitative reagent for ferric iron. | ||||
| GC33625 | N8-Acetylspermidine dihydrochloride | 34450-15-2 | >99.50% | |
An endogenous polyamine | ||||
| GC33626 | 2,4-Dihydroxybenzoic acid | 89-86-1 | >99.50% | |
2,4-Dihydroxybenzoic acid (β-resorcylic acid, p-Hydroxysalicylic acid) is a degradation product of cyanidin glycosides from tart cherries in cell cultures and a metabolite found in human plasma after cranberry juice consumption. | ||||
| GC33629 | DPPC (129Y83) | 63-89-8 | >98.00% / >99.00% / >95.00% | |
DPPC (129Y83)是一种磷酸甘油酯，可用于制备脂质体。 | ||||
| GC33630 | Tryptamine | 61-54-1 | >98.00% | |
An indole alkaloid | ||||
| GC33631 | 3-Chloro-L-tyrosine | 7423-93-0 | - | |
A derivative of L-tyrosine | ||||
| GC33633 | 2-(2-Methylbenzamido)acetic acid | 42013-20-7 | >97.00% | |
A metabolite of xylene | ||||
| GC33635 | N-Methylsarcosine (DMG) | 1118-68-9 | >98.00% | |
N-Methylsarcosine (N,N-Dimethylglycine, (Dimethylamino)acetic acid) is a natural N-methylated glycine that is used in the development of glycine-based ionic liquids and emulsifiers. | ||||
| GC33636 | 5'-Deoxyadenosine | 4754-39-6 | >98.00% | |
An adenosine analog | ||||
| GC33637 | 2,5-Furandicarboxylic acid | 3238-40-2 | >99.50% | |
2,5-Furandicarboxylic acid (Dehydromucic acid) is a normal urinary metabolite in humans and an important renewable building block because of its potential as a substitute for a variety of petrochemicals, such as terephthalic acid and adipic acid. | ||||
| GC33640 | Nepsilon-Acetyl-L-lysine | 692-04-6 | - | |
Nepsilon-Acetyl-L-lysine is an R-chain N-acetylated α amino acid used together with other lysine analogues to differentiate and characterized various aminoacylases and regulator 2 (Sir2) enzymes/sirtuins. | ||||
| GC33641 | Hydroxyphenylacetylglycine | 28116-23-6 | - | |
A metabolite of tyramine | ||||
| GC33642 | 2,6-Dihydroxybenzoic acid | 303-07-1 | >99.50% / >98.00% | |
2,6-Dihydroxybenzoic acid (γ-resorcylic acid, 2-Carboxyresorcinol, 2,6-Resorcylic acid) is a phenolic compound which is known to have poor biological performance such as DPPH scavenging activity and microbial growth inhibition. | ||||
| GC33643 | 2,6-Dimethoxybenzoic acid | 1466-76-8 | - | |
2,6-Dimethoxybenzoic acid is a polyphenol compound found in foods of plant origin. | ||||
| GC33645 | 2-Guanidinoacetic acid | 352-97-6 | - | |
A metabolite of glycine and precursor in the biosynthesis of creatine | ||||
| GC33646 | 1-Methyladenine | 5142-22-3 | >99.00% / >98.00% | |
1-Methyladenine是一种甲基化的腺嘌呤核苷酸，是DNA中烷基化损伤的产物。 | ||||