Metabolism

谷氨酰胺酶C抑制剂11是一种谷氨酰胺酶C（GAC）的抑制剂。它能够抑制GAC酶活性（EC50 = 10.64 nM），并降低A549非小细胞肺癌（NSCLC）细胞的存活率（IC50 = 4.025 nM）。

N-乙基全氟辛烷磺酰胺乙醇（N-ethyl FOSE）是一种全氟烷基物质（PFAS）。

Ipamorelin是一种五肽生长激素分泌素（GHS）和GHS受体1a（GHS-R1a）激动剂。

Exendin-4 (3-39)酰胺是一种糖肽样肽1受体（GLP-1R）激动剂，也是exendin-4 (48-86)酰胺的活性代谢物。

Chondroitin sulfate A (CSA) is a glycosaminoglycan.

Propiverine N-oxide is an active metabolite of the muscarinic acetylcholine receptor antagonist propiverine .

Voriconazole-d3 N-oxide is intended for use as an internal standard for the quantification of voriconazole N-oxide by GC- or LC-MS.

(E/Z)-Droloxifene is a mixture of (E)-droloxifene, a selective estrogen receptor modulator (SERM), and (Z)-droloxifene.

Tanzawaic acid B is a fungal metabolite that has been found in Penicillium and has diverse biological activities.

Rosuvastatin EP impurity A is a potential impurity in commercial preparations of the HMG-CoA reductase inhibitor rosuvastatin.

GPX4 16 is an inhibitor of glutathione peroxidase 4 (GPX4).

FerroLOXIN-1 is an inhibitor of the 15-lipoxygenase-2 (15-LO-2) and phosphatidylethanolamine-binding protein 1 (PEBP1) catalytic complex.

Ferroptosis inducer 24 is an inducer of ferroptosis.

NSC 44625 is an inhibitor of carbonic anhydrase II (CAII; Ki = 63 nM for the human enzyme).

TASP0277308 is a sphingosine-1-phosphate receptor 1 (S1P1) antagonist (IC50 = 4.2 nM).

viFSP1 is a species-independent inhibitor of ferroptosis suppressor protein 1 (FSP1; IC50s = 34 and 83 nM for the human and mouse enzymes, respectively).

Etomidate-d5 is intended for use as an internal standard for the quantification of etomidate by GC- or LC-MS.

ABBV-CLS-484 is a dual inhibitor of protein tyrosine phosphatase 1N (PTP1N) and PTP2N (IC50s = 2.5 and 1.8 nM, respectively).

ENPP3 inhibitor 5J is an inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1) and ENPP3 (IC50s = 0.59 and 0.62 µM, respectively, for the human enzymes).

GSK205 is an inhibitor of transient receptor potential vanilloid 4 (TRPV4) and transient receptor potential ankyrin 1 (TRPA1; IC50s = 4.19 and 5.56 µM, respectively, for the rat channels).

18-hydroxy Oleoyl leucine-d7 is intended for use as an internal standard for the quantification of 18-hydroxy oleoyl leucine by GC- or LC-MS.

h-e5'NT Inhibitor 5C is an inhibitor of ecto-5'-nucleotidase, also known as CD73 (IC50s = 0.37 and 1.66 µM for the human and rat enzymes, respectively).

FA16 is a ferroptosis inducer and an inhibitor of the system xc- cystine/glutamate transporter.

Cholic acid 3-sulfate is a metabolite of the primary bile acid cholic acid .