Transferase
Transferase(转移酶)
Transferases are a collection of a large and diverse group of enzymes that specifically catalyze the transfer of one or more functional groups from one molecule (the donor) to another (the acceptor). A few transferases involved in this category include farnesyltransferase (FTase), diacylglycerol acyltransferase (DGAT) and catechol-O-methyltransferase (COMT). Ftase catalyzes the transfer of a farnesyl moiety to the cysteine terminal residue (the sulfhydryl cysteine of the CAAS motif)) of substrate proteins. DGAT catalyzes the final step of the triacylglycerol (TG) biosynthetic pathway, where diacylglycerol is esterified to produce TG. COMT catalyzes the methylation of catechol substrates utilizing S-adenosyl-L-methionine (SAM) as a methyl donor and generating O-methylated catechol and S-adenosyl-L-homocysteine.
Transferase 相关产品(26)
- GC15274PF-04620110CAS: 1109276-89-2纯度: >99.00% / >98.00%
PF-04620110是一种口服有效的选择性二酰甘油酰基转移酶-1（DGAT1）抑制剂（IC 50 = 19nM）。
- GC10905Amodiaquine dihydrochloride dihydrateCAS: 6398-98-7纯度: >99.50%
A prodrug form of N-desethyl amodiaquine
- GC15442Tipifarnib (Zarnestra)CAS: 192185-72-1纯度: >98.50%
A farnesyltransferase inhibitor with antitumor activity
- GC16310FTI 277 HClCAS: 180977-34-8纯度: >99.00%
FTI 277 HCl是一种强效且具有选择性的法尼基转移酶（FTase）抑制剂，IC 50 值为0.5nM，较香叶酰基香叶转移酶I（GGTase I）选择性高出约100倍。
- GC16738Tunicamycin MixtureCAS: 11089-65-9纯度: >95.00%
Tunicamycin Mixture是一种同源核苷抗生素的混合物, 可抑制N-糖基化并阻断GlcNAc 磷酸转移酶（GPT）。
- GP26139CHST3 Human
CHST3 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 450 amino acids (39-479
- GP26140CHST5 Human
CHST5 Human produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 380 amino acids (27-395 a
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC10330 | Lonafarnib | 193275-84-2 | >98.50% | |
A farnesyltransferase inhibitor with antitumor activity | ||||
| GC14308 | FK866 (APO866) | 658084-64-1 | >99.50% | |
Inhibitor of nicotinamide phosphoribosyltransferase | ||||
| GC15274 | PF-04620110 | 1109276-89-2 | >99.00% / >98.00% | |
PF-04620110是一种口服有效的选择性二酰甘油酰基转移酶-1（DGAT1）抑制剂（IC 50 = 19nM）。 | ||||
| GC15614 | A922500 | 959122-11-3 | >98.50% | |
A922500是一种有效、选择性高且具有口服活性的二酰基甘油酰基转移酶1（DGAT-1）抑制剂，对人源和小鼠DGAT-1的IC 50 值分别为9和22nM。 | ||||
| GC17921 | Tolcapone | 134308-13-7 | - | |
A reversible COMT inhibitor | ||||
| GC10106 | OR-486 | 7659-29-2 | - | |
A potent COMT inhibitor | ||||
| GC10265 | Manumycin A | 52665-74-4 | >98.00% | |
A farnesyltransferase inhibitor with antitumor activity | ||||
| GC10905 | Amodiaquine dihydrochloride dihydrate | 6398-98-7 | >99.50% | |
A prodrug form of N-desethyl amodiaquine | ||||
| GC11524 | Cystamine dihydrochloride | 56-17-7 | - | |
An inhibitor of tissue transglutaminase | ||||
| GC11884 | GPP 78 hydrochloride | - | - | |
Inhibitor of Nampt | ||||
| GC12449 | SKF 91488 dihydrochloride | 68941-21-9 | - | |
histamine N-methyltransferase inhibitor | ||||
| GC12912 | BCATc Inhibitor 2 | 406191-34-2 | >99.00% | |
A selective BCATc inhibitor | ||||
| GC12981 | OU749 | 519170-13-9 | - | |
Inhibitor of γ-glutamyl transferase | ||||
| GC15442 | Tipifarnib (Zarnestra) | 192185-72-1 | >98.50% | |
A farnesyltransferase inhibitor with antitumor activity | ||||
| GC16129 | LY 78335 | 39959-66-5 | >95.00% | |
phenylethanolamine-N-methyltransferase (PNMT) inhibitor | ||||
| GC16310 | FTI 277 HCl | 180977-34-8 | >99.00% | |
FTI 277 HCl是一种强效且具有选择性的法尼基转移酶（FTase）抑制剂，IC 50 值为0.5nM，较香叶酰基香叶转移酶I（GGTase I）选择性高出约100倍。 | ||||
| GC16612 | GGsTop | 926281-37-0 | >95.00% | |
GGsTop是γ-谷氨酰转肽酶（GGT）的不可逆抑制剂（K i = 170μM）。 | ||||
| GC16738 | Tunicamycin Mixture | 11089-65-9 | >95.00% | |
Tunicamycin Mixture是一种同源核苷抗生素的混合物, 可抑制N-糖基化并阻断GlcNAc 磷酸转移酶（GPT）。 | ||||
| GC17046 | Tris DBA | 51364-51-3 | - | |
N-myristoyltransferase-1 (NMT-1) inhibitor | ||||
| GC17780 | FTase Inhibitor II | 156707-43-6 | >98.50% | |
Ftase inhibitor | ||||
| GP26139 | CHST3 Human | - | - | |
CHST3 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 450 amino acids (39-479 | ||||
| GP26140 | CHST5 Human | - | - | |
CHST5 Human produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 380 amino acids (27-395 a | ||||
| GP26156 | GST S. Japonicum, His | - | - | |
GST S | ||||
| GP26157 | GST S. Japonicum | - | - | |
GST S | ||||