Phospholipase
Phospholipase(磷脂酶)
Phospholipases are enzymes that catalyze the hydrolysis of phospholipids into fatty acids and other lipid mediators. It plays a variety of roles in tumorgenesis , inflammation and brain disorders etc.
Phospholipase 相关产品(130)
- GC17203Varespladib (LY315920)CAS: 172732-68-2纯度: >98.50% / >98.00%
Varespladib (LY315920)是一种强效、选择性的group IIA, nonpancreatic secretory PLA2 (sPLA2)抑制剂,IC 50 值为9nM。
- GC11021Bromoenol lactoneCAS: 88070-98-8纯度: >98.00%
A selective, potent, irreversible inhibitor of iPLA 2
- GC13930N-(p-amylcinnamoyl) Anthranilic AcidCAS: 110683-10-8
A TRP channel blocker and PLA 2 inhibitor
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC12880 | GSK 2830371 | 1404456-53-6 | >98.50% | |
An inhibitor of Wip1 phosphatase | ||||
| GC16418 | CP-91149 | 186392-40-5 | >99.50% | |
A glycogen phosphorylase inhibitor | ||||
| GC17203 | Varespladib (LY315920) | 172732-68-2 | >98.50% / >98.00% | |
Varespladib (LY315920)是一种强效、选择性的group IIA, nonpancreatic secretory PLA2 (sPLA2)抑制剂,IC 50 值为9nM。 | ||||
| GC19186 | GW4869 | 6823-69-4 | >98.00% | |
GW4869是一种非竞争性中性鞘脂酶抑制剂,IC50为1微摩尔。 | ||||
| GC10162 | JJKK 048 | 1515855-97-6 | >98.00% | |
JJKK 048 是一种超强效和高选择性的单酰基甘油脂肪酶 (MAGL) 抑制剂。 | ||||
| GC10451 | U-73122 | 112648-68-7 | >98.00% | |
U-73122是有效的、选择性的磷脂酶C(PLC)抑制剂,IC 50 值约为1-2.1μM,也可抑制5-脂氧合酶(5-LO)。 | ||||
| GC10565 | 7-hydroxycoumarinyl Arachidonate | 161180-11-6 | >98.00% | |
A substrate for cPLA 2 | ||||
| GC10645 | MJ33 (lithium salt) | 1007476-63-2 | ≥95.00% | |
An inhibitor of the PLA 2 activity of Prdx6 | ||||
| GC11021 | Bromoenol lactone | 88070-98-8 | >98.00% | |
A selective, potent, irreversible inhibitor of iPLA 2 | ||||
| GC11055 | 10-Pyrene-PC | 95864-17-8 | - | |
A substrate for some PLA 2 s | ||||
| GC11073 | ML 298 hydrochloride | - | - | |
A selective inhibitor of PLD 2 | ||||
| GC11116 | Thioetheramide-PC | 116457-99-9 | >95.00% | |
A competitive, reversible inhibitor of sPLA 2 | ||||
| GC11243 | Halopemide | 59831-65-1 | >99.50% | |
Inhibitor of phospholipase D 1 and D 2 | ||||
| GC11520 | ST638 | 107761-24-0 | - | |
Tyrosine kinase inhibitor | ||||
| GC11631 | Melittin | 20449-79-0 | >98.00% | |
蜂毒肽是一种 PLA2 活化剂,可刺激低分子量 PLA2 的活性,而不会增加高分子量 PLA2 的活性。 | ||||
| GC12361 | Darapladib | 356057-34-6 | >99.50% | |
A reversible inhibitor of Lp-PLA 2 | ||||
| GC12411 | RHC 80267 | 83654-05-1 | >99.50% | |
RHC 80267是一种有效的、选择性二酰基甘油脂酶(DAGL)抑制剂,RHC 80267还能够抑制胆碱酯酶活性(IC₅₀=4μM),可抑制环氧化酶(COX)活性和磷脂酰胆碱的水解。 | ||||
| GC12420 | MAFP | 188404-10-6 | >98.00% | |
An inhibitor of MAGL, FAAH, cPLA 2 , and iPLA 2 | ||||
| GC13276 | Oleyloxyethyl Phosphorylcholine | 84601-19-4 | - | |
A PLA 2 inhibitor | ||||
| GC13351 | VU0359595 | 1246303-14-9 | >95.00% | |
A selective PLD 1 inhibitor | ||||
| GC13585 | YM 26734 | 144337-18-8 | - | |
A group IIA sPLA 2 inhibitor | ||||
| GC13620 | FIPI | 939055-18-2 | >99.00% | |
Potent inhibitor of PLD 1 and PLD 2 | ||||
| GC13930 | N-(p-amylcinnamoyl) Anthranilic Acid | 110683-10-8 | - | |
A TRP channel blocker and PLA 2 inhibitor | ||||
| GC13948 | GPi 688 | 918902-32-6 | - | |
GPi 688 是一种有效且具有口服活性的糖原磷酸化酶 (GPa) 抑制剂,对人肝 GPa、大鼠肝 GPa 和人骨骼肌 GPa 的 IC50 分别为 19 nM、61 nM 和 12 nM。 | ||||
