Phospholipase

Phospholipase(磷脂酶)

Phospholipases are enzymes that catalyze the hydrolysis of phospholipids into fatty acids and other lipid mediators. It plays a variety of roles in tumorgenesis , inflammation and brain disorders etc.

Phospholipase 相关产品(130)

  • GC12880 structure
    GC12880GSK 2830371
    CAS: 1404456-53-6
    纯度: >98.50%

    An inhibitor of Wip1 phosphatase

  • GC16418 structure
    GC16418CP-91149
    CAS: 186392-40-5
    纯度: >99.50%

    A glycogen phosphorylase inhibitor

  • GC17203 structure
    GC17203Varespladib (LY315920)
    CAS: 172732-68-2
    纯度: >98.50% / >98.00%

    Varespladib (LY315920)是一种强效、选择性的group IIA, nonpancreatic secretory PLA2 (sPLA2)抑制剂,IC 50 值为9nM。

  • GC19186 structure
    GC19186GW4869
    CAS: 6823-69-4
    纯度: >98.00%

    GW4869是一种非竞争性中性鞘脂酶抑制剂,IC50为1微摩尔。

  • GC10162 structure
    GC10162JJKK 048
    CAS: 1515855-97-6
    纯度: >98.00%

    JJKK 048 是一种超强效和高选择性的单酰基甘油脂肪酶 (MAGL) 抑制剂。

  • GC10451 structure
    GC10451U-73122
    CAS: 112648-68-7
    纯度: >98.00%

    U-73122是有效的、选择性的磷脂酶C(PLC)抑制剂,IC 50 值约为1-2.1μM,也可抑制5-脂氧合酶(5-LO)。

  • GC10565 structure
    GC105657-hydroxycoumarinyl Arachidonate
    CAS: 161180-11-6
    纯度: >98.00%

    A substrate for cPLA 2

  • GC10645 structure
    GC10645MJ33 (lithium salt)
    CAS: 1007476-63-2
    纯度: ≥95.00%

    An inhibitor of the PLA 2 activity of Prdx6

  • GC11021 structure
    GC11021Bromoenol lactone
    CAS: 88070-98-8
    纯度: >98.00%

    A selective, potent, irreversible inhibitor of iPLA 2

  • GC11055 structure
    GC1105510-Pyrene-PC
    CAS: 95864-17-8

    A substrate for some PLA 2 s

  • GC11073 structure
    GC11073ML 298 hydrochloride

    A selective inhibitor of PLD 2

  • GC11116 structure
    GC11116Thioetheramide-PC
    CAS: 116457-99-9
    纯度: >95.00%

    A competitive, reversible inhibitor of sPLA 2

  • GC11243 structure
    GC11243Halopemide
    CAS: 59831-65-1
    纯度: >99.50%

    Inhibitor of phospholipase D 1 and D 2

  • GC11520 structure
    GC11520ST638
    CAS: 107761-24-0

    Tyrosine kinase inhibitor

  • GC11631 structure
    GC11631Melittin
    CAS: 20449-79-0
    纯度: >98.00%

    蜂毒肽是一种 PLA2 活化剂,可刺激低分子量 PLA2 的活性,而不会增加高分子量 PLA2 的活性。

  • GC12361 structure
    GC12361Darapladib
    CAS: 356057-34-6
    纯度: >99.50%

    A reversible inhibitor of Lp-PLA 2

  • GC12411 structure
    GC12411RHC 80267
    CAS: 83654-05-1
    纯度: >99.50%

    RHC 80267是一种有效的、选择性二酰基甘油脂酶(DAGL)抑制剂,RHC 80267还能够抑制胆碱酯酶活性(IC₅₀=4μM),可抑制环氧化酶(COX)活性和磷脂酰胆碱的水解。

  • GC12420 structure
    GC12420MAFP
    CAS: 188404-10-6
    纯度: >98.00%

    An inhibitor of MAGL, FAAH, cPLA 2 , and iPLA 2

  • GC13276 structure
    GC13276Oleyloxyethyl Phosphorylcholine
    CAS: 84601-19-4

    A PLA 2 inhibitor

  • GC13351 structure
    GC13351VU0359595
    CAS: 1246303-14-9
    纯度: >95.00%

    A selective PLD 1 inhibitor

  • GC13585 structure
    GC13585YM 26734
    CAS: 144337-18-8

    A group IIA sPLA 2 inhibitor

  • GC13620 structure
    GC13620FIPI
    CAS: 939055-18-2
    纯度: >99.00%

    Potent inhibitor of PLD 1 and PLD 2

  • GC13930 structure
    GC13930N-(p-amylcinnamoyl) Anthranilic Acid
    CAS: 110683-10-8

    A TRP channel blocker and PLA 2 inhibitor

  • GC13948 structure
    GC13948GPi 688
    CAS: 918902-32-6

    GPi 688 是一种有效且具有口服活性的糖原磷酸化酶 (GPa) 抑制剂,对人肝 GPa、大鼠肝 GPa 和人骨骼肌 GPa 的 IC50 分别为 19 nM、61 nM 和 12 nM。