GlpBio

Phospholipase

Phospholipase(磷脂酶)

Phospholipases are enzymes that catalyze the hydrolysis of phospholipids into fatty acids and other lipid mediators. It plays a variety of roles in tumorgenesis , inflammation and brain disorders etc.

Phospholipase 相关产品(130)

  • GC14090 structure
    GC14090o-3M3FBS
    CAS: 313981-55-4

    An inactive analog of m-3M3FBS

  • GC14521 structure
    GC14521ONO-RS-082
    CAS: 99754-06-0

    A PLA 2 inhibitor

  • GC15877 structure
    GC15877CP 316819
    CAS: 186392-43-8

    An inhibitor of glycogen phosphorylase A

  • GC15888 structure
    GC15888VU 0155069
    CAS: 1130067-06-9
    纯度: >98.00%

    Selective inhibitor of phospholipase D 1

  • GC16115 structure
    GC16115AACOCF3
    CAS: 149301-79-1
    纯度: >98.00%

    AACOCF3（花生四烯酰三氟甲基酮）是一种胞质磷脂酶A2（cPLA2）的强效抑制剂，IC50值约为10μM。AACOCF3通过不可逆烷基化酶活性位点阻断花生四烯酸释放及后续促炎性类二十烷酸生成，被广泛应用于炎症通路、神经炎症及脂质信号机制研究。

  • GC16286 structure
    GC16286m-3M3FBS
    CAS: 200933-14-8
    纯度: >97.00% / >98.00%

    An activator of phospholipase C

  • GC16364 structure
    GC16364LY 311727
    CAS: 164083-84-5
    纯度: >98.00%

    An inhibitor of Group IIA sPLA 2

  • GC16687 structure
    GC16687(R)-Edelfosine
    CAS: 77286-66-9
    纯度: >98.00% / >99.00%

    (R)-Edelfosine是一种属于具有抗肿瘤和抗寄生虫活性的合成脂质药物。(R)-Edelfosine可通过靶向线粒体和脂筏上的FOF1-ATP合酶，诱导肿瘤细胞发生凋亡样细胞死亡。

  • GC16714 structure
    GC16714PACOCF3
    CAS: 141022-99-3
    纯度: >98.00%

    Antagonizes DP receptor agonist effects

  • GC16770 structure
    GC16770Arachidonic Acid Leelamide

    A novel fatty acid amide

  • GC17420 structure
    GC17420OBAA
    CAS: 221632-26-4

    OBAA 是一种有效的磷脂酶 A2 (PLA2) 抑制剂，IC50 为 70 nM。

  • GC17684 structure
    GC17684VU 0364739 hydrochloride
    CAS: 1244640-48-9

    phospholipase D2 (PLD2) inhibitor

  • GC17851 structure
    GC17851D609
    CAS: 83373-60-8
    纯度: >98.00%

    A competitive inhibitor of PC-specific PLC

  • GC17889 structure
    GC17889ML 349
    CAS: 890819-86-0
    纯度: >99.00%

    ML 349是一种活性位点竞争性酰基蛋白硫酯酶2（APT2）抑制剂，K i 值为0.12μM。

  • GC17960 structure
    GC17960U 73343
    CAS: 142878-12-4
    纯度: >99.00%

    U 73343是U 73122的非活性类似物。

  • GC18039 structure
    GC18039ML 348
    CAS: 899713-86-1
    纯度: >99.50%

    ML 348是一种选择性的、可逆的溶血磷脂酶1（LYPLA1）抑制剂，IC 50 约为210nM，对LYPLA1的选择性是对LYPLA2的14倍。

  • GC18141 structure
    GC18141EA4
    CAS: 389614-94-2
    纯度: >98.50%

    An inhibitor of PLA 2 from red blood cells

  • GC18305 structure
    GC18305CAY10650
    CAS: 1233706-88-1
    纯度: >98.00%

    CAY10650是一种高效的细胞质磷脂酶A2α（cPLA2α）抑制剂，IC 50 值为12nM。

  • GC18559 structure
    GC18559Lysophosphatidylethanolamines (egg)
    CAS: 97281-40-8

    A mixture of lysophosphatidylethanolamines isolated from egg

  • GC18691 structure
    GC18691CAY10594
    CAS: 1130067-34-3

    CAY10594 是一种有效的磷脂酶 D2 (PLD2) 抑制剂（体外 IC50 为 140 nm，细胞内为 110 nm）。

  • GC19745 structure
    GC19745hnps-PLA Inhibitor
    CAS: 185298-58-2

    Hnps-PLA Inhibitor is an inhibitor of human nonpancreatic secretory Phospholipase A (hnps-PLA)

  • GC30180 structure
    GC30180ST271
    CAS: 106392-48-7
    纯度: >98.50%

    ST271 is a tyrphostin-like protein tyrosine kinase (PTK) inhibitor which inhibits phospholipase D (PLD) activity.

  • GC30464 structure
    GC30464Ecopladib (PLA 725)
    CAS: 381683-92-7

    Ecopladib (PLA 725) 是细胞溶质磷脂酶 A2α 的亚微摩尔抑制剂； (cPLA2α)，在 GLU 胶束和大鼠全血试验中，IC50 分别为 0.15 μM 和 0.11 μM。

  • GC30561 structure
    GC305612-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide
    CAS: 137089-36-2

    2-(E-2-decenoylamino)ethyl2-(cyclohexylethyl)sulfide是一种由压力诱发的溃疡和低毒性抑制剂，可以在压力引起的溃疡大鼠中，维持磷脂酶A2(phospholipaseA2)和前列腺素E2(prostaglandinE2)的含量水平。