Carbonic Anhydrase
Carbonic Anhydrase(碳酸酐酶)
Carbonic anhydrases (CAs) are a family of zinc containing metalloproteins that catalyze the reversible conversion of carbon dioxide (CO2) to bicarbonate with the releasing of a proton. Being encoded by three distinct and evolutionarily unrelated gene families, CA enzymes are divided into three subfamilies, α-CAs (in vertebrates, eubacteria, algae and cytoplasm of green plants), β-CAs (in eubacteria, algae and chloroplasts of both mono- and di-cotyledons) and γ-CAs (in Archaea and some eubacteria). Through extensive studies, fourteen different CA isozymes have been identified in mammals, including four cytosolic isozymes (CA I-III and CA VII), four membrane-bound isozymes (CA IV, CA IX, CA XII and CA XIV), one mitochondrial isozyme (CA V) and one secreted isozyme (CA VI).
Carbonic Anhydrase 相关产品(55)
- GC200955,7-Dihydroxy-4-methylcoumarinCAS: 2107-76-8
A synthetic coumarin with diverse biological activities
- GC31710Ethoxzolamide (Redupresin)CAS: 452-35-7纯度: >99.00%
Ethoxzolamide (Redupresin) 是一种碳酸酐酶抑制剂，Ki 为 1 nM。
- GC32634BenzthiazideCAS: 91-33-8纯度: >99.00% / >99.50%
Benzthiazide是一种长效的利尿剂和抗高血压剂。Benzthiazide为碳酸酐酶9(carbonicanhydrase9(CA9))的抑制剂，对CA9，CA2和CA1的Ki值分别为8.0，8.8和10nM。Benzthiazide能够抑制肿瘤细胞增殖。
- GC341862-Aminobenzenesulfonamide (Orthanilamide)CAS: 3306-62-5纯度: >99.50%
2-Aminobenzenesulfonamide (Orthanilamide, O-Aminobenzenesulfonamide, O-Sulfanilamide, Benzenesulfonamide) is an inhibitor of carbonic anhydrase IX.
- GC45802Zonisamide-13C2,15NCAS: 1188265-58-8纯度: >95.00%
An internal standard for the quantification of zonisamide
- GC46101Brinzolamide-d5CAS: 1217651-02-9纯度: >99.00%
An internal standard for the quantification of brinzolamide
- GC47210Dichlorphenamide-13C6CAS: 1391054-76-4纯度: >99.00%
An internal standard for the quantification of dichlorphenamide
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC10737 | Brinzolamide | 138890-62-7 | >99.00% | |
A potent carbonic anhydrase inhibitor | ||||
| GC14226 | Methazolamide | 554-57-4 | >98.00% | |
A carbonic anhydrase inhibitor | ||||
| GC16149 | Topiramate | 97240-79-4 | >98.00% | |
Topiramate是一种口服有效的磺胺衍生单糖，具有广谱抗癫痫活性。 | ||||
| GC17378 | U-104 | 178606-66-1 | >99.50% | |
A carbonic anhydrase inhibitor | ||||
| GC17748 | Dorzolamide HCl | 130693-82-2 | >99.50% | |
A carbonic anhydrase inhibitor | ||||
| GC11567 | Acetazolamide | 59-66-5 | >99.50% | |
An Analytical Reference Standard | ||||
| GC12992 | Fluorometholone Acetate | 3801-06-7 | >98.00% | |
A synthetic glucocorticoid | ||||
| GC13932 | Dorzolamide | 120279-96-1 | - | |
An Analytical Reference Standard | ||||
| GC14046 | Methyclothiazide | 135-07-9 | >99.50% | |
A thiazide diuretic | ||||
| GC15158 | Tioxolone | 4991-65-5 | >98.50% | |
A carbonic anhydrase I inhibitor | ||||
| GC17003 | Benzenesulfonamide | 98-10-2 | - | |
carbonic anhydrase inhibitor | ||||
| GC17454 | Dichlorphenamide | 120-97-8 | >98.00% | |
A carbonic anhydrase inhibitor | ||||
| GC18271 | Polmacoxib | 301692-76-2 | - | |
An inhibitor of COX-2 and carbonic anhydrase | ||||
| GC20095 | 5,7-Dihydroxy-4-methylcoumarin | 2107-76-8 | - | |
A synthetic coumarin with diverse biological activities | ||||
| GC30899 | Sultiame | 61-56-3 | >99.50% | |
A pan-CA inhibitor and an anticonvulsant | ||||
| GC31710 | Ethoxzolamide (Redupresin) | 452-35-7 | >99.00% | |
Ethoxzolamide (Redupresin) 是一种碳酸酐酶抑制剂，Ki 为 1 nM。 | ||||
| GC32634 | Benzthiazide | 91-33-8 | >99.00% / >99.50% | |
Benzthiazide是一种长效的利尿剂和抗高血压剂。Benzthiazide为碳酸酐酶9(carbonicanhydrase9(CA9))的抑制剂，对CA9，CA2和CA1的Ki值分别为8.0，8.8和10nM。Benzthiazide能够抑制肿瘤细胞增殖。 | ||||
| GC33491 | Acetazolamide D3 | 1189904-01-5 | - | |
AcetazolamideD3是Acetazolamide氘代化合物标准品。 | ||||
| GC34186 | 2-Aminobenzenesulfonamide (Orthanilamide) | 3306-62-5 | >99.50% | |
2-Aminobenzenesulfonamide (Orthanilamide, O-Aminobenzenesulfonamide, O-Sulfanilamide, Benzenesulfonamide) is an inhibitor of carbonic anhydrase IX. | ||||
| GC39792 | Halazone | 80-13-7 | - | |
Halazone (Pantocide, p-sulfondichloramidobenzoic acid) is widely used to disinfect drinking water. | ||||
| GC43874 | Hydroflumethiazide | 135-09-1 | >98.00% | |
A thiazide diuretic | ||||
| GC45802 | Zonisamide-13C2,15N | 1188265-58-8 | >95.00% | |
An internal standard for the quantification of zonisamide | ||||
| GC46101 | Brinzolamide-d5 | 1217651-02-9 | >99.00% | |
An internal standard for the quantification of brinzolamide | ||||
| GC47210 | Dichlorphenamide-13C6 | 1391054-76-4 | >99.00% | |
An internal standard for the quantification of dichlorphenamide | ||||