SGLT
SGLT(钠-葡萄糖协同转运蛋白)
SGLT (sodium-glucose linked transporter) uses the energy from the downhill sodium ion gradient created by the ATPase pump to transport glucose across the apical membrane against an uphill glucose gradient.
SGLT 相关产品(29)
- GC13771CanagliflozinCAS: 842133-18-0纯度: >99.50% / >98.00%
Canagliflozin是一种用于治疗2型糖尿病的钠葡萄糖共转运体（SGLT2）抑制剂。
- GC16212EmpagliflozinCAS: 864070-44-0纯度: >99.50% / >98.00%
Empagliflozin (BI 10773)是一种强效、竞争性、选择性的钠-葡萄糖共转运蛋白2（SGLT-2）抑制剂，对人源SGLT-2的IC 50 值为3.1nM。
- GC15530DapagliflozinCAS: 461432-26-8纯度: >99.50% / >98.00%
Dapagliflozin 是一种钠-葡萄糖协同转运蛋白 2 (SGLT2) 抑制剂，是一种新型抗糖尿病药物，由于其抑制 SGLT2 介导的肾葡萄糖重吸收的能力而被批准用于治疗 T2DM。
- GC19065BexagliflozinCAS: 1118567-05-7纯度: >99.00%
Bexagliflozin是一种具有高效选择性的钠-葡萄糖协同转运蛋白2（SGLT2）抑制剂，IC 50 值为2nM。
- GC31366Licogliflozin (LIK066)CAS: 1291094-73-9纯度: >98.00%
Licogliflozin (LIK066) 是一种钠葡萄糖协同转运蛋白（SGLT1 和 SGLT2）抑制剂。
- GC31377Tofogliflozin hydrate (CSG-452 hydrate)CAS: 1201913-82-7纯度: >98.50% / >98.00%
A potent inhibitor of SGLT2
- GC31461Tofogliflozin (CSG452)CAS: 903565-83-3
Tofogliflozin (CSG 452) is a novel sodium-glucose co-transporter 2(SGLT2) inhibitor with IC50 values of 2.9 nM and 8444 nM for hSGLT2 and hSGLT1, respectively.
- GC35809Dapagliflozin ((2S)-1,2-propanediol, hydrate)CAS: 960404-48-2纯度: >99.50%
Dapagliflozin propanediol belongs to the class of orally administered antidiabetic agents designated as sodiumglucose cotransporter 2 (SGLT2) inhibitors.
- GC36004Ertugliflozin L-pyroglutamic acidCAS: 1210344-83-4纯度: >99.50%
Ertugliflozin (MK-8835, PF-04971729) L-pyroglutamic acid is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2) with IC50 of 0.877 nM for h-SGLT2. Ertugliflozin has the potential for the treatment of type 2 diabetes mellitus.
- GC36326Ipragliflozin L-ProlineCAS: 951382-34-6
Ipragliflozin L-Proline is an orally active and selective inhibitor of SGLT2 with IC50 of 7.38 nM, 6.73 nM and 5.64 nM for human SGLT2, rat SGLT2 and mouse SGLT2, respectively.
- GC39178Canagliflozin D4CAS: 1997338-61-0
An internal standard for the quantification of canagliflozin
- GC41374TrilobatinCAS: 4192-90-9纯度: >99.00% / >98.00%
A dihydrochalcone glucoside with diverse biological activities
- GC60249MizagliflozinCAS: 666843-10-3纯度: >98.00% / >99.50%
Mizagliflozin是一种新型的SGLT1抑制剂，抑制常数Ki为27.0±1.5nM，可用于治疗糖尿病，改善餐后血糖波动。
- GC64266EnavogliflozinCAS: 1415472-28-4
Enavogliflozin (DWP-16001) 作为一种抗糖尿病药物，是一种具有口服活性，一流的选择性钠-葡萄糖协同转运体 -2 (SGLT-2) 抑制剂。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC13771 | Canagliflozin | 842133-18-0 | >99.50% / >98.00% | |
Canagliflozin是一种用于治疗2型糖尿病的钠葡萄糖共转运体（SGLT2）抑制剂。 | ||||
| GC16012 | PF-04971729 | 1210344-57-2 | >98.00% | |
An SGLT2 inhibitor | ||||
| GC16212 | Empagliflozin | 864070-44-0 | >99.50% / >98.00% | |
Empagliflozin (BI 10773)是一种强效、竞争性、选择性的钠-葡萄糖共转运蛋白2（SGLT-2）抑制剂，对人源SGLT-2的IC 50 值为3.1nM。 | ||||
| GC15088 | LX-4211 | 1018899-04-1 | >98.50% | |
LX-4211是一种口服的强效双重SGLT2/1抑制剂，对SGLT1和SGLT2的IC 50 值分别为36nM和1.8nM。 | ||||
| GC15530 | Dapagliflozin | 461432-26-8 | >99.50% / >98.00% | |
Dapagliflozin 是一种钠-葡萄糖协同转运蛋白 2 (SGLT2) 抑制剂，是一种新型抗糖尿病药物，由于其抑制 SGLT2 介导的肾葡萄糖重吸收的能力而被批准用于治疗 T2DM。 | ||||
| GC16469 | Ipragliflozin | 761423-87-4 | >99.50% | |
An SGLT2 inhibitor | ||||
| GC16697 | fluoro-Dapagliflozin | 1181681-43-5 | - | |
A potent inhibitor of hSGLT2 | ||||
| GC17190 | galacto-Dapagliflozin | 1408245-02-2 | - | |
A potent inhibitor of hSGLT2 | ||||
| GC17976 | Phloretin | 60-82-2 | >99.50% / >98.50% | |
A natural inhibitor of various transporters | ||||
| GC19065 | Bexagliflozin | 1118567-05-7 | >99.00% | |
Bexagliflozin是一种具有高效选择性的钠-葡萄糖协同转运蛋白2（SGLT2）抑制剂，IC 50 值为2nM。 | ||||
| GC31366 | Licogliflozin (LIK066) | 1291094-73-9 | >98.00% | |
Licogliflozin (LIK066) 是一种钠葡萄糖协同转运蛋白（SGLT1 和 SGLT2）抑制剂。 | ||||
| GC31377 | Tofogliflozin hydrate (CSG-452 hydrate) | 1201913-82-7 | >98.50% / >98.00% | |
A potent inhibitor of SGLT2 | ||||
| GC31461 | Tofogliflozin (CSG452) | 903565-83-3 | - | |
Tofogliflozin (CSG 452) is a novel sodium-glucose co-transporter 2(SGLT2) inhibitor with IC50 values of 2.9 nM and 8444 nM for hSGLT2 and hSGLT1, respectively. | ||||
| GC31593 | Velagliflozin | 946525-65-1 | - | |
Velagliflozin是一种可口服的钠-葡萄糖协同转运蛋白2(SGLT2)抑制剂，具有抗糖尿病的活性。 | ||||
| GC35603 | Canagliflozin hemihydrate | 928672-86-0 | >99.50% | |
An inhibitor of SGLT2 | ||||
| GC35809 | Dapagliflozin ((2S)-1,2-propanediol, hydrate) | 960404-48-2 | >99.50% | |
Dapagliflozin propanediol belongs to the class of orally administered antidiabetic agents designated as sodiumglucose cotransporter 2 (SGLT2) inhibitors. | ||||
| GC36004 | Ertugliflozin L-pyroglutamic acid | 1210344-83-4 | >99.50% | |
Ertugliflozin (MK-8835, PF-04971729) L-pyroglutamic acid is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2) with IC50 of 0.877 nM for h-SGLT2. Ertugliflozin has the potential for the treatment of type 2 diabetes mellitus. | ||||
| GC36326 | Ipragliflozin L-Proline | 951382-34-6 | - | |
Ipragliflozin L-Proline is an orally active and selective inhibitor of SGLT2 with IC50 of 7.38 nM, 6.73 nM and 5.64 nM for human SGLT2, rat SGLT2 and mouse SGLT2, respectively. | ||||
| GC36498 | LX2761 | 1610954-97-6 | - | |
LX2761 在体外是一种化学稳定性和有效性的钠依赖性葡萄糖协同转运蛋白1 (SGLT1) 和 SGLT2 抑制剂，对hSGLT1 和 hSGLT2 的 IC50 值分别为 2.2 nM 和 2.7 nM，但在胃肠道 (GI) 表现出特定的 SGLT1 抑制作用。 | ||||
| GC39178 | Canagliflozin D4 | 1997338-61-0 | - | |
An internal standard for the quantification of canagliflozin | ||||
| GC41374 | Trilobatin | 4192-90-9 | >99.00% / >98.00% | |
A dihydrochalcone glucoside with diverse biological activities | ||||
| GC60249 | Mizagliflozin | 666843-10-3 | >98.00% / >99.50% | |
Mizagliflozin是一种新型的SGLT1抑制剂，抑制常数Ki为27.0±1.5nM，可用于治疗糖尿病，改善餐后血糖波动。 | ||||
| GC64266 | Enavogliflozin | 1415472-28-4 | - | |
Enavogliflozin (DWP-16001) 作为一种抗糖尿病药物，是一种具有口服活性，一流的选择性钠-葡萄糖协同转运体 -2 (SGLT-2) 抑制剂。 | ||||
| GC69241 | HSK0935 | 1638851-44-1 | >96.00% | |
HSK0935是高效，高选择性，口服可用的 SGLT2 抑制剂。IC50为1.3 nM。具有抗高血糖功效。 | ||||