GlpBio

Ertugliflozin L-pyroglutamic acid

目录号: GC36004纯度: >99.50%同义词: 埃格列净,PF-04971729 L-pyroglutamic acid
Ertugliflozin (MK-8835, PF-04971729) L-pyroglutamic acid is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2) with IC50 of 0.877 nM for h-SGLT2. Ertugliflozin has the potential for the treatment of type 2 diabetes mellitus.
Ertugliflozin L-pyroglutamic acid
Cas No.: 1210344-83-4
规格价格库存数量操作
5mg¥243.00现货
1
10mg¥316.00现货
1
25mg¥457.00现货
1
50mg¥686.00现货
1
100mg¥1,033.00现货
1
200mg¥1,558.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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    Cell
    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

Ertugliflozin (MK-8835, PF-04971729) L-pyroglutamic acid is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2) with IC50 of 0.877 nM for h-SGLT2. Ertugliflozin has the potential for the treatment of type 2 diabetes mellitus.

[1] Meiyan Jiang, Peter S Steyger. Expert Opin Ther Pat. 2015;25(11):1349-52.

产品文档 Product Documents

Purity:>99.50%

化学性质Chemical Properties

CAS 号
1210344-83-4
同义词
埃格列净,PF-04971729 L-pyroglutamic acid
SMILES
ClC1=CC=C([C@]23O[C@@](CO)(CO3)[C@@H](O)[C@H](O)[C@H]2O)C=C1CC4=CC=C(OCC)C=C4.O=C5CC[C@@H](C(O)=O)N5
分子式
C27H32ClNO10
分子量
566 g/mol
溶解性
DMSO: ≥ 125 mg/mL (220.85 mM)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol