5-Lipoxygenase

5-Lipoxygenase(5-脂氧合酶)

5-lipoxygenase catalyzes oxidation of AA at the 5-position to yield 5-HpETE and is a current target for pharmaceutical intervention in a number of diseases such as asthma, atherosclerosis and several cancers.

5-Lipoxygenase 相关产品(11)

  • GC10451 structure
    GC10451U-73122
    CAS: 112648-68-7
    纯度: >98.00%

    U-73122是有效的、选择性的磷脂酶C(PLC)抑制剂,IC 50 值约为1-2.1μM,也可抑制5-脂氧合酶(5-LO)。

  • GC14435 structure
    GC14435Zileuton sodium
    CAS: 118569-21-4

    A reversible inhibitor of 5-lipoxygenase

  • GC14751 structure
    GC14751Malotilate
    CAS: 59937-28-9
    纯度: >99.50%

    A hepatoprotective agent

  • GC16014 structure
    GC16014Zileuton
    CAS: 111406-87-2
    纯度: >99.00%

    Zileuton是一种苯并噻吩N-羟基脲类化合物,作为口服5-脂氧合酶抑制剂。

  • GC10331 structure
    GC10331Ebselen
    CAS: 60940-34-3
    纯度: 99.97%

    Ebselen一种具有谷胱甘肽过氧化物酶样活性的硒代有机化合物,是一种抗炎和抗氧化剂。Ebselen是肌醇单磷酸酶(IMPase)的抑制剂,IC 50 为1.5μM。

  • GC10821 structure
    GC1082111-keto-β-Boswellic Acid
    CAS: 17019-92-0
    纯度: >99.50%

    A 5-LO inhibitor

  • GC12159 structure
    GC12159HZ52
    CAS: 1077626-51-7

    A reversible inhibitor of 5-lipoxygenase

  • GC13379 structure
    GC133791-Naphthyl 3,5-dinitrobenzoate
    CAS: 93261-39-3

    A dual inhibitor of 5-LO and mPGES-1

  • GC14282 structure
    GC14282AKBA (3-acetyl-11-keto-β-Boswellic Acid)
    CAS: 67416-61-9
    纯度: >98.00%

    AKBA (3-acetyl-11-keto-β-Boswellic Acid)是一种五环三萜酸,能够有效地非竞争性地抑制5-脂氧合酶(5-lipoxygenase, 5-LOX),具有抗炎、抗肿瘤、神经保护等多种生物活性。

  • GC14601 structure
    GC14601BW 755C
    CAS: 66000-40-6

    Dual 5-LO/COX inhibitor

  • GC16046 structure
    GC16046Piriprost (potassium salt)
    CAS: 88851-62-1

    A novel 5-lipoxygenase inhibitor