GlpBio

Dopamine β-hydroxylase

Dopamine β-hydroxylase(多巴胺β-羟化酶)

DBH (Dopamine-β-hydroxylase) is a copper-containing monooxygenase that catalyzes the biosynthesis of catecholamine neurotransmitter, norepinephrine from dopamine. Deficiency in DBH causes orthostatic hypotension, autonomic disorders etc.

Dopamine β-hydroxylase 相关产品(10)

  • GC10801 structure
    GC10801Disulfiram
    CAS: 97-77-8
    纯度: >99.50%

    An irreversible inhibitor of aldehyde dehydrogenase

  • GC12596 structure
    GC12596Nepicastat (SYN-117) HCl
    CAS: 170151-24-3
    纯度: >98.50%

    An inhibitor of dopamine β-hydroxylase

  • GC15382 structure
    GC15382Isotretinoin
    CAS: 4759-48-2
    纯度: >99.50%

    A retinoid

  • GC15558 structure
    GC15558Mildronate
    CAS: 76144-81-5
    纯度: >98.00%

    An inhibitor of carnitine biosynthesis

  • GC18061 structure
    GC18061Fusaric Acid
    CAS: 536-69-6
    纯度: >98.00% / >97.00%

    镰刀菌酸是一种由镰刀菌产生的真菌毒素，对动植物具有多种毒理作用。

  • GC32575 structure
    GC32575Etamicastat (BIA 5-453)
    CAS: 760173-05-5

    Etamicastat (BIA 5-453) (BIA 5-453) 是一种有效且可逆的多巴胺-β-羟化酶 (DBH) 抑制剂，IC50 值为 107 nM。

  • GC32593 structure
    GC32593Zamicastat (BIA 5-1058)
    CAS: 1080028-80-3
    纯度: >98.00%

    Zamicastat (BIA 5-1058) (BIA 5-1058) 是一种多巴胺 β-羟化酶 (DBH) 抑制剂，可穿过血脑屏障 (BBB) 引起中枢和外周效应。

  • GC36722 structure
    GC36722Nepicastat
    CAS: 173997-05-2

    An inhibitor of dopamine β-hydroxylase

  • GC60519 structure
    GC605194-Hydroxyderricin
    CAS: 55912-03-3
    纯度: >98.00%

    4-Hydroxyderricin(4-HD), the major active ingredients of Angelica keiskei Koidzumi, is a potent selective monoamine oxidase (MAO) inhibitor with mild inhibitory effect on dopamine β-hydroxylase.

  • GC10718 structure
    GC10718PF 915275
    CAS: 857290-04-1
    纯度: >99.50%

    PF 915275 是一种有效的、选择性的、具有口服活性的人 11β-羟基类固醇脱氢酶 1 型 (11βHSD1) 抑制剂，Ki 为 2.3 nM，EC50 为 15 nM（在 HEK293 细胞中）。