NSC 44625 is an inhibitor of carbonic anhydrase II (CAII; Ki = 63 nM for the human enzyme).[1] It is selective for CAII over CAI (Ki = 5,800 nM for the human enzyme) but also inhibits β-carbonic anhydrase (Ki = 223 nM for the S. cerevisiae enzyme).
References:
[1].Isik, S., Kockar, F., Aydin, M., et al.Carbonic anhydrase inhibitors: inhibition of the β-class enzyme from the yeast Saccharomyces cerevisiae with sulfonamides and sulfamatesBioorg. Med. Chem.17(3)1158-1163(2009).