GPCR/G protein(G 蛋白偶联受体/G 蛋白)
- Neuropeptide FF/AF Receptors(49)
- Formyl Peptide Receptors(10)
- 5-HT Receptor(481)
- Acetylcholine(28)
- Adenosine Deaminase(9)
- Adenosine Receptor(130)
- Adenosine Kinase(4)
- Adiponectin Receptor(3)
- Adrenergic Receptor(404)
- Adrenergic Transporters(5)
- Apelin Receptor(9)
- Angiotensin Receptor(111)
- Bombesin Receptors(23)
- Bradykinin Receptors(29)
- Calcitonin and Related Receptors(10)
- Cannabinoid Receptor(116)
- Calcimimetic Agent(2)
- CaSR(20)
- CCK1 Receptors(7)
- CCK2 Receptors(7)
- CCR(78)
- Chemokine Receptors(23)
- CRF1 Receptors(9)
- CRF2 Receptors(3)
- CXCR(78)
- CysLT1 receptor(1)
- Endothelin Receptor(50)
- EP1 Receptor(2)
- EP4 Receptor(2)
- ERRγ(1)
- ETA Receptors(5)
- ETB Receptors(5)
- Free Fatty Acid Receptors(16)
- Galanin Receptors(11)
- Ghrelin Receptors(11)
- GHSR(19)
- GIP Receptor(5)
- Glucagon Receptor(58)
- Glucocorticoid Receptor(95)
- GLUT1(1)
- Gonadotropin-Releasing Hormone Receptors(3)
- GPCR19(12)
- GPR109A(4)
- GPR119(10)
- GPR120(9)
- GPR35(10)
- GPR55(10)
- Hydroxycarboxylic Acid Receptors(5)
- Leukotriene Receptor(55)
- LPA Receptor(12)
- LPL Receptor(59)
- LTD4 Receptor(1)
- mGluR (119)
- Melanin-concentrating Hormone Receptors(7)
- Melanocortin (MC) Receptors(54)
- Melatonin Receptors(23)
- Motilin Receptor(7)
- MT Receptor(1)
- Non-selective CRF(7)
- Neurotensin Receptors(23)
- NK2 Receptors(7)
- NK3 Receptor(5)
- NOP Receptor(19)
- NPY Receptors(26)
- Orexin(3)
- Orphan 7-TM Receptors(6)
- OX Receptor(47)
- Oxytocin Receptors(22)
- P2Y Receptor(60)
- PACAP Receptors(3)
- PAF Receptors(7)
- Peptide Receptors(14)
- PGD2 Receptor(1)
- Prostaglandin Receptor(170)
- Protease-Activated Receptors(9)
- RGS(2)
- S1P receptor(8)
- Secretin Receptors(1)
- Sensory Neuron-Specific Receptors(1)
- Somatostatin Receptor(39)
- Sigma Receptor(58)
- Vasopressin Receptor(33)
- 17,20-lyase(4)
- Ras(138)
- Urotensin-II Receptor(10)
- VIP Receptors(6)
- EBI2/GPR183(5)
- TSH Receptor(10)
- NK Receptor(1)
- GPR81(1)
- C3aR(1)
- CysLT2 receptor(1)
- S1P receptor inhibitor(22)
- CCKB(1)
- FFAR1 (GPR40)(20)
- GPR84(8)
- Neuromedin U Receptors(2)
- Kisspeptin Receptor(5)
- CRFR(25)
- RGS Protein(5)
- Urotensin Receptor(6)
- Cholecystokinin Receptor(25)
- GPR139(4)
- mAChR(183)
- MCHR1 (GPR24)(16)
- Neurokinin Receptor(75)
- Neuropeptide S Receptor(1)
- GPBA Receptor(1)
- Trace Amine 1 Receptor(2)
- GPCR protein(1)
- FFAR3(1)
- cGMP(26)
- GRK(1)
- GCGR(2)
- GLP Receptor(2)
- PTHR(1)
- Protease Activated Receptor (PAR)(2)
- Free Fatty Acid Receptor(1)
- Formyl Peptide Receptor (FPR)(1)
- Cat.No. 产品名称 Information
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GC19239
Mapracorat
ZK-245186; BOL-303242X
Mapracorat 是一种新型非甾体选择性糖皮质激素受体激动剂。
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GC19231
LY2828360
A selective CB2 receptor agonist
-
GC19230
LY2510924
LY2510924 是一种有效的选择性 CXCR4 拮抗剂；阻断 SDF-1 与 CXCR4 的结合，IC50 为 0.079 nM。
-
GC19220
Lemborexant
莱博雷生,E-2006
Lemborexant (E2006) 是一种口服活性双食欲素受体拮抗剂 (DORA)，已获得美国食品和药物管理局批准用于治疗失眠。
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GC19209
JNJ-63533054
3-氯-N-[2-氧代-2-[[(1S)-1-苯基乙基]氨基]乙基]苯甲酰胺
JNJ-63533054 是一种有效的选择性 hGPR139 激动剂，EC50 = 16nM。
-
GC19207
JNJ-42153605
A positive allosteric modulator of mGlurR2
-
GC19197
IB-MECA
IB-MECA; CF-101
An adenosine A3 receptor agonist
-
GC19176
GSK163090
GSK163090 是一种有效的、选择性的和具有口服活性的 5-HT1A/1B/1D 受体拮抗剂，pKi 值分别为 9.4/8.5/9.7。
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GC19170
Glucagon receptor antagonists-4
Glucagon receptor antagonists-4
A GCGR antagonist
-
GC19164
GGTI298 Trifluoroacetate
GGTI298 Trifluoroacetate是一种选择性、不可逆的香叶基香叶酰转移酶I（GGTase-I）抑制剂（IC50 = 3μM)。
-
GC19153
Fevipiprant
非韦匹仑,QAW039; NVP-QAW039
A DP2/CRTH2 antagonist
-
GC19147
Evatanepag
2-[3-[N-(4-叔丁基苄基)-N-(吡啶-3-基磺酰基)氨基甲基]苯氧基]乙酸,CP-533536 free acid
Evatanepag (CP-533536) 是一种非前列腺素、强效和选择性 EP2 受体激动剂。
-
GC19146
Etrasimod
APD334
A potent S1P1 receptor antagonist
-
GC19137
EMA401
EMA401; PD-126055
A selective AT2 receptor antagonist
-
GC19116
Danirixin
GSK1325756
A CXCR2 antagonist
-
GC19101
Cenicriviroc
TAK-652; TBR-652
Cenicriviroc (CVC) 是一种口服的 CCR2/CCR5 双重拮抗剂，对这两种受体具有纳摩尔效力。
-
GC19100
Cenerimod
ACT-334441
A S1P1 receptor modulator
-
GC19087
Capromorelin Tartrate
卡普瑞林酒石酸盐,CP 424391-18
A growth hormone secretagogue and GHS-R1a agonist
-
GC19081
BPTU
BMS-646786
A P2Y1 receptor antagonist
-
GC19078
BMS-986020
AM152
An LPA1 receptor antagonist
-
GC19077
BMS-813160
A dual antagonist of CCR2 and CCR5
-
GC19071
BIBS 39
A nonpeptide AT1 receptor antagonist
-
GC19060
Bay 59-3074
A partial agonist of CB1 and CB2 receptors
-
GC19051
AZD7594
AZD7594; AZ13189620
AZD7594 是一种有效的选择性非甾体糖皮质激素受体调节剂，IC50 为 0.9 nM。
-
GC19049
AZD4635
HTL1071; AZD4635
AZD4635是一种强效、选择性的口服腺苷2A受体（A2AR）抑制剂，Ki值为1.7nM。
-
GC19037
ARS-853
An inhibitor of KRASG12C
-
GC19033
APD597
JNJ-38431055
An agonist of GPR119
-
GC19032
AVex-73 hydrochloride
Anavex 2-73
AVex-73 hydrochloride 是一种 Sigma-1 Receptor 激动剂，IC50 为 860 nM。
-
GC19031
Amiselimod hydrochloride
MT-1303盐酸盐,MT-1303 hydrochloride
A prodrug form of amiselimod phosphate
-
GC19030
AMG 837
(BETAS)-BETA-1-丙炔-1-基-4-[[4'-(三氟甲基)[1,1'-联苯]-3-基]甲氧基]苯丙酸
An FFAR1 (GPR40) partial
-
GC19023
AF38469
AF38469是一种具有口服活性的Sortilin（SORT1；IC50=330nM）受体抑制剂。
-
GC18951
Obscurolide A1
A phosphodiesterase inhibitor
-
GC18867
SER-601
A selective CB2 receptor agonist
-
GC18866
MCHB-1
NMethylcyclohexyl benzimidazole analog 1
A CB2 receptor agonist
-
GC18719
Docosatetraenoyl Ethanolamide
DEA
An endocannabinoid
-
GC18678
CAY10595
A potent CRTH2/DP2 receptor antagonist
-
GC18661
Vercirnon
维塞诺; GSK-1605786; CCX282-B; Traficet-EN
Vercirnon是一种新型的、具有口服活性的CCR9趋化因子受体选择性拮抗剂，抑制CCR9介导的Molt-4细胞钙离子动员和趋化作用的IC₅₀值分别为5.4nM和3.4nM
-
GC18648
Echothiophate (iodide)
碘依可酯,Echothiophate iodide
An AChE inhibitor
-
GC18501
Kendomycin
(-)-TAN2162
A cytotoxic macrolide
-
GC18496
Leelamine (hydrochloride)
脱氢松香胺盐酸盐
An inhibitor of pyruvate dehydrogenase kinase
-
GC18472
Elinogrel
5-氯-N-[[[4-[6-氟-1,4-二氢-7-(甲基氨基)-2,4-二氧代-3(2H)-喹唑啉基]苯基]氨基]羰基]-2-噻吩磺酰胺,PRT060128
A reversible P2Y12 antagonist
-
GC18458
Terrein
土曲霉酮
A fungal metabolite with diverse biological activities
-
GC18435
Arachidonoyl 2'-Chloroethylamide
ACEA, 2'-chloro-AEA
A potent and selective CB1 receptor agonist
-
GC18412
VU0409551 (JNJ-46778212)
VU 0409551
VU0409551 (JNJ-46778212)是一种强效且选择性的偏向性代谢型谷氨酸受体5亚型正变构调节剂（mGlu5 PAM；EC50=260nM）。
-
GC18348
Ceralifimod
ONO-4641
An agonist of S1P1 and S1P5 receptors
-
GC18327
Todralazine (hydrochloride)
盐酸托屈嗪,Ecarazine hydrochloride
A β2-adrenergic receptor antagonist
-
GC18318
CAY10441
RO1138452
An IP receptor antagonist
-
GC18255
Xanomeline (oxalate)
诺美林草酸盐,LY246708 oxalate
Potent agonist of muscarinic receptors
-
GC18244
Eltoprazine (hydrochloride)
1-(2,3-二氢苯并[B][1,4]二氧杂芑-5-基)哌嗪,DU 28853 hydrochloride
A partial agonist of 5-HT1A, 5-HT1B, and 5-HT2B receptors
-
GC18216
ML314
An NTS1 agonist
