GlpBio

Leukotriene Receptor

Leukotriene Receptor(白三烯受体)

Leukotrienes receptors are divided into two types, BLT receptors and CycLT receptors. BLT receptors mediate chemoattraction. CysLT receptors mediate pro-inflammatory effects including constriction of airways ad smooth muscle contraction.

Leukotriene Receptor 相关产品(55)

  • GC15839 structure
    GC15839Zafirlukast
    CAS: 107753-78-6
    纯度: >99.50%

    A selective CysLT 1 receptor antagonist

  • GC10020 structure
    GC10020γ-Linolenic Acid methyl ester
    CAS: 16326-32-2

    A dietary ω-6 PUFA

  • GC10189 structure
    GC10189LY223982
    CAS: 117423-74-2
    纯度: >99.00%

    A LTB 4 receptor antagonist

  • GC10266 structure
    GC10266BAY-u 9773
    CAS: 154978-38-8

    Antagonist of CysLT1/CysLT2 receptors

  • GC10283 structure
    GC10283γ-Linolenic Acid
    CAS: 506-26-3
    纯度: >98.00% / >98.50%

    γ-Linolenic Acid是一种来源于琉璃苣油的口服ω-6多不饱和脂肪酸，可作为β-分泌酶（BACE1）的特异性抑制剂，IC 50 值为7.6×10 −5 mol/L，K i 值为3.5×10 −5 mol/L。

  • GC10821 structure
    GC1082111-keto-β-Boswellic Acid
    CAS: 17019-92-0
    纯度: >99.50%

    A 5-LO inhibitor

  • GC10992 structure
    GC10992LY 255283
    CAS: 117690-79-6
    纯度: >98.50%

    A BLT 2 receptor antagonist

  • GC11006 structure
    GC11006Montelukast Sodium
    CAS: 151767-02-1

    A CysLT 1 receptor antagonist

  • GC11201 structure
    GC11201ARM1
    CAS: 68729-05-5

    An inhibitor of LTA 4 hydrolase

  • GC11283 structure
    GC11283FPL 55712
    CAS: 40785-97-5

    A leukotriene receptor antagonist

  • GC12197 structure
    GC12197MK 571
    CAS: 115104-28-4
    纯度: >98.00%

    A selective CysLT 1 receptor antagonist

  • GC12230 structure
    GC12230Cinalukast
    CAS: 128312-51-6

    CysLT1 (LTD4) leukotriene receptor antagonist

  • GC12232 structure
    GC12232BAY-X 1005
    CAS: 128253-31-6
    纯度: >98.50%

    BAY-X 1005 (BAY X 1005; DG-031) 是一种具有口服活性的选择性 5-脂氧合酶活化蛋白 (FLAP) 抑制剂。

  • GC13087 structure
    GC13087LY171883
    CAS: 88107-10-2

    Selective, potent LTD 4 receptor antagonist

  • GC13497 structure
    GC13497BML-111
    CAS: 78606-80-1
    纯度: >95.00%

    A potent bioactive analog of lipoxin A 4

  • GC14094 structure
    GC14094Pranlukast
    CAS: 103177-37-3
    纯度: >99.50%

    A CysLT 1 receptor antagonist

  • GC14939 structure
    GC14939REV 5901
    CAS: 101910-24-1

    An antagonist of cysteinyl-leukotriene receptors

  • GC14980 structure
    GC14980MK-571 sodium salt hydrate
    CAS: 115103-85-0
    纯度: >98.00%

    MK-571 钠盐水合物，作为白三烯 D4 作用的强效特异性拮抗剂，用于治疗哮喘。

  • GC15298 structure
    GC15298SR 2640 hydrochloride
    CAS: 146662-42-2

    SR2640（盐酸盐）是一种有效的选择性竞争性白三烯 D4/白三烯 E4 拮抗剂。

  • GC17000 structure
    GC17000Nedocromil
    CAS: 69049-73-6
    纯度: >98.50%

    A mast cell stabilizer

  • GC17092 structure
    GC17092HAMI3379
    CAS: 1245653-57-9
    纯度: >90.00% / >99.50% / >98.00%

    HAMI3379是首个被报道的强效选择性半胱氨酰白氧合肽（CysLT₂）受体拮抗剂，也被鉴定为孤儿G蛋白偶联受体GPR17的拮抗剂。

  • GC30453 structure
    GC30453LM-1484
    CAS: 197506-02-8

    LM-1484是CysLT1受体的拮抗剂，对3H-LTC4位点具有很高的亲和性。

  • GC30604 structure
    GC30604Darbufelone mesylate (CI-1004 mesylate)
    CAS: 139340-56-0
    纯度: >98.00%

    Darbufelone mesylate (CI-1004 mesylate) (CI-1004 mesylate) 是细胞 PGF2α 的双重抑制剂；和 LTB4 生产。

  • GC31774 structure
    GC31774AS-35
    CAS: 108427-72-1

    AS-35是一种有效的，可口服的，选择性的leukotrienes拮抗剂，抑制LTC4，LTD4和LTE4诱导的回肠收缩,IC50值分别为8nM，4nM和3nM，具有抗过敏的功效。