mGluR
mGluR (代谢型谷氨酸受体)
The mGluR (metabotropic glutamate receptor) is a group C GPCR and is active through an indirect metabotropic process.
mGluR 相关产品(119)
- GC16523DipraglurantCAS: 872363-17-2纯度: >99.50%
Dipraglurant (ADX48621) 是一种有效的、选择性的、具有口服活性和脑渗透性的 mGluR5 负变构调节剂 (NAM)，IC50 为 21 nM。
- GC11459Xanthurenic acidCAS: 59-00-7纯度: >99.50% / >98.00%
Xanthurenic acid是一种内源性II组代谢型谷氨酸受体激动剂，参与丘脑的感觉传递。
- GC12485Ro 67-7476CAS: 298690-60-5纯度: >98.00% / >99.00% / >99.50%
A positive allosteric modulator of mGluR1
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC10864 | MPEP | 96206-92-7 | - | |
MPEP是一种非竞争性、选择性的、强效、有口服活性和系统活性的mGlu5受体拮抗剂，其完全抑制quisqualate 刺激的磷酸肌醇水解的IC 50 为36nM。 | ||||
| GC13426 | CPPHA | 693288-97-0 | - | |
A positive allosteric modulator of the mGluR5 | ||||
| GC16523 | Dipraglurant | 872363-17-2 | >99.50% | |
Dipraglurant (ADX48621) 是一种有效的、选择性的、具有口服活性和脑渗透性的 mGluR5 负变构调节剂 (NAM)，IC50 为 21 nM。 | ||||
| GC16619 | CTEP (RO4956371) | 871362-31-1 | >98.00% | |
A mGluR5 inverse agonist | ||||
| GC17498 | L-Glutamine | 56-85-9 | >99.00% / >98.00% | |
A conditionally essential amino acid | ||||
| GC18087 | VU 0357121 | 433967-28-3 | >99.50% | |
A positive allosteric modulator of mGluR5 | ||||
| GC10123 | O-Phospho-L-serine | 407-41-0 | >98.00% | |
A glutamate receptor agonist | ||||
| GC10494 | ADX-47273 | 851881-60-2 | >99.00% | |
A positive allosteric modulator of mGluR5 | ||||
| GC10605 | LY 354740 | 176199-48-7 | >98.00% | |
An agonist of mGluR2 and mGluR3 | ||||
| GC11182 | LY404039 | 635318-11-5 | >98.00% | |
An agonist of mGluR2 and mGluR3 | ||||
| GC11459 | Xanthurenic acid | 59-00-7 | >99.50% / >98.00% | |
Xanthurenic acid是一种内源性II组代谢型谷氨酸受体激动剂，参与丘脑的感觉传递。 | ||||
| GC11501 | TCN 238 | 125404-04-8 | >98.00% | |
A positive allosteric modulator of mGluR4 | ||||
| GC11667 | VU0483605 | 1623101-11-0 | - | |
A selective mGlu1 PAM | ||||
| GC11766 | Fenobam | 57653-26-6 | >99.50% | |
A noncompetitive antagonist and inverse agonist of mGluR5 | ||||
| GC11871 | MTEP hydrochloride | 1186195-60-7 | >98.00% | |
A selective mGlu5a receptor antagonist | ||||
| GC11954 | mGlu2 agonist | 1311385-32-6 | >98.00% | |
mGlu2 激动剂是 2812223 的丙氨酸前药，是一种选择性和有效的正构 mGlu2 受体激动剂。 | ||||
| GC11966 | O-Phospho-D-Serine | 73913-63-0 | - | |
weak agonist of the metabotropic glutamate receptor mGluR4 | ||||
| GC12238 | Oxomemazine | 3689-50-7 | - | |
Oxomemazine 是一种基于吩噻嗪的组胺 H1 受体阻滞剂，具有明显的抗毒蕈碱特性。 | ||||
| GC12279 | (RS)-MCPG | 146669-29-6 | >99.50% | |
(RS)-MCPG (alpha-MCPG) 是一种竞争性和选择性的 I 组/II 组代谢型谷氨酸受体 (mGluR) 拮抗剂。 | ||||
| GC12394 | (±)-trans-ACPD | 67684-64-4 | >98.00% | |
An mGluR agonist | ||||
| GC12485 | Ro 67-7476 | 298690-60-5 | >98.00% / >99.00% / >99.50% | |
A positive allosteric modulator of mGluR1 | ||||
| GC12510 | BINA | 866823-73-6 | >99.00% | |
A positive allosteric modulator of mGluR2 | ||||
| GC12532 | CHPG | 170846-74-9 | >98.00% | |
A potent and selective mGluR5 agonist | ||||
| GC12831 | LY 367385 | 198419-91-9 | >98.00% / >99.00% | |
An antagonist of mGluR1α | ||||