GlpBio

S1P receptor

S1P receptor(S1P受体)

S1P (sphinogosine-1-phosphate) receptor is a G-protein coupled receptor that involved in regulation of cells proliferation, survival, motility and adhesion etc.

S1P receptor 相关产品(8)

  • GC11917 structure
    GC11917PF-543
    CAS: 1415562-82-1
    纯度: >98.00%

    PF-543是一种强效、选择性、可逆和鞘氨醇竞争性SphK 1抑制剂，IC50值为2nM，Ki值为3.6 nM。

  • GC14807 structure
    GC14807Fingolimod (FTY720) HCl
    CAS: 162359-56-0
    纯度: >99.50% / >99.00%

    芬戈莫德(FTY720)是一种免疫抑制剂,通常用于治疗多发性硬化症,也有抗癌作用,可以作为HDACi(组蛋白脱乙酰酶抑制剂)。

  • GC16701 structure
    GC16701SKI II
    CAS: 312636-16-1
    纯度: >99.50% / >98.00%

    An SPHK1 inhibitor

  • GC14360 structure
    GC14360Ozanimod (RPC1063)
    CAS: 1306760-87-1
    纯度: >99.50%

    An S1P 1 and S1P 5 agonist

  • GC16660 structure
    GC16660Ponesimod
    CAS: 854107-55-4
    纯度: >98.00%

    A potent S1P 1 receptor agonist

  • GC42664 structure
    GC42664A-971432
    CAS: 1240308-45-5
    纯度: >98.00%

    A sphingosine-1-phosphate receptor 5 (S1P 5 ) agonist

  • GC50275 structure
    GC50275Ex 26
    CAS: 1233332-37-0

    Ex 26 (S1P1-IN-Ex 26) 是一种有效的选择性 1-磷酸鞘氨醇受体 1 (S1P1) 拮抗剂 (IC50\u003d0.93 nM)。

  • GC17201 structure
    GC17201BAF312 (Siponimod)
    CAS: 1230487-00-9
    纯度: >99.00%

    BAF312 (Siponimod)是一种选择性、口服有效的sphingosine-1-phosphate (S1P)受体激动剂，对S1P1、S1P4和S1P5受体的EC 50 值分别为0.39nM、750nM和0.98nM。