GlpBio

Neuropeptide FF/AF Receptors

Neuropeptide FF/AF Receptors(神经肽 FF/AF 受体)

Neuropeptide Y receptors are a class of G-protein coupled receptors which are activated by the closely related peptide hormones neuropeptide Y, peptide YY and pancreatic polypeptide. These receptors are involved in the control of a diverse set of behavioral processes including appetite, circadian rhythm, and anxiety.

Neuropeptide Y (NPY) is a potent orexigenic neuropeptide, and antagonism of NPY Y1 and NPY Y5 receptors (NPYxR) is considered a potentially important anti-obesity drug target.

Neuropeptide Y (NPY) is widely distributed in the human body and contributes to a vast number of physiological processes. A number of other uses for modulators of NPY receptors have been implied in a range of diseases.

Neuropeptide FF/AF Receptors 相关产品(49)

  • GA20195 structure
    GA20195(Gly¹,Ser³·²²,Gln⁴·³⁴,Thr⁶,Arg¹⁹,Tyr²¹,Ala²³·³¹,Aib³²)-Pancreatic Polypeptide (human)
    CAS: 313988-89-5

    (Gly¹,Ser³.²²,Gln⁴.³⁴,Thr⁶,Arg¹⁹,Tyr²¹,Ala²³.³¹,Aib³²)-Pancreatic Polypeptide (human)是一种有效的选择性神经肽 Y Y5 受体激动剂，与 hY5 受体结合的 IC50 为 0.24 nM。

  • GA20229 structure
    GA20229(Leu³¹,Pro³⁴)-Neuropeptide Y (human, rat)
    CAS: 132699-73-1

    (Leu³¹,Pro³⁴)-Neuropeptide Y (human, rat) 是一种特异性的神经肽 Y Y1 受体激动剂。

  • GA23511 structure
    GA23511Spexin
    CAS: 1370290-58-6
    纯度: >98.00%

    Spexin是一种保守的肽，起神经递质/神经调节剂和内分泌因子的作用。

  • GC10167 structure
    GC10167CGP 71683 hydrochloride
    CAS: 192322-50-2
    纯度: >99.00%

    An antagonist of NPY receptor Y 5

  • GC10862 structure
    GC10862Galanin (1-30) (human)
    CAS: 119418-04-1
    纯度: >98.00%

    Galanin (1-30) (human) 是一种 30 个氨基酸的神经肽，作为\u200b\u200b GalR1 和 GalR2 受体的激动剂，Kis 均为 1 nM。

  • GC12648 structure
    GC12648Neuropeptide FF
    CAS: 99566-27-5
    纯度: >99.50%

    A neuropeptide and agonist of NPFF1 and NPFF2 receptors

  • GC13167 structure
    GC13167Pancreatic Polypeptide (human)
    CAS: 75976-10-2
    纯度: >99.50%

    An NPY receptor agonist

  • GC13801 structure
    GC13801M40
    CAS: 143896-17-7

    M40，一种多肽性甘丙肽拮抗剂，是一种29个氨基酸的神经肽，广泛分布于大鼠和人的中枢神经系统。

  • GC13864 structure
    GC13864Neuropeptide SF (mouse, rat)
    CAS: 230960-31-3

    Neuropeptide SF (mouse,rat) 是一种有效的神经肽 FF 受体激动剂，对 NPFF1 和 NPFF2 的 Ki 值分别为 48.4 nM 和 12.1 nM。

  • GC14112 structure
    GC14112RFRP 3 (human)
    CAS: 311309-27-0
    纯度: >98.50%

    RFRP-3 (Neuropeptide VF(124-131))(human) 是一种人类 GnIH 肽同源物，是一种通过抑制 Ca2+ 动员来有效抑制促性腺激素分泌的抑制剂。

  • GC14430 structure
    GC14430JNJ 5207787
    CAS: 683746-68-1

    An antagonist of NPY receptor Y 2

  • GC14612 structure
    GC14612JNJ-31020028
    CAS: 1094873-14-9
    纯度: >98.00%

    An antagonist of NPY receptor Y 2

  • GC14881 structure
    GC14881BMS 193885
    CAS: 679839-66-8
    纯度: >99.00%

    Competitive NPY Y1 receptor antagonist

  • GC15408 structure
    GC15408Neuropeptide AF (human)
    CAS: 192387-38-5

    Neuropeptide AF（人）是一种内源性抗阿片肽。

  • GC15469 structure
    GC15469RF 9
    CAS: 876310-60-0
    纯度: >98.50%

    An NPFF receptor antagonist

  • GC15633 structure
    GC15633Neuropeptide SF (human)
    CAS: 192387-39-6

    Endogenous antiopiate neuropeptide

  • GC16987 structure
    GC16987L-152,804
    CAS: 6508-43-6
    纯度: >99.50%

    L-152,804 是一种具有口服活性的选择性神经肽 Y Y5 受体 (NPY5-R) 拮抗剂，对 hY5 的 Ki 值为 26 nM。

  • GC17307 structure
    GC17307CYM 9484
    CAS: 1383478-94-1
    纯度: >99.00%

    CYM 9484 是一种选择性和高效的神经肽 Y (NPY) Y2 受体拮抗剂，IC50 值为 19 nM。

  • GC17424 structure
    GC17424BIIE 0246
    CAS: 246146-55-4

    BIIE 0246 是一种有效且高度选择性的非肽神经肽 Y (NPY) Y2 受体拮抗剂，IC50 为 15 nM。

  • GC30452 structure
    GC30452Peptide YY (PYY), human
    CAS: 118997-30-1
    纯度: >97.00%

    Peptide YY (PYY), human是由肠道L细胞分泌的一种肽类激素。

  • GC30456 structure
    GC30456Pancreatic Polypeptide, bovine
    CAS: 179986-89-1

    PancreaticPolypeptide,bovine是由36个氨基酸组成的直链多肽，由胰腺中产生，能够抑制由分泌素和胆囊素诱导的胰腺分泌。PancreaticPolypeptide,bovine是神经肽(NPY)受体激动剂，对NPYR4有很高的亲和性。

  • GC30721 structure
    GC30721FR252384
    CAS: 447405-11-0

    FR252384是一种有效的neuropeptideY-Y5receptor拮抗剂，IC50值为2.3nM。

  • GC30931 structure
    GC30931Galantide
    CAS: 138579-66-5
    纯度: >99.00%

    Galantide是一种可逆的非特异性甘丙肽受体拮抗剂。

  • GC30947 structure
    GC30947Galanin (1-16), mouse, porcine, rat
    CAS: 125118-77-6

    Galanin(1-16),mouse,porcine,rat是一种甘丙肽(galanin)受体激动剂，Kd值为3nM。