Galanin (1-30) (human)

目录号: GC10862纯度: >98.00%同义词: 甘丙肽
Galanin (1-30) (human) 是一种 30 个氨基酸的神经肽,作为\u200b\u200b GalR1 和 GalR2 受体的激动剂,Kis 均为 1 nM。

Galanin (1-30) (human)
Cas No.: 119418-04-1
规格价格库存数量操作
1mg¥2,520.00现货
1
5mg¥9,900.00现货
1
500µg¥1,530.00现货
1

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产品描述 Description

Galanin (1-30), human is a 30-amino acid neuropeptide, and acts as an agonist of GalR1 and GalR2 receptors, with Kis of both 1 nM.

Galanin (1-30), human (Gal1-30) is an agonist of GalR1 and GalR2 receptors, with Kis of both 1 nM[1]. Galanin (1-30), human displaces 125I-labeled rat galanin with a Kd of 0.5 nM. Galanin (1-30), human (hGal) causes contractions of isolated longitudinal rat fundus strips, with an ED50 of 13.8 ± 1.6 nM[2].

References:
[1]. Hua XY, et al. Galanin acts at GalR1 receptors in spinal antinociception: synergy with morphine and AP-5. J Pharmacol Exp Ther. 2004 Feb;308(2):574-82.
[2]. Schmidt WE, et al. Isolation and primary structure of pituitary human galanin, a 30-residue nonamidated neuropeptide. Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11435-9.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
119418-04-1
同义词
甘丙肽
化学名
(2S,3Z,5S,6Z,8S,9Z,12Z,14S,15Z,17S,18Z,20S)-17-(4-aminobutyl)-20-((Z)-((1Z,3S,4Z,6S,7Z,9S,10Z,13Z,15S,16Z,18S,19Z,21S,22Z,24S,25Z,27S,28Z,30S)-3,18-bis((1H-imidazol-5-yl)methyl)-1-((S)-1-((3Z,5S,6Z,8S,9Z,11S,12Z,15Z,17S,18Z,20S,21Z,23S,24Z,26S,27Z,29S,30Z
SMILES
CC(C[C@@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/C/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/CN)([H])CC1=CNC2=CC=CC=C12)([H])[C@@](O)([H])C)([H])CC(C)C)([H])CC(O)=N)([H])CO)([H])C)([H])CC3=CC=C(O)C=C3)([H])CC(C)C)([H]
分子式
C139H210N42O43
分子量
3157.41 g/mol
溶解性
Soluble to 0.50 mg/ml in Water
保存条件
-20°C, protect from light
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至 37°C,然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备 RT,或根据请求配备蓝冰。

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g/mol