GlpBio

Cholecystokinin Receptor

Cholecystokinin Receptor(胆囊收缩素受体)

Cholecystokinin (CCK) is a neuropeptide that affects growth rate in chickens by regulating appetite. CCK peptides exert their function by binding to two identified receptors, CCKAR and CCKBR in the GI tract and the brain, respectively, as well as in other organs. In mammals, CCK/CCKAR interactions affect a number of immunological parameters, including regulation of lymphocytes and functioning of monocytes.

CCK, also known as pancreozymin, is synthesized and secreted by enteroendocrine cells in the duodenum. The main function of CCK is to cause the release of digestive enzymes and bile from the pancreas and gallbladder, respectively. It also induces drug tolerance to opioids like morphine and heroin. Cholecystokinin (CCK) has strong bioactivity in the regulation of a number of cell activities.

Cholecystokinin Receptor 相关产品(25)

  • GA21898 structure
    GA21898Gastrin I (rat)
    CAS: 81123-06-0

    胃泌素I（大鼠）（Rat Gastrin-17）是一种肽类激素，能有效刺激胃酸分泌。

  • GC10360 structure
    GC10360Lorglumide (sodium salt)
    CAS: 1021868-76-7
    纯度: >99.50%

    A selective antagonist of CCK 1

  • GC11012 structure
    GC11012Proglumide sodium salt
    CAS: 99247-33-3
    纯度: >99.50%

    Proglumide sodium salt 是一种非肽类和具有口服活性的胆囊收缩素 (CCK)-A/B 受体拮抗剂。

  • GC14258 structure
    GC14258SR 27897
    CAS: 136381-85-6
    纯度: >99.00%

    A nonpeptide CCK 1 antagonist

  • GC15133 structure
    GC15133Gastrin I (human)
    CAS: 10047-33-3
    纯度: >99.50%

    Gastrin I (human) 是存在于胃内的内源性肽，作用于缩胆囊素受体2，促进胃酸分泌。

  • GC18139 structure
    GC18139Devazepide
    CAS: 103420-77-5
    纯度: >98.50%

    Devazepide (L-364,718) 是一种有效、竞争性、选择性和口服活性的胆囊收缩素 (CCK) 受体非肽拮抗剂，对大鼠胰腺、牛胆囊和豚鼠脑 CCK 受体的 IC50 分别为 81 pM、45 pM 和 245 nM .

  • GC19258 structure
    GC19258Nastorazepide
    CAS: 209219-38-5
    纯度: >99.50%

    Nastorazepide (Z-360) 是一种选择性的口服 1,5-苯二氮卓衍生物胃泌素/胆囊收缩素 2 (CCK-2) 受体拮抗剂，具有潜在的抗肿瘤活性。

  • GC30008 structure
    GC30008Ceruletide (Caerulein)
    CAS: 17650-98-5
    纯度: >99.50%

    Ceruletide 作为一种十肽和一种有效的胆囊收缩剂，对人类和动物的胆囊肌肉和胆管具有直接的痉挛作用。

  • GC30674 structure
    GC30674CHEMBL333994 (FK-480)
    CAS: 167820-10-2

    CHEMBL333994 (FK-480) 是一种有效的口服有效的胆囊收缩素 A (CCK-A) 拮抗剂，IC50 为 0.67 nM。

  • GC30680 structure
    GC30680Gastrin/CCK antagonist 1
    CAS: 162271-52-5

    Gastrin/CCKantagonist1是gastrin/CCK的拮抗剂，可用于肠胃失调疾病的研究。

  • GC30752 structure
    GC30752CCK-B Receptor Antagonist 1
    CAS: 168161-71-5
    纯度: >99.00%

    CCK-B Receptor Antagonist 1 是胆囊收缩素 B (CCK-B) 受体的拮抗剂，具有减少胃酸分泌的潜力。

  • GC31382 structure
    GC31382Loxiglumide (CR-1505)
    CAS: 107097-80-3
    纯度: >98.00%

    A CCK receptor antagonist

  • GC31407 structure
    GC31407Sograzepide (Netazepide)
    CAS: 155488-25-8
    纯度: >98.00%

    Sograzepide (Netazepide)是一种口服活性高、选择性强且效力强的胃泌素/CCK-B拮抗剂，IC 50 值为 0.1nM，对胃泌素/CCK-A活性具有抑制作用，IC 50 为502nM。

  • GC31477 structure
    GC31477Tarazepide
    CAS: 141374-81-4

    Tarazepide是一种有效且特异性的CCK-A受体拮抗剂。

  • GC31558 structure
    GC31558CCK-A receptor inhibitor 1
    CAS: 137004-80-9

    CCK-Areceptorinhibitor1是一种缩胆囊素A(cholecystokininA,CCK-A)受体抑制剂，IC50为340nM。

  • GC31592 structure
    GC31592GI 181771
    CAS: 305366-98-7

    GI181771是研究用于治疗肥胖症的胆囊收缩素1(cholecystokinin1)受体激动剂。

  • GC31613 structure
    GC31613SR 146131
    CAS: 221671-61-0
    纯度: >98.00%

    SR146131是一种有效，有口服活性，选择性的非多肽缩胆囊素1(cholecystokinin1)受体激动剂。

  • GC32776 structure
    GC32776Pentagastrin (ICI-50123)
    CAS: 5534-95-2
    纯度: >98.00%

    A CCK 2 receptor agonist

  • GC35846 structure
    GC35846Dexloxiglumide
    CAS: 119817-90-2
    纯度: >98.00%

    A CCK 1 receptor antagonist

  • GC36610 structure
    GC36610Mini Gastrin I, human
    CAS: 54405-27-5

    Mini Gastrin I, human 为由 13 个氨基酸组成的短的人胃泌素 (gastrin)。

  • GC36611 structure
    GC36611Mini Gastrin I, human TFA
    纯度: >98.00%

    Mini Gastrin I, human (TFA) 为由 13 个氨基酸组成的短的人胃泌素 (gastrin)。

  • GC36976 structure
    GC36976Proglumide
    CAS: 6620-60-6
    纯度: >99.00%

    Proglumide 是已知的胆囊收缩素 (CCK) 拮抗剂。

  • GC38746 structure
    GC38746CCK-B Receptor Antagonist 2
    CAS: 155412-88-7
    纯度: >98.50%

    CCK-B Receptor Antagonist 2，化合物 15b，是有效的口服活性 Gastrin/CCK-B 拮抗剂，IC50 值为 0.43 nM。 CCK-B Receptor Antagonist 2 还抑制 Gastrin/CCK-A 活性，IC50 为 1.82 μM。

  • GC70264 structure
    GC70264L-365260 hemihydrate
    纯度: >99.00%

    L-365260 hemihydrate是非肽胃泌素和脑胆囊收缩素受体(CCK-B)的口服选择性活性拮抗剂，Kis分别为1.9 nM和2.0 nM。