GPCR/G protein
GPCR/G protein(G 蛋白偶联受体/G 蛋白)
- Neuropeptide FF/AF Receptors(49)
- Formyl Peptide Receptors(11)
- 5-HT Receptor(504)
- Acetylcholine(29)
- Adenosine Deaminase(9)
- Adenosine Receptor(132)
- Adenosine Kinase(4)
- Adiponectin Receptor(3)
- Adrenergic Receptor(421)
- Adrenergic Transporters(5)
- Apelin Receptor(9)
- Angiotensin Receptor(114)
- Bombesin Receptors(23)
- Bradykinin Receptors(29)
- Calcitonin and Related Receptors(10)
- Cannabinoid Receptor(160)
- Calcimimetic Agent(2)
- CaSR(20)
- CCK1 Receptors(7)
- CCK2 Receptors(7)
- CCR(81)
- Chemokine Receptors(25)
- CRF1 Receptors(9)
- CRF2 Receptors(3)
- CXCR(80)
- CysLT1 receptor(1)
- Endothelin Receptor(52)
- EP1 Receptor(2)
- EP4 Receptor(3)
- ERRγ(1)
- ETA Receptors(5)
- ETB Receptors(5)
- Free Fatty Acid Receptors(18)
- Galanin Receptors(11)
- Ghrelin Receptors(12)
- GHSR(21)
- GIP Receptor(5)
- Glucagon Receptor(61)
- Glucocorticoid Receptor(97)
- GLUT1(1)
- Gonadotropin-Releasing Hormone Receptors(3)
- GPCR19(12)
- GPR109A(4)
- GPR119(10)
- GPR120(9)
- GPR35(10)
- GPR44(1)
- GPR55(11)
- Hydroxycarboxylic Acid Receptors(5)
- Leukotriene Receptor(58)
- LPA Receptor(12)
- LPL Receptor(60)
- LTD4 Receptor(1)
- mGluR (119)
- Melanin-concentrating Hormone Receptors(7)
- Melanocortin (MC) Receptors(58)
- Melatonin Receptors(24)
- Motilin Receptor(7)
- MT Receptor(1)
- Non-selective CRF(7)
- Neurotensin Receptors(24)
- NK2 Receptors(7)
- NK3 Receptor(6)
- NOP Receptor(20)
- NPY Receptors(28)
- Orexin(3)
- Orphan 7-TM Receptors(6)
- OX Receptor(48)
- Oxytocin Receptors(22)
- P2Y Receptor(62)
- PACAP Receptors(3)
- PAF Receptors(8)
- Peptide Receptors(14)
- PGD2 Receptor(1)
- Prostaglandin Receptor(172)
- Protease-Activated Receptors(10)
- Prostanoid Receptors
- RGS(2)
- S1P receptor(8)
- Secretin Receptors(1)
- Sensory Neuron-Specific Receptors(1)
- Somatostatin Receptor(39)
- Sigma Receptor(59)
- Vasopressin Receptor(35)
- 17,20-lyase(5)
- Ras(142)
- Urotensin-II Receptor(11)
- VIP Receptors(7)
- EBI2/GPR183(7)
- TSH Receptor(11)
- NK Receptor(1)
- GPR81(1)
- C3aR(1)
- CysLT2 receptor(1)
- S1P receptor inhibitor(22)
- CCKB(1)
- FFAR1 (GPR40)(20)
- GPR84(8)
- Neuromedin U Receptors(2)
- Kisspeptin Receptor(5)
- CRFR(25)
- RGS Protein(5)
- Urotensin Receptor(6)
- Cholecystokinin Receptor(25)
- GPR139(4)
- mAChR(185)
- MCHR1 (GPR24)(16)
- Neurokinin Receptor(75)
- Neuropeptide S Receptor(1)
- GPBA Receptor(1)
- Trace Amine 1 Receptor(2)
- GPCR protein(1)
- FFAR3(1)
- cGMP(27)
- GRK(1)
- GPR88
- Amylin Receptor
- Arrestin
- GCGR(2)
- GLP Receptor(2)
- Mas-related G-protein-coupled Receptor (MRGPR)
- Succinate Receptor 1
- PTHR(1)
- Protease Activated Receptor (PAR)(2)
- Free Fatty Acid Receptor(1)
- Formyl Peptide Receptor (FPR)(1)
GPCR/G protein 相关产品(3377)
- GC32642Tropodifene (Tropaphen)CAS: 15790-02-0
Tropodifene (Tropaphen) (Tropaphen) 是一种 α-Adrenergic receptor 抑制剂。
- GC32644(4E)-SUN9221CAS: 222318-55-0
(4E)-SUN9221是一种有效的α1-adrenergicreceptor和5-HT2receptor拮抗剂，具有抗高血压和抗血小板聚集的功效。
- GC326555-HT2 antagonist 1CAS: 191592-09-3
5-HT2antagonist1是一种有效的5-HT2receptor拮抗剂，同时对α1adrenoceptor有微弱地抑制作用。
- GC32662Guanoxabenz (Hydroxyguanabenz)CAS: 24047-25-4
Guanabenz (GBZ, GA, Wytensin, Wy-8678,BR-750) is an orally active central alpha 2-adrenoceptor (α2 adrenergic receptor) agonist with antihypertensive action.
- GC326645-HT2A antagonist 1CAS: 204643-75-4
5-HT2Aantagonist1是来自专利US5728835A和JP1007727的5-HT2A拮抗剂。5-HT2Aantagonist1可能用于治疗心血管疾病的研究。
- GC32665Bometolol HydrochlorideCAS: 65023-16-7
BometololHydrochloride是一种beta-adrenergic阻滞剂，可用于高血压等心血管疾病的研究。
- GC32666Timepidium bromide (Sesden)CAS: 35035-05-3
Timepidium bromide (Sesden) (Sesden; SA504) 是一种抗胆碱能药物。
- GC32716Pan-RAS-IN-1CAS: 1835283-94-7纯度: >98.50%
Pan-RAS-IN-1, a pan-Ras inhibitor, binds to KRasG12D-GppNHp with a Kd less than 20 μM in MST, ITC and NMR assays, also binds to Ras proteins and exhibits lethality in cells partially dependent on expression of Ras proteins.
- GC32729Rhosin hydrochlorideCAS: 1281870-42-5纯度: >99.50% / >98.00%
Rhosin hydrochloride是一种有效的、特异性的RhoA亚家族Rho GTPases小分子抑制剂，能够特异性地结合RhoA并抑制RhoA与鸟嘌呤核苷酸交换因子（GEF）的相互作用，其解离常数（Kd）约为0.4μM。
- GC32905Alprenolol ((RS)-Alprenolol)CAS: 13655-52-2纯度: >99.50%
A non-selective β-AR and 5-HT receptor antagonist
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC32642 | Tropodifene (Tropaphen) | 15790-02-0 | - | |
Tropodifene (Tropaphen) (Tropaphen) 是一种 α-Adrenergic receptor 抑制剂。 | ||||
| GC32644 | (4E)-SUN9221 | 222318-55-0 | - | |
(4E)-SUN9221是一种有效的α1-adrenergicreceptor和5-HT2receptor拮抗剂，具有抗高血压和抗血小板聚集的功效。 | ||||
| GC32653 | KF 13218 | 127654-03-9 | - | |
KF13218是一种有效和持久的选择性血栓烷B2(TXB2)合成酶抑制剂，IC50值为5.3±1.3nM。 | ||||
| GC32654 | Relacorilant (CORT 125134) | 1496510-51-0 | - | |
Relacorilant (CORT 125134)是一种有效的糖皮质激素受体（GR）拮抗剂。 | ||||
| GC32655 | 5-HT2 antagonist 1 | 191592-09-3 | - | |
5-HT2antagonist1是一种有效的5-HT2receptor拮抗剂，同时对α1adrenoceptor有微弱地抑制作用。 | ||||
| GC32662 | Guanoxabenz (Hydroxyguanabenz) | 24047-25-4 | - | |
Guanabenz (GBZ, GA, Wytensin, Wy-8678,BR-750) is an orally active central alpha 2-adrenoceptor (α2 adrenergic receptor) agonist with antihypertensive action. | ||||
| GC32664 | 5-HT2A antagonist 1 | 204643-75-4 | - | |
5-HT2Aantagonist1是来自专利US5728835A和JP1007727的5-HT2A拮抗剂。5-HT2Aantagonist1可能用于治疗心血管疾病的研究。 | ||||
| GC32665 | Bometolol Hydrochloride | 65023-16-7 | - | |
BometololHydrochloride是一种beta-adrenergic阻滞剂，可用于高血压等心血管疾病的研究。 | ||||
| GC32666 | Timepidium bromide (Sesden) | 35035-05-3 | - | |
Timepidium bromide (Sesden) (Sesden; SA504) 是一种抗胆碱能药物。 | ||||
| GC32667 | Nuvenzepine | 96487-37-5 | >99.00% | |
Nuvenzepine是mAChR的拮抗剂，之前在临床一期试验中用来治疗胃痉挛。 | ||||
| GC32670 | L-765314 | 189349-50-6 | >99.50% | |
L-765314 is a selective and potent α1b-adrenoceptor (α1b adrenergic receptor) antagonist with an IC50 of 1.90 nM and Kis of 5.4 and 2.0 for rat and human α1b adrenergic receptor, respectively. | ||||
| GC32674 | A81988 (Abbott81988) | 141887-34-5 | - | |
A81988 (Abbott81988) 是一种有效的、竞争性的、非肽类血管紧张素 AT1 受体拮抗剂。 | ||||
| GC32675 | GP531 | 142344-87-4 | >98.50% | |
GP531是一种有效的第二代腺苷(adenosine)调节剂，在基础条件下药理学沉默，但在缺血期间增加局部内源性腺苷。 | ||||
| GC32707 | AZD-5069 | 878385-84-3 | >99.50% | |
A CXCR2 antagonist | ||||
| GC32716 | Pan-RAS-IN-1 | 1835283-94-7 | >98.50% | |
Pan-RAS-IN-1, a pan-Ras inhibitor, binds to KRasG12D-GppNHp with a Kd less than 20 μM in MST, ITC and NMR assays, also binds to Ras proteins and exhibits lethality in cells partially dependent on expression of Ras proteins. | ||||
| GC32729 | Rhosin hydrochloride | 1281870-42-5 | >99.50% / >98.00% | |
Rhosin hydrochloride是一种有效的、特异性的RhoA亚家族Rho GTPases小分子抑制剂，能够特异性地结合RhoA并抑制RhoA与鸟嘌呤核苷酸交换因子（GEF）的相互作用，其解离常数（Kd）约为0.4μM。 | ||||
| GC32734 | CPI-444 (V81444) | 1202402-40-1 | >98.00% | |
An adenosine A 2A receptor antagonist | ||||
| GC32742 | INT-767 | 1000403-03-1 | >98.00% | |
INT-767是一种强效的法尼醇X受体（FXR）和Takeda G蛋白偶联受体5（TGR5）双重激动剂，EC 50 值分别为30nM和630nM。 | ||||
| GC32749 | Sincalide (CCK-8) | 25126-32-3 | - | |
辛卡利特(CCK-8)是CCK的一个次要生物活性片段，保留了CCK的大部分生物活性，被广泛用于研究CCK的功能。 | ||||
| GC32770 | 1A-116 | 1430208-73-3 | >99.00% | |
1A-116 is a Rac1 inhibitor, with antitumoral and antimetastatic effects in several types of cancer, such as breast cancer, prevents Rac1-regulated processes involved in the primary tumorigenesis and metastastic processes. | ||||
| GC32776 | Pentagastrin (ICI-50123) | 5534-95-2 | >98.00% | |
A CCK 2 receptor agonist | ||||
| GC32821 | Noscapine ((S,R)-Noscapine) | 128-62-1 | - | |
Noscapine是一种口服止咳药,主要通过其σ受体激动剂活性调节,且Noscapine具有抗癌活性。 | ||||
| GC32905 | Alprenolol ((RS)-Alprenolol) | 13655-52-2 | >99.50% | |
A non-selective β-AR and 5-HT receptor antagonist | ||||
| GC32970 | MBQ-167 | 2097938-73-1 | >98.00% | |
MBQ-167是Ras相关的C3型肉毒素底物(Rac)和细胞分裂周期蛋白(Cdc42)的双抑制剂，其对Rac1/2/3的IC50值为103nM，对Cdc42的IC50值为78nM。 | ||||