GlpBio

Timepidium bromide (Sesden)

目录号: GC32666纯度: >98%同义词: 噻哌溴铵,Sesden; SA504
COASDSData Sheet
Timepidium bromide (Sesden) (Sesden; SA504) 是一种抗胆碱能药物。
Timepidium bromide (Sesden)
Cas No.: 35035-05-3
规格价格库存数量操作
1mg¥3,570.00现货
1
5mg¥7,140.00现货
1
10mg¥12,138.00现货
1
20mg¥21,420.00现货
1
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文献被引

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产品描述 Description

Timepidium bromide (Sesden; SA504) is an anticholinergic agent.

Effects of Timepidium bromide (TB), acetylcholine (ACh) and neostigmine (Neost) on gastric and duodenal blood flow distribution are studied by the use of 131I-labeled macroaggregated human serum albumin (MAA) in rabbits. In normal rabbits, gastric blood flow is found to be uneven in various regions of the stomach: anterior corpus (50% of total gastric blood flow) greater than posterior corpus (40%) greater than pyloric antrum (7%). Intravenous administration of Timepidium bromide (200 μg/kg) to normal rabbits produces a slight increase in total gastric blood flow, but the increase in the mucosal layer of the pyloric antrum is considerable[1].

[1]. Naito K, et al. Effect of timepidium bromide, an anticholinergic agent, on gastric and duodenal blood flow distribution in rabbits. Jpn J Pharmacol. 1982 Feb;32(1):73-80.

实验参考方法 Experimental Reference Method

Animal experiment:

Rabbits[1]Timepidium bromide (200 μg/kg) is injected into the femoral vein 5 min prior to 131I-MAA. To evaluate the effects of Timepidium bromide on gastric and duodenal blood flow in cholinergic drug-treated animals, Timepidium bromide is administered in a dose of 200 μg/kg through the femoral vein 3 min before ACh or 5 min after Neost. 131I-MAA is given into the left ventricle of the animals 2 min after ACh and 10 min after Neost.

References:

[1]. Naito K, et al. Effect of timepidium bromide, an anticholinergic agent, on gastric and duodenal blood flow distribution in rabbits. Jpn J Pharmacol. 1982 Feb;32(1):73-80.

产品文档 Product Documents

Purity:>98%
COASDSData Sheet

化学性质Chemical Properties

CAS 号
35035-05-3
同义词
噻哌溴铵,Sesden; SA504
SMILES
C[N+]1(C)C/C(CC(OC)C1)=C(C2=CC=CS2)\C3=CC=CS3.[Br-]
分子式
C17H22BrNOS2
分子量
400.4 g/mol
溶解性
Soluble in DMSO
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol