GPCR/G protein

GPCR/G protein(G 蛋白偶联受体/G 蛋白)

研究方向

GPCR/G protein 相关产品(3377)

GC19389 YL0919
CAS: 1339058-04-6
纯度: >99.50%
YL0919 (YL0919) 是一种具有双重活性的口服抗抑郁药，作为高度选择性的 5-HT 摄取阻滞剂和有效的 5-HT1Areceptor 激动剂 (Ki=0.19 nM)。
GC19395 MK-7246
CAS: 1218918-62-7
纯度: >98.50%
A CRTH 2 /DP 2 receptor antagonist
GC19413 MK-5046
CAS: 1022152-70-0
纯度: >99.50% / >99.00%
MK-5046是一种强效，具有选择性和口服活性的Bombesin受体亚型3（BRS-3）激动剂，对hBRS-3的IC 50 和EC 50 值分别为27nM和25nM。
GC19441 Levocabastine (hydrochloride)
CAS: 79547-78-7
纯度: >98.00%
A histamine H 1 receptor antagonist
GC19486 LIT-927
CAS: 2172879-52-4
LIT-927是一种能有效抑制C-X-C趋化因子12（CXCL12）与受体CXCR4相互作用，且具有高效选择性和口服活性的CXCL12中和配体，结合亲和力K i 值为267nM。
GC19502 BAY-545
CAS: 1699717-32-2
An adenosine A 2B receptor antagonist
GC19541 (rac)-Antineoplaston A10
CAS: 77658-84-5
(rac)-Antineoplaston A10 是 Antineoplaston A10 的外消旋体。 Antineoplaston A10 是一种潜在的 Ras 抑制剂，可用于治疗神经胶质瘤、淋巴瘤、星形细胞瘤和乳腺癌。
GC19543 NCGC00379308
CAS: 662164-09-2
NCGC00379308 是促甲状腺激素受体 (TSHR) 的正变构调节剂，它通过直接激活 TSHR 启动 β-Arr 1 的易位，并在体外增强 TSH 介导的前成骨细胞分化。
GC19630 Adenosine 2′-monophosphate
CAS: 130-49-4
腺苷 &2#8242;-一磷酸 (2'-AMP) 被细胞外 2',3'-CAMP 转化。
GC25046 Albiglutide Fragment
CAS: 782500-75-8
纯度: >98.00%
Albiglutide fragment is one copy of a 30-amino-acid sequence of modified human GLP-1 (fragment 7-36).
GC25051 Alloxazine
CAS: 490-59-5
Alloxazine (Isoalloxazine) is an A2 receptor antagonist, which is approximately 10-fold more selective for the A2B receptor than for the A2A receptor.
GC25120 Balixafortide (POL6326)
CAS: 1051366-32-5
Balixafortide (POL6326) is an orally bioavailable peptidic CXC chemokine receptor 4 (CXCR4) antagonist
GC25140 Bisoprolol
CAS: 66722-44-9
Bisoprolol is a cardioselective β1-adrenergic blocking agent used for secondary prevention of myocardial infarction (MI), heart failure, angina pectoris and mild to moderate hypertension.
GC25197 Carvedilol EP IMpurity E
CAS: 64464-07-9
Carvedilol is a nonselective beta blocker/alpha-1 blocker and used in management of congestive heart failure (CHF).
GC25253 Cinitapride Hydrogen Tartrate
CAS: 1207859-16-2
Cinitapride Hydrogen Tartrate is a gastroprokinetic agent that acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors
GC25259 Cisapride hydrate
CAS: 260779-88-2
Cisapride (Propulsid, Alimix, Propulsin, Enteropride, Kinestase) acts directly as a selective serotonin 5-HT4 receptor agonist with IC50 of 0.483 μM. And It also acts indirectly as a parasympathomimetic.
GC25385 Esmolol
CAS: 81147-92-4
Esmolol is a cardioselective beta1 receptor blocker with rapid onset, a very short duration of action, and no significant intrinsic sympathomimetic or membrane stabilising activity at therapeutic dosages.
GC25412 Fenoterol
CAS: 13392-18-2
纯度: >98.00% / >99.50%
Fenoterol (Phenoterol) is a β2 adrenoreceptor agonist with bronchodilator activity.
GC25434 Frovatriptan Succinate
CAS: 158930-09-7
Frovatriptan Succinate(SB 209509 Succinate,VML 251 Succinate) is the succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity especially for the 5-HT1B/1D receptors.
GC25484 Guanabenz
CAS: 5051-62-7
Guanabenz (GBZ, GA, Wytensin, Wy-8678,BR-750) is an orally active central alpha 2-adrenoceptor (α2 adrenergic receptor) agonist with antihypertensive action.
GC25563 Lasmiditan succinate
CAS: 439239-92-6
Lasmiditan succinate (COL-144, LY573144) is a novel, centrally acting, highly selective 5-HT(1F) receptor agonist (Ki=2.21 nM) without vasoconstrictor activity.
GC25569 Lerisetron
CAS: 143257-98-1
Lerisetron (F 0930, F 0930RS) is a 5-HT3 receptor antagonist with IC50 of 0.81μM.
GC25618 Maropitant citrate
CAS: 359875-09-5
Maropitant citrate is a novel neurokinin type-1 (NK1) receptor antagonist with anti-inflammatory and analgesic properties
GC25663 Nebivolol
CAS: 118457-14-0
Nebivolol (Bystolic,R 065824) is a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect used in treatment of hypertension and also for left ventricular failure.

分类产品列表
货号	产品名称	CAS号	纯度
GC19389	YL0919	1339058-04-6	>99.50%
GC19389	YL0919 (YL0919) 是一种具有双重活性的口服抗抑郁药，作为高度选择性的 5-HT 摄取阻滞剂和有效的 5-HT1Areceptor 激动剂 (Ki=0.19 nM)。
GC19395	MK-7246	1218918-62-7	>98.50%
GC19395	A CRTH 2 /DP 2 receptor antagonist
GC19413	MK-5046	1022152-70-0	>99.50% / >99.00%
GC19413	MK-5046是一种强效，具有选择性和口服活性的Bombesin受体亚型3（BRS-3）激动剂，对hBRS-3的IC 50 和EC 50 值分别为27nM和25nM。
GC19441	Levocabastine (hydrochloride)	79547-78-7	>98.00%
GC19441	A histamine H 1 receptor antagonist
GC19486	LIT-927	2172879-52-4	-
GC19486	LIT-927是一种能有效抑制C-X-C趋化因子12（CXCL12）与受体CXCR4相互作用，且具有高效选择性和口服活性的CXCL12中和配体，结合亲和力K i 值为267nM。
GC19502	BAY-545	1699717-32-2	-
GC19502	An adenosine A 2B receptor antagonist
GC19541	(rac)-Antineoplaston A10	77658-84-5	-
GC19541	(rac)-Antineoplaston A10 是 Antineoplaston A10 的外消旋体。 Antineoplaston A10 是一种潜在的 Ras 抑制剂，可用于治疗神经胶质瘤、淋巴瘤、星形细胞瘤和乳腺癌。
GC19543	NCGC00379308	662164-09-2	-
GC19543	NCGC00379308 是促甲状腺激素受体 (TSHR) 的正变构调节剂，它通过直接激活 TSHR 启动 β-Arr 1 的易位，并在体外增强 TSH 介导的前成骨细胞分化。
GC19630	Adenosine 2′-monophosphate	130-49-4	-
GC19630	腺苷 &2#8242;-一磷酸 (2'-AMP) 被细胞外 2',3'-CAMP 转化。
GC25046	Albiglutide Fragment	782500-75-8	>98.00%
GC25046	Albiglutide fragment is one copy of a 30-amino-acid sequence of modified human GLP-1 (fragment 7-36).
GC25051	Alloxazine	490-59-5	-
GC25051	Alloxazine (Isoalloxazine) is an A2 receptor antagonist, which is approximately 10-fold more selective for the A2B receptor than for the A2A receptor.
GC25120	Balixafortide (POL6326)	1051366-32-5	-
GC25120	Balixafortide (POL6326) is an orally bioavailable peptidic CXC chemokine receptor 4 (CXCR4) antagonist
GC25140	Bisoprolol	66722-44-9	-
GC25140	Bisoprolol is a cardioselective β1-adrenergic blocking agent used for secondary prevention of myocardial infarction (MI), heart failure, angina pectoris and mild to moderate hypertension.
GC25197	Carvedilol EP IMpurity E	64464-07-9	-
GC25197	Carvedilol is a nonselective beta blocker/alpha-1 blocker and used in management of congestive heart failure (CHF).
GC25253	Cinitapride Hydrogen Tartrate	1207859-16-2	-
GC25253	Cinitapride Hydrogen Tartrate is a gastroprokinetic agent that acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors
GC25259	Cisapride hydrate	260779-88-2	-
GC25259	Cisapride (Propulsid, Alimix, Propulsin, Enteropride, Kinestase) acts directly as a selective serotonin 5-HT4 receptor agonist with IC50 of 0.483 μM. And It also acts indirectly as a parasympathomimetic.
GC25385	Esmolol	81147-92-4	-
GC25385	Esmolol is a cardioselective beta1 receptor blocker with rapid onset, a very short duration of action, and no significant intrinsic sympathomimetic or membrane stabilising activity at therapeutic dosages.
GC25412	Fenoterol	13392-18-2	>98.00% / >99.50%
GC25412	Fenoterol (Phenoterol) is a β2 adrenoreceptor agonist with bronchodilator activity.
GC25434	Frovatriptan Succinate	158930-09-7	-
GC25434	Frovatriptan Succinate(SB 209509 Succinate,VML 251 Succinate) is the succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity especially for the 5-HT1B/1D receptors.
GC25484	Guanabenz	5051-62-7	-
GC25484	Guanabenz (GBZ, GA, Wytensin, Wy-8678,BR-750) is an orally active central alpha 2-adrenoceptor (α2 adrenergic receptor) agonist with antihypertensive action.
GC25563	Lasmiditan succinate	439239-92-6	-
GC25563	Lasmiditan succinate (COL-144, LY573144) is a novel, centrally acting, highly selective 5-HT(1F) receptor agonist (Ki=2.21 nM) without vasoconstrictor activity.
GC25569	Lerisetron	143257-98-1	-
GC25569	Lerisetron (F 0930, F 0930RS) is a 5-HT3 receptor antagonist with IC50 of 0.81μM.
GC25618	Maropitant citrate	359875-09-5	-
GC25618	Maropitant citrate is a novel neurokinin type-1 (NK1) receptor antagonist with anti-inflammatory and analgesic properties
GC25663	Nebivolol	118457-14-0	-
GC25663	Nebivolol (Bystolic,R 065824) is a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect used in treatment of hypertension and also for left ventricular failure.