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Home >> Signaling Pathways >> GPCR/G protein

GPCR/G protein(G 蛋白偶联受体/G 蛋白)

Cat.No. 产品名称 Information
GC14212 BW 245C A selective DP₁ receptor agonist
GC17092 HAMI3379 HAMI3379是首个被报道的强效选择性半胱氨酰白氧合肽（CysLT₂）受体拮抗剂，也被鉴定为孤儿G蛋白偶联受体GPR17的拮抗剂。
GC14177 R-1 Methanandamide Phosphate
R-1MAP,(R)-(+)-Arachidonyl-1'-Hydroxy-2'-Propylamide Phosphate
A water soluble prodrug AEA analog
GC15093 AM4113
AM4113
A CB₁ receptor neutral antagonist
GC16689 3-chloro-5-hydroxy BA
3-氯-5-羟基苯甲酸,3-chloro-5-hydroxy BA,CHBA,GPR81 Agonist
An agonist of GPR81
GC17617 Tetradecyl Phosphonate
N-四癸基磷酸
A stable pan-antagonist at LPA receptors
GC16693 13Z,16Z-Docosadienoic Acid
顺13,16-二十二碳二烯酸,cis-13,16-Docosadienoic Acid
A natural ω-6 PUFA
GC10821 11-keto-β-Boswellic Acid
11-酮基-BETA-乳香酸,11-oxo-β-Boswellic acid,KBA
A 5-LO inhibitor
GC16558 DBIBB A non-lipid agonist of LPA₂
GC14919 Niguldipine (hydrochloride)
B 844-39,NSC 617553
An α_1A-adrenoceptor antagonist
GC15213 SQ 29,548
1S-[1Α,2Β(5Z),3Β,4Α]]-7-[3-[2-(苯氨基甲酰基)肼基甲基]-7-氧代双环[2.2.1]庚-2-基]-5-庚烯酸
A selective TP receptor antagonist
GC17410 S18886
特鲁曲班,Terutroban,Triplion
A TP receptor antagonist
GC17998 Isoxsuprine (hydrochloride)
异舒普林盐酸盐；盐酸异克舒令
An adrenergic receptor modulator
GC10475 Proxyphylline
羟丙茶碱
A methylxanthine derivative and an adenosine receptor antagonist
GC10623 ACS 67 An H₂S-releasing latanoprost analog
GC16566 AL 8810 isopropyl ester A lipid soluble, esterified prodrug of AL 8810
GC18120 XAP044 XAP044是一种mGlu7选择性拮抗剂，IC₅₀值为5.5μM。
GC11100 Flibanserin
氟立班丝氨; BIMT-17; BIMT-17BS
A 5-HT_1A receptor agonist and 5-HT_2A receptor antagonist
GC12778 Clenbuterol (hydrochloride)
盐酸克仑特罗,NAB 365,Ventipulmin
Clenbuterol (hydrochloride)是一种β₂-肾上腺素受体激动剂，EC₅₀为31.9nM。Clenbuterol (hydrochloride)可有效抑制脂多糖（LPS）诱导的TNF-α和IL-1β释放。
GC10032 SR 144528
SR144528
SR 144528是一种高效、选择性且具有口服活性的CB2受体拮抗剂，对 CB2 受体的K_i值为0.6nM。
GC13087 LY171883
油酸三乙醇胺
Selective, potent LTD₄ receptor antagonist
GC14078 MRS1523
An adenosine A₃ receptor antagonist
GC12512 Losartan Carboxylic Acid
氯沙坦羧酸,E-3174,EXP-3174
An active metabolite of losartan
GC17319 L-Phenylephrine
去氧肾上腺素; (R)-(-)-Phenylephrine; L-Phenylephrine
A selective adrenergic α_1A receptor agonist
GC12263 Erythromycin A enol ether
红霉素 A 烯醇醚
A mimic of motilin
GC17526 BKT140
BKT140 (4-fluorobenzoyl); BL-8040; TF14016
A CXCR4 antagonist
GC12362 ONO-7300243 An LPA₁ receptor antagonist
GC14711 ATI-2341
变构激动剂多肽ATI2341
A Gα_i-signaling biased CXCR4 agonist
GC16660 Ponesimod
ACT-128800
A potent S1P₁ receptor agonist
GC12293 Perphenazine
奋乃静
A typical antipsychotic
GC17596 Netupitant
奈妥吡坦; CID 6451149
An NK₁ receptor antagonist
GC12311 Trihexyphenidyl hydrochloride
盐酸苯海索
A muscarinic M₁ receptor antagonist
GC15992 Lu AF21934 A positive allosteric modulator of mGluR4
GC16692 Casin
Pirl1-related Compound 2
A Cdc42 GTPase inhibitor
GC10265 Manumycin A
手霉素A
A farnesyltransferase inhibitor with antitumor activity
GC11004 A 779 A 779是一种有效的选择性血管紧张素-(1-7)/ Mas受体拮抗剂，IC₅₀值为0.3nM。
GC14360 Ozanimod (RPC1063)
奥扎莫德; RPC-1063
An S1P₁ and S1P₅ agonist
GC10743 Cyclobenzaprine HCl
盐酸环苯扎林; MK130 hydrochloride
An Analytical Reference Material
GC16895 AL 8810 A potent, selective FP receptor antagonist
GC16395 Carteolol HCl
盐酸卡替洛尔; OPC-1085 hydrochloride
A β-adrenergic receptor antagonist
GC16820 ELN441958 ELN441958是一种强效、竞争性且选择性的bradykinin B1受体拮抗剂，K_i值为0.26nM。
GC17249 PF-3274167 An oxytocin receptor antagonist
GC15319 Cyclosporin H
环孢菌素H
环孢菌素H（Cyclosporin H）是一种有效的选择性甲酰基肽受体（FPR）拮抗剂，IC₅₀值为0.7μM。
GC15449 Rolapitant
罗拉匹坦; SCH619734
A potent NK₁ receptor antagonist
GC13082 Regadenoson
瑞加德松; CVT-3146
Regadenoson是一种选择性的、具有冠状动脉扩张活性的A2A腺苷受体激动剂。
GC10005 SEP-0372814 A PDE10A inhibitor
GC10075 Methylprednisolone Sodium Succinate
甲基泼尼松龙琥珀酸钠
A prodrug form of methylprednisolone
GC14266 CCG 203971 An inhibitor of the Rho/MKL1/SRF transcriptional pathway
GC12956 ML224
NCGC00242364; ANTAG3
ML224(NCGC00242364; ANTAG3) 是一种选择性 TSHR 反向激动剂；抑制 TSH 刺激的 cAMP 产生，IC50 = 2.3 μM。
GC12795 CCG-1423 An inhibitor of Rho-mediated cell signalling