Proteases
Proteases(蛋白酶)
Proteases, also known as peptidases or proteolytic enzymes, consists of a large number of enzymes catalyzing the hydrolysis of peptide bonds and subsequently resulting in the degradation of protein substrates into amino acids. Proteases are involved in a wide range of human diseases, including cancer, neurodegenerative disorders, inflammatory diseases and cardiovascular diseases. Thus numerous proteases inhibitors (small molecules and proteins) have been identified to block activity of proteases. Proteases inhibitors can be classified into different types based on the class of proteases they inhibit through two general mechanisms, irreversible “trapping” reactions and reversible tight-binding reactions. Proteases inhibitors have been used as diagnostic or therapeutic agents for the treatment of proteases-related diseases.
- Aminopeptidase(21)
- ACE(75)
- Calpains(11)
- Carboxypeptidase(9)
- Cathepsin(65)
- DPP-4(18)
- Elastase(25)
- Gamma Secretase(50)
- HCV Protease(39)
- HSP(105)
- HIV Integrase(30)
- HIV Protease(35)
- MMP(195)
- NS3/4a protease(4)
- Serine Protease(19)
- Thrombin(47)
- Urokinase(2)
- Cysteine Protease
- Tyrosinases(50)
- Other Proteases(15)
- 15-PGDH(1)
- Acetyl-CoA Carboxylase(14)
- Acyltransferase(64)
- Aldehyde Dehydrogenase (ALDH)(30)
- Aminoacyl-tRNA Synthetase(9)
- ATGL(1)
- Dipeptidyl Peptidase(49)
- Drug Metabolite(513)
- E1/E2/E3 Enzyme(92)
- Endogenous Metabolite(1768)
- FABP(9)
- Farnesyl Transferase(20)
- Glutaminase(17)
- Glutathione Peroxidase(35)
- Isocitrate Dehydrogenase (IDH)(28)
- Lactate Dehydrogenase(19)
- Lipoxygenase(274)
- Mitochondrial Metabolism(260)
- NEDD8-activating Enzyme(6)
- Neprilysin(12)
- PAI-1(14)
- Ser/Thr Protease(49)
- Tryptophan Hydroxylase(12)
- Xanthine Oxidase(18)
- MALT1(10)
- Caspase(117)
- PCSK9(13)
- ADAMTS(1)
- Density Lipoprotein
- TrxR(1)
- DGK(3)
Proteases 相关产品(4079)
- GN10494Astragaloside IVCAS: 84687-43-4纯度: >98.00%
Astragaloside IV是黄芪中提取的一种有效成分，可减轻心肌缺血/再灌注损伤，抑制HAdV-3复制，减少HAdV-3诱导的细胞凋亡 。
- GN10506UmbelliferoneCAS: 93-35-6纯度: >99.00% / >98.50% / >99.50%
A derivative and metabolite of coumarin with diverse biological activities
- GN10540Fumalic acidCAS: 1135-24-6纯度: >99.00%
A phenol with diverse biological activities.Natural product, extracted from ligusticum chuanxiong.
- GN10578Polygalacic acidCAS: 22338-71-2纯度: >98.50%
A triterpenoid saponin with antioxidant and neuroprotective activities
- GN106295,7-dihydroxychromoneCAS: 31721-94-5纯度: >99.00%
5,7-dihydroxychromone是一种从花生壳中提取的黄酮类分解产物，能抑制曼陀罗、玉米、花生和小麦胚根的伸长。
- GN10659TheophyllineCAS: 58-55-9纯度: >98.00% / >99.50%
A phosphodiesterase inhibitor and adenosine receptor antagonist
- GN10669Glucosamine sulfateCAS: 29031-19-4纯度: >98.00%
氨基葡萄糖硫酸盐（D-氨基葡萄糖硫酸盐）是一种氨基糖，是糖基化蛋白质和脂质生化合成的重要前体，用作膳食补充剂。
- GN10676Palmitic acidCAS: 57-10-3纯度: >98.00% / >99.50%
棕榈酸 (PA) 是人体中最常见的饱和脂肪酸，可以从饮食中提供，也可以从其他脂肪酸、碳水化合物和氨基酸内源合成。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GN10470 | Eriodictyol | 552-58-9;4049-38-1 | >99.50% | |
圣草酚是一种从中药中分离出来的黄酮类化合物，具有抗氧化和抗炎活性。 | ||||
| GN10473 | Ginkgolide C | 15291-76-6 | >98.00% | |
A PAF receptor antagonist | ||||
| GN10489 | Hyodeoxycholic acid | 83-49-8 | >99.00% | |
A secondary bile acid | ||||
| GN10492 | Allantoin | 97-59-6 | >99.50% | |
A product of purine and uric acid metabolism | ||||
| GN10494 | Astragaloside IV | 84687-43-4 | >98.00% | |
Astragaloside IV是黄芪中提取的一种有效成分，可减轻心肌缺血/再灌注损伤，抑制HAdV-3复制，减少HAdV-3诱导的细胞凋亡 。 | ||||
| GN10506 | Umbelliferone | 93-35-6 | >99.00% / >98.50% / >99.50% | |
A derivative and metabolite of coumarin with diverse biological activities | ||||
| GN10518 | Chitosamine hydrochloride | 66-84-2 | >98.00% | |
An amino monosaccharide | ||||
| GN10540 | Fumalic acid | 1135-24-6 | >99.00% | |
A phenol with diverse biological activities.Natural product, extracted from ligusticum chuanxiong. | ||||
| GN10545 | Escin IA | 123748-68-5 | >98.00% | |
A triterpenoid saponin with diverse biological activities | ||||
| GN10552 | Syringic acid | 530-57-4 | >98.00% | |
A natural O-methylated phenolic acid | ||||
| GN10554 | Phytic acid | 83-86-3 | - | |
Phytic acid 是一种天然存在于豆科植物种子中的抗营养素。 | ||||
| GN10555 | Bilirubin | 635-65-4 | >98.50% / >99.00% | |
Bilirubin是血红素分解代谢产生的黄色终产物，可抑制ADAMTS13对F485-rVWF73-H、D633-rVWF73-H和GST-rVWF71-11K的切割活性，IC 50 值分别为13μM、70μM和17μM。 | ||||
| GN10558 | L-Carnitine inner salt (Standard) | 541-15-1 | >98.00% | |
A conditionally essential nutrient | ||||
| GN10564 | Ecdysterone | 5289-74-7 | >99.50% | |
Ecdysterone是一种天然存在的蜕皮激素，能够控制节肢动物的蜕皮（换羽）和变态。 | ||||
| GN10578 | Polygalacic acid | 22338-71-2 | >98.50% | |
A triterpenoid saponin with antioxidant and neuroprotective activities | ||||
| GN10622 | Shikimic acid | 138-59-0 | >99.50% | |
A cyclohexenecarboxylic acid | ||||
| GN10623 | Cholic acid | 81-25-4 | >98.00% | |
A primary bile acid | ||||
| GN10629 | 5,7-dihydroxychromone | 31721-94-5 | >99.00% | |
5,7-dihydroxychromone是一种从花生壳中提取的黄酮类分解产物，能抑制曼陀罗、玉米、花生和小麦胚根的伸长。 | ||||
| GN10659 | Theophylline | 58-55-9 | >98.00% / >99.50% | |
A phosphodiesterase inhibitor and adenosine receptor antagonist | ||||
| GN10668 | Coenzyme Q10 | 303-98-0 | >98.00% | |
A cofactor in the electron transport chain | ||||
| GN10669 | Glucosamine sulfate | 29031-19-4 | >98.00% | |
氨基葡萄糖硫酸盐（D-氨基葡萄糖硫酸盐）是一种氨基糖，是糖基化蛋白质和脂质生化合成的重要前体，用作膳食补充剂。 | ||||
| GN10676 | Palmitic acid | 57-10-3 | >98.00% / >99.50% | |
棕榈酸 (PA) 是人体中最常见的饱和脂肪酸，可以从饮食中提供，也可以从其他脂肪酸、碳水化合物和氨基酸内源合成。 | ||||
| GN10686 | Ginsenoside Rh2 | 78214-33-2 | >99.50% | |
A natural steroid glycoside with diverse effects | ||||
| GN10764 | Homovanillic acid | 306-08-1 | >95.00% | |
A dopamine metabolite | ||||