Proteases
Proteases(蛋白酶)
Proteases, also known as peptidases or proteolytic enzymes, consists of a large number of enzymes catalyzing the hydrolysis of peptide bonds and subsequently resulting in the degradation of protein substrates into amino acids. Proteases are involved in a wide range of human diseases, including cancer, neurodegenerative disorders, inflammatory diseases and cardiovascular diseases. Thus numerous proteases inhibitors (small molecules and proteins) have been identified to block activity of proteases. Proteases inhibitors can be classified into different types based on the class of proteases they inhibit through two general mechanisms, irreversible “trapping” reactions and reversible tight-binding reactions. Proteases inhibitors have been used as diagnostic or therapeutic agents for the treatment of proteases-related diseases.
- Aminopeptidase(21)
- ACE(75)
- Calpains(11)
- Carboxypeptidase(9)
- Cathepsin(65)
- DPP-4(18)
- Elastase(25)
- Gamma Secretase(50)
- HCV Protease(39)
- HSP(105)
- HIV Integrase(30)
- HIV Protease(35)
- MMP(195)
- NS3/4a protease(4)
- Serine Protease(19)
- Thrombin(47)
- Urokinase(2)
- Cysteine Protease
- Tyrosinases(50)
- Other Proteases(15)
- 15-PGDH(1)
- Acetyl-CoA Carboxylase(14)
- Acyltransferase(64)
- Aldehyde Dehydrogenase (ALDH)(30)
- Aminoacyl-tRNA Synthetase(9)
- ATGL(1)
- Dipeptidyl Peptidase(49)
- Drug Metabolite(513)
- E1/E2/E3 Enzyme(92)
- Endogenous Metabolite(1768)
- FABP(9)
- Farnesyl Transferase(20)
- Glutaminase(17)
- Glutathione Peroxidase(35)
- Isocitrate Dehydrogenase (IDH)(28)
- Lactate Dehydrogenase(19)
- Lipoxygenase(274)
- Mitochondrial Metabolism(260)
- NEDD8-activating Enzyme(6)
- Neprilysin(12)
- PAI-1(14)
- Ser/Thr Protease(49)
- Tryptophan Hydroxylase(12)
- Xanthine Oxidase(18)
- MALT1(10)
- Caspase(117)
- PCSK9(13)
- ADAMTS(1)
- Density Lipoprotein
- TrxR(1)
- DGK(3)
Proteases 相关产品(4079)
- GC48042Resolvin D2-d5CAS: 1881277-33-3纯度: >95.00%
An internal standard for the quantification of RvD2
- GC48060Rosuvastatin-d6 (sodium salt)CAS: 2070009-41-3纯度: >98.50%
An internal standard for the quantification of rosuvastatin
- GC48062RU-SKI 201 (hydrochloride)CAS: 2320262-09-5纯度: >95.00%
A neuropeptide with diverse biological activities
- GC48069Saxagliptin-13C-d2 (hydrochloride)CAS: 2699827-95-5纯度: >99.00%
A neuropeptide with diverse biological activities
- GC48083sn-Glycerol-3-phosphate (cyclohexyl ammonium salt hydrate)纯度: >95.00%
A neuropeptide with diverse biological activities
- GC48107Stearoyl-L-carnitine-d3 (chloride)CAS: 2245711-27-5纯度: >99.00%
An internal standard for the quantification of stearoyl-L-carnitine
- GC48124Tamoxifen-d5CAS: 157698-32-3纯度: >99.00%
An internal standard for the quantification of tamoxifen
- GC48174Thiorphan-d5CAS: 2183240-70-0纯度: >99.00%
An internal standard for the quantification of thiorphan
- GC48200Trelagliptin-13C-d3CAS: 2707203-34-5纯度: >99.00%
A neuropeptide with diverse biological activities
- GC48250Vildagliptin-d7CAS: 1133208-42-0纯度: >99.00%
An internal standard for the quantification of vildagliptin
- GC48267Zileuton-d4CAS: 1189878-76-9纯度: >99.00%
An internal standard for the quantification of zileuton
- GC48416Chlorhexidine-d8 (hydrochloride)CAS: 2012598-75-1纯度: >99.00%
An internal standard for the quantification of chlorhexidine
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC48042 | Resolvin D2-d5 | 1881277-33-3 | >95.00% | |
An internal standard for the quantification of RvD2 | ||||
| GC48043 | Resolvin D3-d5 | 916888-47-6 | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC48044 | Resolvin E1-d4 | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC48045 | Resolvin E4 | 1781227-87-9 | >95.00% | |
A specialized pro-resolving mediator | ||||
| GC48060 | Rosuvastatin-d6 (sodium salt) | 2070009-41-3 | >98.50% | |
An internal standard for the quantification of rosuvastatin | ||||
| GC48062 | RU-SKI 201 (hydrochloride) | 2320262-09-5 | >95.00% | |
A neuropeptide with diverse biological activities | ||||
| GC48069 | Saxagliptin-13C-d2 (hydrochloride) | 2699827-95-5 | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC48077 | SHS4121705 | 2379550-82-8 | >98.00% | |
A mitochondrial uncoupler | ||||
| GC48083 | sn-Glycerol-3-phosphate (cyclohexyl ammonium salt hydrate) | - | >95.00% | |
A neuropeptide with diverse biological activities | ||||
| GC48086 | Solanesol | 13190-97-1 | >90.00% / >95.00% | |
A trisesquiterpenoid with diverse biological activities | ||||
| GC48093 | Spiromesifen | 283594-90-1 | >95.00% | |
An insecticide and acaricide | ||||
| GC48101 | SSAA09E1 | 433212-75-0 | >98.00% | |
A SARS-CoV entry inhibitor | ||||
| GC48107 | Stearoyl-L-carnitine-d3 (chloride) | 2245711-27-5 | >99.00% | |
An internal standard for the quantification of stearoyl-L-carnitine | ||||
| GC48124 | Tamoxifen-d5 | 157698-32-3 | >99.00% | |
An internal standard for the quantification of tamoxifen | ||||
| GC48136 | Telaprevir-d4 | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC48174 | Thiorphan-d5 | 2183240-70-0 | >99.00% | |
An internal standard for the quantification of thiorphan | ||||
| GC48192 | trans-2-Octenoyl-L-carnitine | 152064-94-3 | >95.00% | |
A synthetic carnitine | ||||
| GC48200 | Trelagliptin-13C-d3 | 2707203-34-5 | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC48250 | Vildagliptin-d7 | 1133208-42-0 | >99.00% | |
An internal standard for the quantification of vildagliptin | ||||
| GC48267 | Zileuton-d4 | 1189878-76-9 | >99.00% | |
An internal standard for the quantification of zileuton | ||||
| GC48398 | WST-1 | 150849-52-8 | >98.00% | |
A water-soluble and cell-permeable tetrazolium dye | ||||
| GC48416 | Chlorhexidine-d8 (hydrochloride) | 2012598-75-1 | >99.00% | |
An internal standard for the quantification of chlorhexidine | ||||
| GC48421 | GW 280264X | 866924-39-2 | >98.00% | |
An ADAM17/TACE and ADAM10 inhibitor | ||||
| GC48425 | C18 D-threo Ceramide (d18:1/18:0) | 252039-53-5 | >98.00% | |
A synthetic ceramide | ||||