Proteases
Proteases(蛋白酶)
Proteases, also known as peptidases or proteolytic enzymes, consists of a large number of enzymes catalyzing the hydrolysis of peptide bonds and subsequently resulting in the degradation of protein substrates into amino acids. Proteases are involved in a wide range of human diseases, including cancer, neurodegenerative disorders, inflammatory diseases and cardiovascular diseases. Thus numerous proteases inhibitors (small molecules and proteins) have been identified to block activity of proteases. Proteases inhibitors can be classified into different types based on the class of proteases they inhibit through two general mechanisms, irreversible “trapping” reactions and reversible tight-binding reactions. Proteases inhibitors have been used as diagnostic or therapeutic agents for the treatment of proteases-related diseases.
- Aminopeptidase(21)
- ACE(75)
- Calpains(11)
- Carboxypeptidase(9)
- Cathepsin(65)
- DPP-4(18)
- Elastase(25)
- Gamma Secretase(50)
- HCV Protease(39)
- HSP(105)
- HIV Integrase(30)
- HIV Protease(35)
- MMP(195)
- NS3/4a protease(4)
- Serine Protease(19)
- Thrombin(47)
- Urokinase(2)
- Cysteine Protease
- Tyrosinases(50)
- Other Proteases(15)
- 15-PGDH(1)
- Acetyl-CoA Carboxylase(14)
- Acyltransferase(64)
- Aldehyde Dehydrogenase (ALDH)(30)
- Aminoacyl-tRNA Synthetase(9)
- ATGL(1)
- Dipeptidyl Peptidase(49)
- Drug Metabolite(513)
- E1/E2/E3 Enzyme(92)
- Endogenous Metabolite(1768)
- FABP(9)
- Farnesyl Transferase(20)
- Glutaminase(17)
- Glutathione Peroxidase(35)
- Isocitrate Dehydrogenase (IDH)(28)
- Lactate Dehydrogenase(19)
- Lipoxygenase(274)
- Mitochondrial Metabolism(260)
- NEDD8-activating Enzyme(6)
- Neprilysin(12)
- PAI-1(14)
- Ser/Thr Protease(49)
- Tryptophan Hydroxylase(12)
- Xanthine Oxidase(18)
- MALT1(10)
- Caspase(117)
- PCSK9(13)
- ADAMTS(1)
- Density Lipoprotein
- TrxR(1)
- DGK(3)
Proteases 相关产品(4079)
- GC47712Mycophenolate Mofetil-d4CAS: 1132748-21-0纯度: >99.00%
An internal standard for the quantification of mycophenolate mofetil
- GC47714Myristoyl-L-carnitine-14,14,14-d3 (chloride)纯度: >99.00%
A neuropeptide with diverse biological activities
- GC47715Myristoyl-L-carnitine-d3 (chloride)CAS: 1334532-25-0纯度: >99.50%
An internal standard for the quantification of myristoyl-L-carnitine
- GC47716Myxochelin ACAS: 120243-02-9纯度: >98.00%
A microbial metabolite with diverse biological activities
- GC47735N-acetyl Desethylchloroquine-d4CAS: 1216619-20-3纯度: >99.00%
An internal standard for the quantification of N-acetyl desethylchloroquine
- GC47747Napyradiomycin A1CAS: 103106-24-7纯度: >70.00%
A fungal metabolite with diverse biological activities
- GC47751Nateglinide-d5CAS: 1227666-13-8纯度: >99.00%
An internal standard for the quantification of nateglinide
- GC47756N-desmethyl Rosuvastatin (sodium salt hydrate)纯度: >95.00%
An active metabolite of rosuvastatin
- GC47757N-Desmethylclozapine-d8CAS: 1189888-77-4纯度: >99.00%
An internal standard for the quantification of N-desmethylclozapine
- GC47816Octanoyl-L-carnitine-d3 (chloride)CAS: 1334532-24-9纯度: >99.50%
An internal standard for the quantification of octanoyl-L-carnitine
- GC47826Omeprazole sulfone-d3CAS: 2749628-17-7纯度: >99.00%
An internal standard for the quantification of omeprazole sulfone
- GC47868Palmitoyl-L-carnitine-d3 (chloride)CAS: 1334532-26-1纯度: >99.50% / >98.00%
Palmitoyl-L-carnitine-d3 (chloride)是Palmitoyl-L-carnitine的氘化形式，主要在质谱脂质分析中用作内标。
- GC47923Paraxanthine-d6CAS: 117490-41-2纯度: >99.00%
An internal standard for the quantification of paraxanthine
- GC47965Pomalidomide-d5CAS: 1377838-49-7纯度: >99.00%
An internal standard for the quantification of pomalidomide
- GC47980Propionyl-L-carnitine-d3 (chloride)CAS: 1334532-19-2纯度: >99.00%
An internal standard for the quantification of propionyl-L-carnitine
- GC48041Resolvin D1-d5CAS: 1881277-32-2纯度: >99.00%
An internal standard for the quantification of RvD1
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC47708 | MPro Inhibitor 11b | 2413716-71-7 | >98.00% | |
An inhibitor of SARS-CoV-2 M pro | ||||
| GC47712 | Mycophenolate Mofetil-d4 | 1132748-21-0 | >99.00% | |
An internal standard for the quantification of mycophenolate mofetil | ||||
| GC47714 | Myristoyl-L-carnitine-14,14,14-d3 (chloride) | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC47715 | Myristoyl-L-carnitine-d3 (chloride) | 1334532-25-0 | >99.50% | |
An internal standard for the quantification of myristoyl-L-carnitine | ||||
| GC47716 | Myxochelin A | 120243-02-9 | >98.00% | |
A microbial metabolite with diverse biological activities | ||||
| GC47735 | N-acetyl Desethylchloroquine-d4 | 1216619-20-3 | >99.00% | |
An internal standard for the quantification of N-acetyl desethylchloroquine | ||||
| GC47739 | NADH (sodium salt hydrate) | 1949720-50-6 | >95.00% / >98.00% | |
A reduced form of NAD + | ||||
| GC47740 | NADP+ (hydrate) | - | >90.00% | |
A neuropeptide with diverse biological activities | ||||
| GC47746 | NAP 226-90 | 139306-10-8 | >98.00% | |
A metabolite of rivastigmine | ||||
| GC47747 | Napyradiomycin A1 | 103106-24-7 | >70.00% | |
A fungal metabolite with diverse biological activities | ||||
| GC47751 | Nateglinide-d5 | 1227666-13-8 | >99.00% | |
An internal standard for the quantification of nateglinide | ||||
| GC47756 | N-desmethyl Rosuvastatin (sodium salt hydrate) | - | >95.00% | |
An active metabolite of rosuvastatin | ||||
| GC47757 | N-Desmethylclozapine-d8 | 1189888-77-4 | >99.00% | |
An internal standard for the quantification of N-desmethylclozapine | ||||
| GC47789 | N-Oleoyl Glutamine | 247150-73-8 | >99.50% | |
An endogenous N-acyl amine | ||||
| GC47816 | Octanoyl-L-carnitine-d3 (chloride) | 1334532-24-9 | >99.50% | |
An internal standard for the quantification of octanoyl-L-carnitine | ||||
| GC47826 | Omeprazole sulfone-d3 | 2749628-17-7 | >99.00% | |
An internal standard for the quantification of omeprazole sulfone | ||||
| GC47847 | Oxamyl | 23135-22-0 | >98.00% | |
A carbamate pesticide | ||||
| GC47868 | Palmitoyl-L-carnitine-d3 (chloride) | 1334532-26-1 | >99.50% / >98.00% | |
Palmitoyl-L-carnitine-d3 (chloride)是Palmitoyl-L-carnitine的氘化形式，主要在质谱脂质分析中用作内标。 | ||||
| GC47923 | Paraxanthine-d6 | 117490-41-2 | >99.00% | |
An internal standard for the quantification of paraxanthine | ||||
| GC47965 | Pomalidomide-d5 | 1377838-49-7 | >99.00% | |
An internal standard for the quantification of pomalidomide | ||||
| GC47980 | Propionyl-L-carnitine-d3 (chloride) | 1334532-19-2 | >99.00% | |
An internal standard for the quantification of propionyl-L-carnitine | ||||
| GC48030 | RC574 | 2584411-87-8 | >98.00% | |
An inhibitor of ferroptosis | ||||
| GC48035 | RCTR1 | 2095607-49-9 | >98.00% | |
A specialized pro-resolving mediator | ||||
| GC48041 | Resolvin D1-d5 | 1881277-32-2 | >99.00% | |
An internal standard for the quantification of RvD1 | ||||