Proteases
Proteases(蛋白酶)
Proteases, also known as peptidases or proteolytic enzymes, consists of a large number of enzymes catalyzing the hydrolysis of peptide bonds and subsequently resulting in the degradation of protein substrates into amino acids. Proteases are involved in a wide range of human diseases, including cancer, neurodegenerative disorders, inflammatory diseases and cardiovascular diseases. Thus numerous proteases inhibitors (small molecules and proteins) have been identified to block activity of proteases. Proteases inhibitors can be classified into different types based on the class of proteases they inhibit through two general mechanisms, irreversible “trapping” reactions and reversible tight-binding reactions. Proteases inhibitors have been used as diagnostic or therapeutic agents for the treatment of proteases-related diseases.
- Aminopeptidase(21)
- ACE(75)
- Calpains(11)
- Carboxypeptidase(9)
- Cathepsin(65)
- DPP-4(18)
- Elastase(25)
- Gamma Secretase(50)
- HCV Protease(39)
- HSP(105)
- HIV Integrase(30)
- HIV Protease(35)
- MMP(195)
- NS3/4a protease(4)
- Serine Protease(19)
- Thrombin(47)
- Urokinase(2)
- Cysteine Protease
- Tyrosinases(50)
- Other Proteases(15)
- 15-PGDH(1)
- Acetyl-CoA Carboxylase(14)
- Acyltransferase(64)
- Aldehyde Dehydrogenase (ALDH)(30)
- Aminoacyl-tRNA Synthetase(9)
- ATGL(1)
- Dipeptidyl Peptidase(49)
- Drug Metabolite(513)
- E1/E2/E3 Enzyme(92)
- Endogenous Metabolite(1768)
- FABP(9)
- Farnesyl Transferase(20)
- Glutaminase(17)
- Glutathione Peroxidase(35)
- Isocitrate Dehydrogenase (IDH)(28)
- Lactate Dehydrogenase(19)
- Lipoxygenase(274)
- Mitochondrial Metabolism(260)
- NEDD8-activating Enzyme(6)
- Neprilysin(12)
- PAI-1(14)
- Ser/Thr Protease(49)
- Tryptophan Hydroxylase(12)
- Xanthine Oxidase(18)
- MALT1(10)
- Caspase(117)
- PCSK9(13)
- ADAMTS(1)
- Density Lipoprotein
- TrxR(1)
- DGK(3)
Proteases 相关产品(4079)
- GC47546Lauroyl-L-carnitine-12,12,12-d3 (chloride)纯度: >99.00%
A neuropeptide with diverse biological activities
- GC47547Lauroyl-L-carnitine-d3 (chloride)CAS: 2687960-76-3纯度: >99.00%
A neuropeptide with diverse biological activities
- GC47548L-Carnitine-d3 (chloride)CAS: 350818-62-1纯度: >98.00%
An internal standard for the quantification of L-carnitine
- GC47558Leukotriene C4-d5 methyl esterCAS: 73958-10-8纯度: >99.00%
A neuropeptide with diverse biological activities
- GC47573Lopinavir-d8CAS: 1322625-54-6纯度: >99.00%
An internal standard for the quantification of lopinavir
- GC47575Loratadine-d5CAS: 1020719-57-6纯度: >99.00%
An internal standard for the quantification of loratadine
- GC47647Methiocarb-d3CAS: 1581694-94-1纯度: >99.00%
An internal standard for the quantification of methiocarb
- GC47650Methotrexate-d3CAS: 432545-63-6纯度: >99.00%
An internal standard for the quantification of methotrexate
- GC47663Methylene Blue (hydrate)CAS: 122965-43-9纯度: >96.00%
A cationic dye with diverse biological activities
- GC47701Montelukast-d6 (sodium salt)CAS: 2673270-26-1纯度: >99.00%
A neuropeptide with diverse biological activities
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC47531 | Kresoxim-methyl | 143390-89-0 | >95.00% | |
A fungicide | ||||
| GC47546 | Lauroyl-L-carnitine-12,12,12-d3 (chloride) | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC47547 | Lauroyl-L-carnitine-d3 (chloride) | 2687960-76-3 | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC47548 | L-Carnitine-d3 (chloride) | 350818-62-1 | >98.00% | |
An internal standard for the quantification of L-carnitine | ||||
| GC47555 | Leukotriene A4-d5 methyl ester | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC47558 | Leukotriene C4-d5 methyl ester | 73958-10-8 | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC47570 | Lipoxygenin | 2247911-68-6 | >98.00% | |
An inhibitor of 5-LO | ||||
| GC47573 | Lopinavir-d8 | 1322625-54-6 | >99.00% | |
An internal standard for the quantification of lopinavir | ||||
| GC47574 | Loratadine-d4 | 2748435-73-4 | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC47575 | Loratadine-d5 | 1020719-57-6 | >99.00% | |
An internal standard for the quantification of loratadine | ||||
| GC47598 | Maresin 1-d5 | 1268720-28-0 | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC47599 | Maresin 2-d5 | 1639809-46-3 | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC47620 | Mensacarcin | 808750-39-2 | >98.00% | |
A bacterial metabolite with anticancer activity | ||||
| GC47646 | Methiocarb | 2032-65-7 | >98.00% | |
A carbamate pesticide | ||||
| GC47647 | Methiocarb-d3 | 1581694-94-1 | >99.00% | |
An internal standard for the quantification of methiocarb | ||||
| GC47648 | Methomyl | 16752-77-5 | >98.00% | |
A carbamate insecticide | ||||
| GC47650 | Methotrexate-d3 | 432545-63-6 | >99.00% | |
An internal standard for the quantification of methotrexate | ||||
| GC47660 | Methyl Parathion | 298-00-0 | >98.00% | |
An organophosphate insecticide | ||||
| GC47663 | Methylene Blue (hydrate) | 122965-43-9 | >96.00% | |
A cationic dye with diverse biological activities | ||||
| GC47683 | MitoB-d15 | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC47684 | MitoP-d15 | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC47685 | MIT-PZR | 2376848-06-3 | >98.00% | |
A mitochondria-targeted fluorescent probe | ||||
| GC47701 | Montelukast-d6 (sodium salt) | 2673270-26-1 | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC47707 | MPro Inhibitor 11a | 2103278-86-8 | >95.00% | |
An inhibitor of SARS-CoV-2 M pro | ||||