Proteases
Proteases(蛋白酶)
Proteases, also known as peptidases or proteolytic enzymes, consists of a large number of enzymes catalyzing the hydrolysis of peptide bonds and subsequently resulting in the degradation of protein substrates into amino acids. Proteases are involved in a wide range of human diseases, including cancer, neurodegenerative disorders, inflammatory diseases and cardiovascular diseases. Thus numerous proteases inhibitors (small molecules and proteins) have been identified to block activity of proteases. Proteases inhibitors can be classified into different types based on the class of proteases they inhibit through two general mechanisms, irreversible “trapping” reactions and reversible tight-binding reactions. Proteases inhibitors have been used as diagnostic or therapeutic agents for the treatment of proteases-related diseases.
- Aminopeptidase(21)
- ACE(75)
- Calpains(11)
- Carboxypeptidase(9)
- Cathepsin(65)
- DPP-4(18)
- Elastase(25)
- Gamma Secretase(50)
- HCV Protease(39)
- HSP(105)
- HIV Integrase(30)
- HIV Protease(35)
- MMP(195)
- NS3/4a protease(4)
- Serine Protease(19)
- Thrombin(47)
- Urokinase(2)
- Cysteine Protease
- Tyrosinases(50)
- Other Proteases(15)
- 15-PGDH(1)
- Acetyl-CoA Carboxylase(14)
- Acyltransferase(64)
- Aldehyde Dehydrogenase (ALDH)(30)
- Aminoacyl-tRNA Synthetase(9)
- ATGL(1)
- Dipeptidyl Peptidase(49)
- Drug Metabolite(513)
- E1/E2/E3 Enzyme(92)
- Endogenous Metabolite(1768)
- FABP(9)
- Farnesyl Transferase(20)
- Glutaminase(17)
- Glutathione Peroxidase(35)
- Isocitrate Dehydrogenase (IDH)(28)
- Lactate Dehydrogenase(19)
- Lipoxygenase(274)
- Mitochondrial Metabolism(260)
- NEDD8-activating Enzyme(6)
- Neprilysin(12)
- PAI-1(14)
- Ser/Thr Protease(49)
- Tryptophan Hydroxylase(12)
- Xanthine Oxidase(18)
- MALT1(10)
- Caspase(117)
- PCSK9(13)
- ADAMTS(1)
- Density Lipoprotein
- TrxR(1)
- DGK(3)
Proteases 相关产品(4079)
- GC47178Decanoyl-L-carnitine-d3 (chloride)CAS: 2483831-87-2纯度: >99.50%
A neuropeptide with diverse biological activities
- GC47193Desethyl Hydroxychloroquine-d4CAS: 1854126-47-8纯度: >99.00%
An internal standard for the quantification of desethyl hydroxychloroquine
- GC47195Desethylchloroquine-d4CAS: 1189971-72-9纯度: >99.00%
An internal standard for the quantification of desethylchloroquine
- GC47196Desloratadine-d4CAS: 2713301-38-1纯度: >99.00%
An internal standard for the quantification of desloratadine
- GC47243DL-Carnitine-d9 (chloride)CAS: 1219386-75-0纯度: >99.00%
An internal standard for the quantification of carnitine
- GC47320Ethynyl Estradiol 3-β-D-Glucuronide (hydrate)纯度: >96.00%
A metabolite of ethynyl estradiol
- GC47323Etofenamate-d4CAS: 1329837-73-1纯度: >99.00%
An internal standard for the quantification of etofenamate
- GC47351Fingolimod-d4CAS: 1346747-38-3纯度: >97.50%
An internal standard for the quantification of fingolimod
- GC47366Flurbiprofen-d3CAS: 1185133-81-6纯度: >99.00%
An internal standard for the quantification of flurbiprofen
- GC47431Hexanoyl-L-carnitine-d3 (chloride)CAS: 2483831-95-2纯度: >99.00%
A neuropeptide with diverse biological activities
- GC47455Indinavir-d6CAS: 185897-02-3纯度: >99.00%
An internal standard for the quantification of indinavir
- GC47470Isovaleryl-L-carnitine-d3 (chloride)纯度: >99.00%
A neuropeptide with diverse biological activities
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC47177 | Decanoyl-L-carnitine (hydrate) | - | >95.00% | |
A neuropeptide with diverse biological activities | ||||
| GC47178 | Decanoyl-L-carnitine-d3 (chloride) | 2483831-87-2 | >99.50% | |
A neuropeptide with diverse biological activities | ||||
| GC47193 | Desethyl Hydroxychloroquine-d4 | 1854126-47-8 | >99.00% | |
An internal standard for the quantification of desethyl hydroxychloroquine | ||||
| GC47195 | Desethylchloroquine-d4 | 1189971-72-9 | >99.00% | |
An internal standard for the quantification of desethylchloroquine | ||||
| GC47196 | Desloratadine-d4 | 2713301-38-1 | >99.00% | |
An internal standard for the quantification of desloratadine | ||||
| GC47238 | Diquat (bromide) | 85-00-7 | >98.00% | |
An herbicide | ||||
| GC47239 | Diquat-d12 (bromide) | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC47240 | Diquat-d4 (bromide) | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC47243 | DL-Carnitine-d9 (chloride) | 1219386-75-0 | >99.00% | |
An internal standard for the quantification of carnitine | ||||
| GC47274 | DS44960156 | 2361327-08-2 | >98.00% | |
An MTHFD2 inhibitor | ||||
| GC47312 | Etherolenic Acid | 2247927-22-4 | >95.00% | |
A divinyl ether oxylipin | ||||
| GC47320 | Ethynyl Estradiol 3-β-D-Glucuronide (hydrate) | - | >96.00% | |
A metabolite of ethynyl estradiol | ||||
| GC47323 | Etofenamate-d4 | 1329837-73-1 | >99.00% | |
An internal standard for the quantification of etofenamate | ||||
| GC47326 | Etoxazole | 153233-91-1 | >98.00% | |
An organofluorine acaricide | ||||
| GC47330 | Faldaprevir-d6 | 2750534-88-2 | >99.00% | |
Faldaprevir-d6 是氘标记的 Faldaprevir。 | ||||
| GC47339 | Fenpropimorph | 67564-91-4 | >98.00% | |
A fungicide that inhibits the sterol pathway | ||||
| GC47351 | Fingolimod-d4 | 1346747-38-3 | >97.50% | |
An internal standard for the quantification of fingolimod | ||||
| GC47366 | Flurbiprofen-d3 | 1185133-81-6 | >99.00% | |
An internal standard for the quantification of flurbiprofen | ||||
| GC47370 | Fosinopril (sodium salt) | 88889-14-9 | >99.00% | |
A prodrug form of fosinoprilat | ||||
| GC47399 | Geranylgeranoic Acid | 83807-40-3 | >95.00% | |
An isoprenoid with anticancer activity | ||||
| GC47430 | Hexanoyl-L-carnitine (chloride) | 162067-53-0 | >95.00% | |
A medium-chain acylcarnitine | ||||
| GC47431 | Hexanoyl-L-carnitine-d3 (chloride) | 2483831-95-2 | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC47455 | Indinavir-d6 | 185897-02-3 | >99.00% | |
An internal standard for the quantification of indinavir | ||||
| GC47470 | Isovaleryl-L-carnitine-d3 (chloride) | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||