Proteases
Proteases(蛋白酶)
Proteases, also known as peptidases or proteolytic enzymes, consists of a large number of enzymes catalyzing the hydrolysis of peptide bonds and subsequently resulting in the degradation of protein substrates into amino acids. Proteases are involved in a wide range of human diseases, including cancer, neurodegenerative disorders, inflammatory diseases and cardiovascular diseases. Thus numerous proteases inhibitors (small molecules and proteins) have been identified to block activity of proteases. Proteases inhibitors can be classified into different types based on the class of proteases they inhibit through two general mechanisms, irreversible “trapping” reactions and reversible tight-binding reactions. Proteases inhibitors have been used as diagnostic or therapeutic agents for the treatment of proteases-related diseases.
- Aminopeptidase(21)
- ACE(75)
- Calpains(11)
- Carboxypeptidase(9)
- Cathepsin(65)
- DPP-4(18)
- Elastase(25)
- Gamma Secretase(50)
- HCV Protease(39)
- HSP(105)
- HIV Integrase(30)
- HIV Protease(35)
- MMP(195)
- NS3/4a protease(4)
- Serine Protease(19)
- Thrombin(47)
- Urokinase(2)
- Cysteine Protease
- Tyrosinases(50)
- Other Proteases(15)
- 15-PGDH(1)
- Acetyl-CoA Carboxylase(14)
- Acyltransferase(64)
- Aldehyde Dehydrogenase (ALDH)(30)
- Aminoacyl-tRNA Synthetase(9)
- ATGL(1)
- Dipeptidyl Peptidase(49)
- Drug Metabolite(513)
- E1/E2/E3 Enzyme(92)
- Endogenous Metabolite(1768)
- FABP(9)
- Farnesyl Transferase(20)
- Glutaminase(17)
- Glutathione Peroxidase(35)
- Isocitrate Dehydrogenase (IDH)(28)
- Lactate Dehydrogenase(19)
- Lipoxygenase(274)
- Mitochondrial Metabolism(260)
- NEDD8-activating Enzyme(6)
- Neprilysin(12)
- PAI-1(14)
- Ser/Thr Protease(49)
- Tryptophan Hydroxylase(12)
- Xanthine Oxidase(18)
- MALT1(10)
- Caspase(117)
- PCSK9(13)
- ADAMTS(1)
- Density Lipoprotein
- TrxR(1)
- DGK(3)
Proteases 相关产品(4079)
- GC46854Anastrozole-d12CAS: 120512-32-5纯度: >99.00%
An internal standard for the quantification of anastrozole
- GC46887Atazanavir-d6CAS: 1092540-50-5纯度: >99.00%
An internal standard for the quantification of atazanavir
- GC46890Atorvastatin-d5 (calcium salt)CAS: 222412-82-0纯度: >99.00%
An internal standard for the quantification of atorvastatin
- GC46936Boceprevir-d9CAS: 1256751-11-7纯度: >99.00%
An internal standard for the quantification of boceprevir
- GC46972Butyryl-L-carnitine-d3 (chloride)CAS: 1334532-21-6纯度: >99.00%
An internal standard for the quantification of butyryl-L-carnitine
- GC47022Camostat-d6 (hydrochloride)CAS: 2930627-60-2纯度: >99.00%
A neuropeptide with diverse biological activities
- GC47040Carebastine-d5CAS: 1189661-02-6纯度: >99.00%
An internal standard for the quantification of carebastine
- GC47042Carfilzomib-d8CAS: 1537187-53-3纯度: >99.00%
An internal standard for the quantification of carfilzomib
- GC47087Cilastatin-15N-d3CAS: 2738376-83-3纯度: >99.00%
A neuropeptide with diverse biological activities
- GC47114Coenzyme A (lithium salt hydrate)纯度: >95.00%
An essential cofactor in enzymatic acetyl transfer reactions
- GC47116Coenzyme Q10-d6CAS: 110971-02-3纯度: >99.00%
An internal standard for the quantification of CoQ 10
- GC47117Colchicine-d6CAS: 1217651-73-4纯度: >99.00%
An internal standard for the quantification of colchicine
- GC47123Coumarin-Quinone ConjugateCAS: 2741190-31-6纯度: >95.00%
A fluorescent substrate for NADH:ubiquinone oxidoreductases
- GC47160Cystamine-d8 (hydrochloride)CAS: 2712126-51-5纯度: >99.00%
A neuropeptide with diverse biological activities
- GC47173Darunavir-d9CAS: 1133378-37-6纯度: >99.00%
An internal standard for the quantification of darunavir
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC46841 | Amiloride (hydrochloride) (hydrate) | - | >98.00% | |
具有多种生物活性的神经肽 | ||||
| GC46854 | Anastrozole-d12 | 120512-32-5 | >99.00% | |
An internal standard for the quantification of anastrozole | ||||
| GC46883 | AS-2077715 | 1637356-98-9 | >70.00% | |
An inhibitor of fungal complex III | ||||
| GC46885 | Asperglaucide | 56121-42-7 | >98.00% | |
An amide with diverse biological activities | ||||
| GC46887 | Atazanavir-d6 | 1092540-50-5 | >99.00% | |
An internal standard for the quantification of atazanavir | ||||
| GC46890 | Atorvastatin-d5 (calcium salt) | 222412-82-0 | >99.00% | |
An internal standard for the quantification of atorvastatin | ||||
| GC46893 | Atranorin | 479-20-9 | >99.00% | |
A depside lichen metabolite with diverse biological activities | ||||
| GC46936 | Boceprevir-d9 | 1256751-11-7 | >99.00% | |
An internal standard for the quantification of boceprevir | ||||
| GC46943 | Boscalid | 188425-85-6 | >95.00% | |
A broad-spectrum carboxamide fungicide | ||||
| GC46955 | Bromoenol lactone-d7 | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC46972 | Butyryl-L-carnitine-d3 (chloride) | 1334532-21-6 | >99.00% | |
An internal standard for the quantification of butyryl-L-carnitine | ||||
| GC47022 | Camostat-d6 (hydrochloride) | 2930627-60-2 | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC47040 | Carebastine-d5 | 1189661-02-6 | >99.00% | |
An internal standard for the quantification of carebastine | ||||
| GC47042 | Carfilzomib-d8 | 1537187-53-3 | >99.00% | |
An internal standard for the quantification of carfilzomib | ||||
| GC47065 | CAY10773 | 1648546-79-5 | >98.00% | |
A derivative of sorafenib | ||||
| GC47087 | Cilastatin-15N-d3 | 2738376-83-3 | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC47096 | Citrinin-13C13 | - | >98.00% | |
A neuropeptide with diverse biological activities | ||||
| GC47114 | Coenzyme A (lithium salt hydrate) | - | >95.00% | |
An essential cofactor in enzymatic acetyl transfer reactions | ||||
| GC47116 | Coenzyme Q10-d6 | 110971-02-3 | >99.00% | |
An internal standard for the quantification of CoQ 10 | ||||
| GC47117 | Colchicine-d6 | 1217651-73-4 | >99.00% | |
An internal standard for the quantification of colchicine | ||||
| GC47123 | Coumarin-Quinone Conjugate | 2741190-31-6 | >95.00% | |
A fluorescent substrate for NADH:ubiquinone oxidoreductases | ||||
| GC47160 | Cystamine-d8 (hydrochloride) | 2712126-51-5 | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC47173 | Darunavir-d9 | 1133378-37-6 | >99.00% | |
An internal standard for the quantification of darunavir | ||||
| GC47176 | Decanoyl-Coenzyme A (hydrate) | - | >90.00% | |
A neuropeptide with diverse biological activities | ||||