Proteases
Proteases(蛋白酶)
Proteases, also known as peptidases or proteolytic enzymes, consists of a large number of enzymes catalyzing the hydrolysis of peptide bonds and subsequently resulting in the degradation of protein substrates into amino acids. Proteases are involved in a wide range of human diseases, including cancer, neurodegenerative disorders, inflammatory diseases and cardiovascular diseases. Thus numerous proteases inhibitors (small molecules and proteins) have been identified to block activity of proteases. Proteases inhibitors can be classified into different types based on the class of proteases they inhibit through two general mechanisms, irreversible “trapping” reactions and reversible tight-binding reactions. Proteases inhibitors have been used as diagnostic or therapeutic agents for the treatment of proteases-related diseases.
- Aminopeptidase(21)
- ACE(75)
- Calpains(11)
- Carboxypeptidase(9)
- Cathepsin(65)
- DPP-4(18)
- Elastase(25)
- Gamma Secretase(50)
- HCV Protease(39)
- HSP(105)
- HIV Integrase(30)
- HIV Protease(35)
- MMP(195)
- NS3/4a protease(4)
- Serine Protease(19)
- Thrombin(47)
- Urokinase(2)
- Cysteine Protease
- Tyrosinases(50)
- Other Proteases(15)
- 15-PGDH(1)
- Acetyl-CoA Carboxylase(14)
- Acyltransferase(64)
- Aldehyde Dehydrogenase (ALDH)(30)
- Aminoacyl-tRNA Synthetase(9)
- ATGL(1)
- Dipeptidyl Peptidase(49)
- Drug Metabolite(513)
- E1/E2/E3 Enzyme(92)
- Endogenous Metabolite(1768)
- FABP(9)
- Farnesyl Transferase(20)
- Glutaminase(17)
- Glutathione Peroxidase(35)
- Isocitrate Dehydrogenase (IDH)(28)
- Lactate Dehydrogenase(19)
- Lipoxygenase(274)
- Mitochondrial Metabolism(260)
- NEDD8-activating Enzyme(6)
- Neprilysin(12)
- PAI-1(14)
- Ser/Thr Protease(49)
- Tryptophan Hydroxylase(12)
- Xanthine Oxidase(18)
- MALT1(10)
- Caspase(117)
- PCSK9(13)
- ADAMTS(1)
- Density Lipoprotein
- TrxR(1)
- DGK(3)
Proteases 相关产品(4079)
- GC4642013(S)-HODE-d4CAS: 139408-39-2纯度: >99.00%
An internal standard for the quantification of 13-HODE
- GC4644215(S)-HETE-d8CAS: 84807-87-4纯度: >99.00%
An internal standard for the quantification of 15(S)-HETE
- GC465993-hydroxy-3-methylglutaryl-Coenzyme A-d3 (ammonium salt)纯度: >99.00%
A neuropeptide with diverse biological activities
- GC467327(S),17(S)-dihydroxy-8(E),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic AcidCAS: 887752-13-8纯度: >98.00%
A metabolite of DPA with anti-inflammatory properties
- GC46789Acetyl-L-carnitine-d3 (chloride)CAS: 362049-62-5纯度: >98.50%
An internal standard for the quantification of L-acetylcarnitine
- GC46798Adapalene-d3CAS: 1276433-89-6纯度: >99.00%
An internal standard for the quantification of adapalene
- GC46812Aflatoxin G1-13C17CAS: 1217444-07-9纯度: >98.00%
An internal standard for the quantification of aflatoxin G 1
- GC46814Aflatoxin M1-13C17CAS: 2707441-97-0纯度: >98.00%
A neuropeptide with diverse biological activities
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC46420 | 13(S)-HODE-d4 | 139408-39-2 | >99.00% | |
An internal standard for the quantification of 13-HODE | ||||
| GC46436 | 13-OxoODE-d3 | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC46441 | 15(S)-HEPE-d5 | 2750534-74-6 | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC46442 | 15(S)-HETE-d8 | 84807-87-4 | >99.00% | |
An internal standard for the quantification of 15(S)-HETE | ||||
| GC46451 | 16F16 | 922507-80-0 | >98.00% | |
A PDI inhibitor | ||||
| GC46457 | 17(R)-Resolvin D1-d5 | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC46471 | 17β-hydroxy Exemestane-d3 | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC46482 | 1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC | 22252-07-9 | >95.00% | |
A lysophospholipid | ||||
| GC46488 | 1-Palmitoyl-2-Docosahexaenoyl-sn-glycero-3-PC | 59403-54-2 | >95.00% | |
A phospholipid | ||||
| GC46508 | 2',2'-Difluoro-2'-deoxyuridine | 114248-23-6 | >95.00% | |
An active metabolite of gemcitabine | ||||
| GC46539 | 2-Chloroadenine | 1839-18-5 | >98.00% | |
A heterocyclic building block | ||||
| GC46583 | 3-Amino-2,6-Piperidinedione | 2353-44-8 | >95.00% | |
An active metabolite of (±)-thalidomide | ||||
| GC46599 | 3-hydroxy-3-methylglutaryl-Coenzyme A-d3 (ammonium salt) | - | >99.00% | |
A neuropeptide with diverse biological activities | ||||
| GC46679 | 5(S)-HETE-d8 | 330796-62-8 | >99.00% | |
An internal standard for the quantification of 5-HETE | ||||
| GC46732 | 7(S),17(S)-dihydroxy-8(E),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid | 887752-13-8 | >98.00% | |
A metabolite of DPA with anti-inflammatory properties | ||||
| GC46753 | 9(S),12(S),13(S)-TriHOME | 97134-11-7 | >98.00% | |
An oxylipin | ||||
| GC46755 | 9(S)-HODE-13C18 | - | >98.00% | |
A neuropeptide with diverse biological activities | ||||
| GC46769 | Abametapir | 1762-34-1 | >98.00% | |
A building block and an insecticide | ||||
| GC46779 | Acequinocyl | 57960-19-7 | >98.00% | |
A naphthoquinone acaricide | ||||
| GC46789 | Acetyl-L-carnitine-d3 (chloride) | 362049-62-5 | >98.50% | |
An internal standard for the quantification of L-acetylcarnitine | ||||
| GC46798 | Adapalene-d3 | 1276433-89-6 | >99.00% | |
An internal standard for the quantification of adapalene | ||||
| GC46812 | Aflatoxin G1-13C17 | 1217444-07-9 | >98.00% | |
An internal standard for the quantification of aflatoxin G 1 | ||||
| GC46814 | Aflatoxin M1-13C17 | 2707441-97-0 | >98.00% | |
A neuropeptide with diverse biological activities | ||||
| GC46820 | AHU377-d4 | 1884269-07-1 | >99.00% | |
An internal standard for the quantification of AHU377 | ||||