Metabolism(代谢)

Cat.No. 产品名称 Information

GC35308 Alpinetin

山姜素

Alpinetin, a composition of Alpinia katsumadai Hayata, has been reported to have a number of biological properties, such as antibacterial, antitumor and other important therapeutic activities. Alpinetin is a flavonoid isolated from Alpinia katsumadai Hayata, activates activates PPAR-γ, with potent anti-inflammatory activity.

GC35298 Aloe-emodin-8-O-β-D-glucopyranoside

芦荟大黄素-8-O-β-D-葡萄糖苷

Aloe-emodin-8-O-β-D-glucopyranoside 是从 Saussrurea lappa 中分离出的化合物，是温和的人类蛋白酪氨酸磷酸酶 1B (hPTP1B) 抑制剂，其 IC50 值为 26.6 μM。

GC35281 Aleglitazar

阿格列扎; R1439; RO0728804

Aleglitazar(R1439; RO-0728804)是PPAR-α/γ激动剂，IC50分别为2.8 nM/4.6 nM。

GC35250 Adenosine deaminase

腺苷脫氨酶

腺苷脱氨酶（Adenosine deaminase，ADA）是参与嘌呤代谢途径的关键酶，对腺苷和脱氧腺苷具有不可逆脱氨作用，分别转化为肌苷和脱氧肌苷。

GC35236 Acetylshikonin

乙酰紫草素

Acetylshikonin，来源于紫草根，具有抗癌、抗炎作用。Acetylshikonin 是一种非选择性的细胞色素 P450 抑制剂，对所有 P450 亚型抑制的 IC50 值范围为 1.4-4.0 μM。Acetylshikonin 是一种 AChE 抑制剂，具有很强的抗凋亡活性。

GC35201 8-Geranyloxypsoralen

8-香叶草氧基补骨脂素

8-Geranyloxypsoralen 是从葡萄柚中分离出的一种呋喃香豆素，能作为 P450 3A4 (CYP3A4) 的有效抑制剂，其 IC50 值为 3.93 μM。

GC35143 4-O-Methyl honokiol

4--O-甲基和厚朴酚

A phenol with diverse biological activities

GC35068 1-Monomyristin

1-肉豆蔻酸单甘油酯

A monoacylglycerol

GC35065 1-Linoleoyl Glycerol

一亚油酸甘油酯,1-Linoleoyl-rac-glycerol; 1-Monolinolein

A PAF-AH inhibitor

GC35024 [pTyr5] EGFR 988-993 [pTyr5] EGFR (988-993) 来源于表皮生长因子受体(EGFR 988-993)的自磷酸化位点(Tyr992)。[pTyr5] EGFR(988-993)常与催化活性低的蛋白-酪氨酸磷酸1B (PTP1B)结合。

GC34984 (R)-(-)-Rolipram

(4R)-4-[3-(环戊氧基)-4-甲氧基苯基]吡咯-2-酮,(R)-Rolipram; (-)-Rolipram

A PDE4 inhibitor

GC34980 (E)-Ferulic acid

反式阿魏酸,(E)-Coniferic acid

Trans-ferulic acid is a potent activator of AMPKunder high glucose condition.

GC45271 (±)11(12)-EET Ethanolamide

(±)11,12-EpETrE Ethanolamide

A potential cytochrome P450 metabolite of AEA

GC45270 (±)10(11)-EDP Ethanolamide

10,11-EDP-EA, 10,11-EDP epoxide, 10,11-epoxy Docosapentaenoic Ethanolamide

An ω-3 endocannabinoid epoxide and CB receptor agonist

GC45269 (±)10(11)-DiHDPA

(±)10,11-DiHDPE

An epoxygenase metabolite of DHA

GC45264 (+)-Geodin

D-地曲霉素

A fungal metabolite

GC45262 (+)-Cloprostenol methyl ester

DCloprostenol methyl ester, (+)16mChlorophenoxy tetranor PGF2α methyl ester

Lipophilic analog of (+)-cloprostenol

GC45261 (+)-Cloprostenol methyl amide

DCloprostenol methyl amide, (+)16mChlorophenoxy tetranor PGF2α methyl amide

Lipophilic analog of (+)-cloprostenol

GC45260 (+)-Cloprostenol isopropyl ester

氯前列醇异丙基酯

A more lipid soluble form of (+)-cloprostenol

GC45252 (-)-Sitagliptin Carbamoyl Glucuronide

BETA-D-吡喃葡萄糖醛酸1-[N-[(1R)-3-[5,6-二氢-3-(三氟甲基)-1,2,4-三唑并[4,3-A]吡嗪-7(8H)-基]-3-氧代-1-[(2,4,5-三氟苯基)甲基]丙基]氨基甲酸酯]

A minor phase II metabolite of (–)-sitagliptin

GC45248 (-)-FINO2 (-)-FINO2一种能够选择性激活铁死亡的有机过氧化物，用于研究铁死亡机制及抗肿瘤治疗

GC45239 δ4-Abiraterone

阿比特龙代谢物,Δ4-Abiraterone; CB-7627; Abiraterone D4A metabolite

An active metabolite of abiraterone

GC45232 β-D-Glucosamine Pentaacetate

D-氨基葡萄糖四醋酸盐

An N-acetylglucosamine derivative

GC45226 β-BHC

β-HCH, β-Hexachlorocyclohexane, β-Lindane

β-BHC is an isomer of the organochlorine pesticide γ-lindane that is a potential impurity found in commercial preparations of lindane.

GC45210 α-Linolenic Acid (sodium salt)

ALA, C18:3 (9Z,12Z,15Z), C18:3 n-3

An essential ω-3 polyunsaturated fatty acid

GC45208 α-hydroxy Metoprolol

Α-羟基美托洛尔

An active metabolite of metoprolol

GC45201 α-D-Glucose-1,6-bisphosphate (cyclohexyl ammonium salt hydrate)

Α-D-葡萄糖-1,6-二磷酸酯四(环己基铵)盐水合物,D-Glucose-1,6-diphosphate Glc-1,6-P2

α-D-Glucose-1,6-biphosphate 是葡萄糖的衍生物，用于研究碳水化合物代谢，特别是在 α-磷酸葡萄糖变位酶、β-磷酸葡萄糖变位酶以及 α- 和 β-己糖变位酶的鉴定、区分和表征方面。

GC45186 ZLN005 (hydrochloride) A small molecule activator of PGC-1α expression

GC45151 Voriconazole N-oxide

伏立康唑N-氧化物

A major metabolite of voriconazole

GC45149 VK3-OCH3

Vitamin K3-OCH3

An analog of vitamin K₃

GC45144 Vildagliptin carboxylic acid metabolite (trifluoroacetate salt)

维达列汀羧基酸代谢物三氟醋酸盐

A major metabolite of vildagliptin

GC45137 Valproic Acid Acyl-D-Glucuronide

Valproic Acid Gluclonide

A metabolite of valproic acid

GC45132 Ursodeoxycholic Acid (sodium salt)

熊去氧胆酸钠盐; Ursodeoxycholate sodium; Ursodiol sodium; UCDA sodium

A secondary bile acid

GC45126 Uric Acid (sodium salt) (Standard)

尿酸钠,Monosodium urate

An end product of purine metabolism

GC45112 UDP-β-D-Glucose (sodium salt)

NSC 20269, UDPG, UDP-Glucose, Uridine-5'-diphosphoglucose

A stereoisomer of UDP-α-D-glucose

GC45062 TNF-α Antagonist

WP9QY

A peptidomimetic of the TNF-α receptor ligand binding site

GC45060 TMP-153 A potent ACAT inhibitor

GC45036 Thioarginine (hydrobromide) L-Arginine serves as a common substrate for both nitric oxide synthase (NOS) and arginase in the cell.

GC45033 Thielavin A A natural COX and glucose-6-phosphatase inhibitor

GC45026 tetranor-PGEM

tetranor-Prostaglandin E Metabolite

A metabolite of PGE₂

GC45023 tetranor-12(R)-HETE

8(R)-HHxTrE, tetranor-12(R)-Hydroxyeicosatetraenoic Acid, 2,3,4,5-Tetranor 12(R)-HETE

A metabolite of 12(R)-HETE

GC45020 Tetrachlorohydroquinone

四氯氰醌

A metabolite of pentachlorophenol

GC45016 Ternatin

特拉廷

An anti-adipogenic cyclic peptide

GC45012 Tenofovir diphosphate (sodium salt)

PMPApp, TFV-DP

An HIV reverse transcriptase and HBV polymerase inhibitor

GC45007 Telmisartan Acyl-β-D-Glucuronide

(替米沙坦酰基)-Β-D-葡糖苷酸

A major metabolite of telmisartan

GC45001 Tazarotenic Acid

他扎罗汀酸,AGN 190299

An active metabolite of tazarotene

GC44999 Tauro-α-muricholic Acid (sodium salt)

Tauro-α-muricholate, TαMCA

An FXR receptor antagonist

GC44997 Taurolithocholic Acid 3-sulfate (sodium salt)

牛磺石胆酸钠-3-硫酸酯二钠盐

A metabolite of taurolithocholic acid

GC44996 Taurolithocholic Acid (sodium salt)

牛磺石胆酸钠

Taurolithocholic Acid (sodium salt)是一种强效的，可帮助吸收肠道中脂质和甾醇的牛磺酸共轭胆汁酸。

GC44993 Taurocholic Acid (sodium salt)

牛磺胆酸钠,Sodium taurocholate; N-Choloyltaurine sodium

Taurocholic Acid (sodium salt)是一种牛磺酸结合形式的主要胆汁酸，具有显著的生物活性作用。