Metabolism

Metabolism(代谢)

研究方向

Metabolism 相关产品(3072)

GC31299 Sch59498
CAS: 224157-99-7
Sch59498是一种有效的phosphodiesterase1c(Pde1c)抑制剂。
GC31324 PTP1B-IN-2
CAS: 1919853-46-5
纯度: >99.50%
A PTP1B inhibitor
GC31325 Saroglitazar Magnesium
CAS: 1639792-20-3
纯度: >98.50%
Saroglitazarmagnesium是一种新型的过氧化物酶体增殖物活化受体PPAR的激动剂，具有显著PPARα活性和中度PPARγ活性,在HepG2细胞中的EC50值分别为0.65pMand3nM。
GC31327 Win 58237
CAS: 158001-76-4
Win58237是一种phosphodiesterase(PDE)抑制剂，对PDEV有很强的亲和力，Ki值为170nM，具有舒张血管的作用。
GC31345 Retinol (Vitamin A1)
CAS: 68-26-8
纯度: >98.00%
视黄醇,也称为维生素A 1 ,是维生素A家族中的一种脂溶性维生素,存在于食物中,用作膳食补充剂。
GC31350 Astaxanthin
CAS: 472-61-7
纯度: >98.00%
Astaxanthin (β-Carotene-4,4'-dione, Trans-Astaxanthin), a xanthophyll carotenoid, is a nutrient with unique cell membrane actions and diverse clinical benefits with excellent safety and tolerability. Astaxanthin, a red dietary carotenoid isolated from Haematococcus pluvialis, is a modulator of PPARγ and a potent antioxidant with antiproliferative, neuroprotective and anti-inflammatory activity.
GC31355 AA26-9
CAS: 1312782-34-5
纯度: >98.00%
A pan-serine hydrolase inhibitor
GC31366 Licogliflozin (LIK066)
CAS: 1291094-73-9
纯度: >98.00%
Licogliflozin (LIK066) 是一种钠葡萄糖协同转运蛋白（SGLT1 和 SGLT2）抑制剂。
GC31377 Tofogliflozin hydrate (CSG-452 hydrate)
CAS: 1201913-82-7
纯度: >98.50% / >98.00%
A potent inhibitor of SGLT2
GC31396 Raspberry ketone (Frambione)
CAS: 5471-51-2
纯度: >99.50%
Raspberry ketone (p-Hydroxybenzyl acetone, Frambinone, Oxyphenylon, Rheosmin, Rasketone) is a natural phenolic compound that is the primary aroma compound of red raspberries. Raspberry ketone shows cardioprotective action against isoproterenol-induced myocardial infarction in rats, and the effects may be due to its PPAR-α agonistic activity.
GC31408 Indeglitazar (PPM 204)
CAS: 835619-41-5
纯度: >99.50%
Indeglitazar (PPM 204) (PPM 204) 是一种可口服的 PPAR 泛激动剂，适用于所有三种 PPARα, PPARδ和PPARγ；。
GC31422 MCH-1 antagonist 1
CAS: 1039825-68-7
MCH-1antagonist1是一种有效的黑色素浓缩激素1(MCH-1)拮抗剂，Ki值为2.6nM。MCH-1antagonist1还抑制CYP3A4，IC50为10μM。
GC31447 CVT-12012
CAS: 1018675-35-8
纯度: >98.50%
A stearoyl-CoA desaturase inhibitor
GC31450 Naveglitazar racemate
CAS: 916085-47-7
Naveglitazarracemate是Naveglitazar的外消旋体。Naveglitazar是过氧化物酶体增殖物激活受体(PPAR)α-γ双重，γ显性激动剂，在动物模型具有降低葡萄糖潜力。
GC31451 Peliglitazar racemate (BMS 426707-01 racemate)
CAS: 331744-72-0
Peliglitazar 外消旋体（BMS 426707-01 外消旋体）是 Peliglitazar 的外消旋体。
GC31452 AVE-8134
CAS: 304025-09-0
AVE-8134是PPARα的有效激动剂，对人体和啮齿类动物的PPARα的EC50值分别为100和3000nM。
GC31460 CDD3506
CAS: 197913-15-8
纯度: >98.00%
CDD3506可以通过诱导肝CYP3A的活动，来提高高密度脂蛋白胆固醇(HDL)的水平。
GC31461 Tofogliflozin (CSG452)
CAS: 903565-83-3
Tofogliflozin (CSG 452) is a novel sodium-glucose co-transporter 2(SGLT2) inhibitor with IC50 values of 2.9 nM and 8444 nM for hSGLT2 and hSGLT1, respectively.
GC31462 Arhalofenate (MBX 102)
CAS: 24136-23-0
A prodrug form of a PPARγ partial agonist
GC31464 CDD3505
CAS: 173865-33-3
纯度: >98.00%
CDD3505 is used for elevating high density lipoprotein cholesterol (HDL) by inducing hepatic cytochrome P450IIIA (CYP3A) activity.
GC31471 GSK376501A
CAS: 1010412-80-2
纯度: >99.00%
GSK376501A是一种选择性的过氧化物酶体增殖物激活受体γ(PPARγ)调节剂。可用于治疗2型糖尿病。
GC31479 BMS-819881
CAS: 1197420-05-5
BMS-819881是一种黑色素浓缩激素受体1(MCHR1)拮抗剂，结合大鼠MCHR1，Ki值为7nM。BMS-819881还有效且选择性地作用于CYP3A4，EC50为13μM.
GC31492 Vildagliptin dihydrate (LAF237 dihydrate)
CAS: 2133364-01-7
A DPP-4 inhibitor
GC31497 KD-3010
CAS: 934760-92-6
KD3010是一种具有口服活性的有效的选择性PPARδ激动剂。

分类产品列表
货号	产品名称	CAS号	纯度
GC31299	Sch59498	224157-99-7	-
GC31299	Sch59498是一种有效的phosphodiesterase1c(Pde1c)抑制剂。
GC31324	PTP1B-IN-2	1919853-46-5	>99.50%
GC31324	A PTP1B inhibitor
GC31325	Saroglitazar Magnesium	1639792-20-3	>98.50%
GC31325	Saroglitazarmagnesium是一种新型的过氧化物酶体增殖物活化受体PPAR的激动剂，具有显著PPARα活性和中度PPARγ活性,在HepG2细胞中的EC50值分别为0.65pMand3nM。
GC31327	Win 58237	158001-76-4	-
GC31327	Win58237是一种phosphodiesterase(PDE)抑制剂，对PDEV有很强的亲和力，Ki值为170nM，具有舒张血管的作用。
GC31345	Retinol (Vitamin A1)	68-26-8	>98.00%
GC31345	视黄醇,也称为维生素A 1 ,是维生素A家族中的一种脂溶性维生素,存在于食物中,用作膳食补充剂。
GC31350	Astaxanthin	472-61-7	>98.00%
GC31350	Astaxanthin (β-Carotene-4,4'-dione, Trans-Astaxanthin), a xanthophyll carotenoid, is a nutrient with unique cell membrane actions and diverse clinical benefits with excellent safety and tolerability. Astaxanthin, a red dietary carotenoid isolated from Haematococcus pluvialis, is a modulator of PPARγ and a potent antioxidant with antiproliferative, neuroprotective and anti-inflammatory activity.
GC31355	AA26-9	1312782-34-5	>98.00%
GC31355	A pan-serine hydrolase inhibitor
GC31366	Licogliflozin (LIK066)	1291094-73-9	>98.00%
GC31366	Licogliflozin (LIK066) 是一种钠葡萄糖协同转运蛋白（SGLT1 和 SGLT2）抑制剂。
GC31377	Tofogliflozin hydrate (CSG-452 hydrate)	1201913-82-7	>98.50% / >98.00%
GC31377	A potent inhibitor of SGLT2
GC31396	Raspberry ketone (Frambione)	5471-51-2	>99.50%
GC31396	Raspberry ketone (p-Hydroxybenzyl acetone, Frambinone, Oxyphenylon, Rheosmin, Rasketone) is a natural phenolic compound that is the primary aroma compound of red raspberries. Raspberry ketone shows cardioprotective action against isoproterenol-induced myocardial infarction in rats, and the effects may be due to its PPAR-α agonistic activity.
GC31408	Indeglitazar (PPM 204)	835619-41-5	>99.50%
GC31408	Indeglitazar (PPM 204) (PPM 204) 是一种可口服的 PPAR 泛激动剂，适用于所有三种 PPARα, PPARδ和PPARγ；。
GC31422	MCH-1 antagonist 1	1039825-68-7	-
GC31422	MCH-1antagonist1是一种有效的黑色素浓缩激素1(MCH-1)拮抗剂，Ki值为2.6nM。MCH-1antagonist1还抑制CYP3A4，IC50为10μM。
GC31447	CVT-12012	1018675-35-8	>98.50%
GC31447	A stearoyl-CoA desaturase inhibitor
GC31450	Naveglitazar racemate	916085-47-7	-
GC31450	Naveglitazarracemate是Naveglitazar的外消旋体。Naveglitazar是过氧化物酶体增殖物激活受体(PPAR)α-γ双重，γ显性激动剂，在动物模型具有降低葡萄糖潜力。
GC31451	Peliglitazar racemate (BMS 426707-01 racemate)	331744-72-0	-
GC31451	Peliglitazar 外消旋体（BMS 426707-01 外消旋体）是 Peliglitazar 的外消旋体。
GC31452	AVE-8134	304025-09-0	-
GC31452	AVE-8134是PPARα的有效激动剂，对人体和啮齿类动物的PPARα的EC50值分别为100和3000nM。
GC31460	CDD3506	197913-15-8	>98.00%
GC31460	CDD3506可以通过诱导肝CYP3A的活动，来提高高密度脂蛋白胆固醇(HDL)的水平。
GC31461	Tofogliflozin (CSG452)	903565-83-3	-
GC31461	Tofogliflozin (CSG 452) is a novel sodium-glucose co-transporter 2(SGLT2) inhibitor with IC50 values of 2.9 nM and 8444 nM for hSGLT2 and hSGLT1, respectively.
GC31462	Arhalofenate (MBX 102)	24136-23-0	-
GC31462	A prodrug form of a PPARγ partial agonist
GC31464	CDD3505	173865-33-3	>98.00%
GC31464	CDD3505 is used for elevating high density lipoprotein cholesterol (HDL) by inducing hepatic cytochrome P450IIIA (CYP3A) activity.
GC31471	GSK376501A	1010412-80-2	>99.00%
GC31471	GSK376501A是一种选择性的过氧化物酶体增殖物激活受体γ(PPARγ)调节剂。可用于治疗2型糖尿病。
GC31479	BMS-819881	1197420-05-5	-
GC31479	BMS-819881是一种黑色素浓缩激素受体1(MCHR1)拮抗剂，结合大鼠MCHR1，Ki值为7nM。BMS-819881还有效且选择性地作用于CYP3A4，EC50为13μM.
GC31492	Vildagliptin dihydrate (LAF237 dihydrate)	2133364-01-7	-
GC31492	A DPP-4 inhibitor
GC31497	KD-3010	934760-92-6	-
GC31497	KD3010是一种具有口服活性的有效的选择性PPARδ激动剂。