Home >> Signaling Pathways >> Proteases

Proteases(蛋白酶)

Proteases, also known as peptidases or proteolytic enzymes, consists of a large number of enzymes catalyzing the hydrolysis of peptide bonds and subsequently resulting in the degradation of protein substrates into amino acids. Proteases are involved in a wide range of human diseases, including cancer, neurodegenerative disorders, inflammatory diseases and cardiovascular diseases. Thus numerous proteases inhibitors (small molecules and proteins) have been identified to block activity of proteases. Proteases inhibitors can be classified into different types based on the class of proteases they inhibit through two general mechanisms, irreversible “trapping” reactions and reversible tight-binding reactions. Proteases inhibitors have been used as diagnostic or therapeutic agents for the treatment of proteases-related diseases.

Products for  Proteases

  1. Cat.No. 产品名称 Information
  2. GC64336 2-Hydroxyemodin

    2-羟基大黄素

    2-Hydroxyemodin 是肝微粒体中大黄素的活性代谢物。大黄素是一种存在于真菌代谢物和大黄成分中的蒽醌。在没有激活系统的情况下,2-Hydroxyemodin 对鼠伤寒沙门氏菌 TA1537 具有诱变作用。
  3. GC70560 2-Hydroxyestradiol-d5 2-Hydroxyestradiol-d5是氘标记的2-羟基雌二醇。
  4. GC38190 2-Hydroxyhexanoic acid

    Α-羥己酸

    2-Hydroxyhexanoic acid (2-Hydroxyhexanoic acid) is an endogenous metabolite.
  5. GC19715 2-hydroxyisobutyrate

    2-甲基-2-羟基丙酸

    2-羟基异丁酸是一种内源性代谢物。
  6. GC68519 2-Hydroxyisobutyric acid-d6 2-Hydroxyisobutyric acid-d6 是 2-Hydroxyisobutyric acid 的氘代物。2-Hydroxyisobutyric acid 是一种内源性代谢产物。
  7. GC60476 2-hydroxymethyl benzoic acid

    2-羟甲基苯甲酸

    2-hydroxymethylbenzoicacid是一种内源性代谢产物。
  8. GC33742 2-Hydroxyphenylacetic acid

    邻羟基苯乙酸

    2-Hydroxyphenylacetic acid (2-Hydroxybenzeneacetate, ortho-Hydroxyphenylacetic acid) is a substrate of the enzyme oxidoreductases in the pathway styrene degradation.
  9. GC30136 2-Ketoglutaric acid

    α-酮戊二酸; Alpha-Ketoglutaric acid

    An intermediate in the citric acid cycle
  10. GC72546 2-Ketoglutaric acid-13C5 2-Ketoglutaric acid-13C5是13C标记的2-酮戊二酸。
  11. GC72547 2-Ketoglutaric acid-d6 2-Ketoglutaric acid-d6是氘标记的2-酮戊二酸。
  12. GC39761 2-Mercaptobenzothiazole

    2-巯基苯并噻唑

    2-Mercaptobenzothiazole (Benzothiazole-2-thiol, 2-MBT, Mercapto-2-benzothiazole) is an exceptionally potent inhibitor of banana polyphenoloxidase and can significantly delay the onset of substrate oxidation at concentrations as low as 100 nM.
  13. GC62777 2-Methoxy-4-vinylphenol

    4-乙烯基-2-甲氧基苯酚

    2-Methoxy-4-vinylphenol (2M4VP) 是天然的发芽抑制剂,具有抗炎活性。
  14. GC34179 2-Methoxybenzoic acid (NSC 3778)

    邻甲氧基苯甲酸,NSC 3778; O-Methylsalicylic acid; Salicylic acid methyl ether

    2-Methoxybenzoic acid (o-Anisic acid) is a flavouring agent.
  15. GC15084 2-Methoxyestradiol (2-MeOE2)

    二甲氧基雌二醇; 2-ME2; NSC-659853

    2-Methoxyestradiol (2-MeOE2/2-Me)是一种HIF-1α抑制剂。
  16. GC33810 2-Methoxyestrone

    2-甲基雌酮

    An active metabolite of estrone
  17. GC70361 2-Methoxyestrone-d4 2-Methoxyestrone-d4是氘标记的2-甲氧基雌酮。
  18. GC39776 2-Methylacetophenone

    邻甲基苯乙酮

    2-Methylacetophenone 是一种内源性代谢产物。
  19. GC60477 2-Methylbenzaldehyde

    2-甲基苯甲醛

    2-Methylbenzaldehyde是一种内源性代谢产物。
  20. GC60478 2-Methylbenzoxazole

    2-甲基苯并唑

    2-Methylbenzoxazole是一种内源性代谢产物。
  21. GC74710 2-Methylbutyrylcarnitine chloride 2-Methylbutyrylcarnitine chloride是一种肠道微生物代谢产物,与血小板中的整合素α2β1结合,增强细胞质磷脂酶A2(cPLA2)的活化和血小板的过度反应性。
  22. GC60479 2-Methylcitric acid

    2-甲基柠檬酸,Methylcitric acid

    An endogenous tricarboxylic acid
  23. GC60480 2-Methylcitric acid trisodium

    Methylcitric acid trisodium

    An endogenous tricarboxylic acid
  24. GC70373 2-Methylcitric acid-d3 2-Methylcitric acid-d3是氘标记的2-甲基柠檬酸。
  25. GC62779 2-Methylcyclohexanone

    2-甲基环己酮

    2-Methylcyclohexanone 是一种内源性代谢产物。
  26. GC30671 2-Methylpentanedioic acid

    2-甲基戊二酸

    2-Methylglutaric acid (alpha-Methylglutaric acid) is a metabolite of succinic acid, a citric acid cycle intermediate.

  27. GC31435 2-Methylsuccinic acid

    甲基丁二酸

    2-Methylsuccinic acid (Pyrotartaric acid, 2-methylbutanedioic acid, propane-1,2-dicarboxylic acid, Methylsuccinate) is a normal metabolite found in human fluids.

  28. GC60481 2-Methylvaleric acid

    2-甲基戊酸,2-Methylpentanoic acid

    2-Methylpentanoic acid (2-Methylvaleric acid, Methylpropylacetic acid) is a short-chain fatty acid that exists in various foods including cheeses, cherimoya, lamb and mutton, and so on. 2-Methylpentanoic acid is a flavor compound used for food-flavor ingredient, fragrances.
  29. GC17937 2-MPPA

    GPI-5693

    2-MPPA (GPI-5693) 是一种具有口服活性的选择性谷氨酸羧肽酶 II (GCP II; PSMA) 抑制剂,IC50 为 90 nM。
  30. GC30720 2-Naphthol

    β-萘酚

    2-Naphthol (2-Hydroxynaphthalene, 2-Naphthalenol, beta-Naphthol, Naphth-2-ol, β-naphthol), a potential antinematodal drug, is a widely used intermediate for the production of dyes and other compounds.
  31. GC39845 2-Naphthoxyacetic acid

    2-萘氧乙酸

    2-Naphthoxyacetic acid 是一种内源性代谢产物。
  32. GC70763 2-NP-AMOZ 2-NP-AMOZ是AMOZ(抗生素呋喃他酮的代谢物)的2-硝基苯衍生物,可用于检测蛋白结合的AMOZ。
  33. GC39527 2-O-Methylcytosine

    4-氨基-2-甲氧基嘧啶

    2-O-Methylcytosine,一种 O-烷基化类似物和 DNA 的加合物,属于受损的核碱基。
  34. GC42189 2-oxo Clopidogrel

    甲基(2-氯苯基)(2-氧代-2,6,7,7ALPHA-四氢噻吩并[3,2-C]吡啶-5(4H)-基)乙酸酯

    An intermediary metabolite of clopidogrel
  35. GC30622 2-Oxo-3-phenylpropanoic acid

    苯丙酮酸

    2-Oxo-3-phenylpropanoic acid (Phenylpyruvic acid) is used in the synthesis of 3-phenyllactic acid (PLA) by lactate dehydrogenase.
  36. GC30629 2-Oxobutanoic acid

    2-丁酮酸

    2-Oxobutanoic acid (2-Oxobutyrate, 2-ketobutyric acid, 2-oxobutyric acid, alpha-ketobutyric acid, α-ketobutyric acid) is a substance that is involved in the metabolism of many amino acids as well as propanoate metabolism and C-5 branched dibasic acid metabolism.

  37. GC38276 2-Oxosuccinic acid

    草酰乙酸; 2-Oxosuccinic acid

    2-Oxosuccinic acid(草酰乙酸)是一种α-酮酸,在柠檬酸循环的第一步中草酰乙酸与乙酰辅酶A和水反应形成柠檬酸盐,并在最后一步中通过L-苹果酸的氧化再生。
  38. GC30713 2-Oxovaleric acid

    2-戊酮酸

    2-Oxovalericacid是在人体血液中发现的一种酮酸。

  39. GC60018 2-Phenylacetaldehyde

    苯乙醛

    Phenylacetaldehyde (Hyacinthin, Phenylethanal) is an organic compound used in the synthesis of fragrances and polymers.
  40. GC60483 2-Phenylacetamide

    2-苯乙酰胺

    A metabolite of L-phenylalanine
  41. GC62784 2-Phenylbutanoic acid

    2-苯基丁酸

    2-Phenylbutyric acid (alpha-Phenylbutyric acid, alpha-phenylbutyrate, alpha-Ethylphenylacetic acid), belongs to the class of organic compounds known as phenylpropanes, is used as an anticholesteremic.
  42. GC60485 2-Phenylglycine

    2-氨基-2-苯基乙酸,DL-α-Phenylglycine

    2-Phenylglycine(DL-α-Phenylglycine)是在W2至W4泌乳期间母乳中的代谢产物。
  43. GC31611 2-Phenylpropionic acid

    2-苯基丙酸

    2-Phenylpropionic acid (2-Phenylpropionate, Hydratropic acid, α-methyl-α-toluic acid) is an intermediate in alpha-Methylstyrene (2-phenylpropylene) metabolism.
  44. GC35095 2-Phospho-L-ascorbic acid trisodium salt

    L-抗坏血酸-2-磷酸三钠盐; 2-Phospho-L-ascorbic acid trisodium

    Sodium L-ascorbyl-2-phosphate (Sodium ascorbyl monophosphate, Sodium ascorbyl phosphate, SAP) is specifically produced for use as a stabilized source of vitamin C in cosmetic products.

  45. GC60486 2-Piperidone

    2-氮己环酮

    2-Piperidone是一种内源性代谢产物。
  46. GC19539 2-Pyrrolidinone

    2-吡咯烷酮,2-Pyrrolidone

  47. GC42193 2-Thenoyltrifluoroacetone

    2-噻吩甲酰三氟丙酮,HTTA; TTA; TTFA

    An inhibitor of respiration
  48. GC60487 2-Thiophenecarboxaldehyde

    2-噻吩甲醛

    2-Thiophenecarboxaldehyde是一种内源性代谢产物。

  49. GC42082 20-carboxy Leukotriene B4

    20-羧基白三烯B4

    A LTB4 metabolite
  50. GC35075 20-HETE

    20-羟基二十碳-5Z,8Z,11Z,14Z-四烯酸

    A cytochrome P450 (CYP450) metabolite of arachidonic acid

  51. GC41421 20-hydroxy Leukotriene B4

    20-羟基白三烯B4

    A LTB4 metabolite

Items 401 to 450 of 4106 total

per page

Set Descending Direction