Proteases
Proteases(蛋白酶)
Proteases, also known as peptidases or proteolytic enzymes, consists of a large number of enzymes catalyzing the hydrolysis of peptide bonds and subsequently resulting in the degradation of protein substrates into amino acids. Proteases are involved in a wide range of human diseases, including cancer, neurodegenerative disorders, inflammatory diseases and cardiovascular diseases. Thus numerous proteases inhibitors (small molecules and proteins) have been identified to block activity of proteases. Proteases inhibitors can be classified into different types based on the class of proteases they inhibit through two general mechanisms, irreversible “trapping” reactions and reversible tight-binding reactions. Proteases inhibitors have been used as diagnostic or therapeutic agents for the treatment of proteases-related diseases.
- Aminopeptidase(21)
- ACE(75)
- Calpains(11)
- Carboxypeptidase(9)
- Cathepsin(65)
- DPP-4(18)
- Elastase(25)
- Gamma Secretase(50)
- HCV Protease(39)
- HSP(105)
- HIV Integrase(30)
- HIV Protease(35)
- MMP(195)
- NS3/4a protease(4)
- Serine Protease(19)
- Thrombin(47)
- Urokinase(2)
- Cysteine Protease
- Tyrosinases(50)
- Other Proteases(15)
- 15-PGDH(1)
- Acetyl-CoA Carboxylase(14)
- Acyltransferase(64)
- Aldehyde Dehydrogenase (ALDH)(30)
- Aminoacyl-tRNA Synthetase(9)
- ATGL(1)
- Dipeptidyl Peptidase(49)
- Drug Metabolite(513)
- E1/E2/E3 Enzyme(92)
- Endogenous Metabolite(1768)
- FABP(9)
- Farnesyl Transferase(20)
- Glutaminase(17)
- Glutathione Peroxidase(35)
- Isocitrate Dehydrogenase (IDH)(28)
- Lactate Dehydrogenase(19)
- Lipoxygenase(274)
- Mitochondrial Metabolism(260)
- NEDD8-activating Enzyme(6)
- Neprilysin(12)
- PAI-1(14)
- Ser/Thr Protease(49)
- Tryptophan Hydroxylase(12)
- Xanthine Oxidase(18)
- MALT1(10)
- Caspase(117)
- PCSK9(13)
- ADAMTS(1)
- Density Lipoprotein
- TrxR(1)
- DGK(3)
Proteases 相关产品(4079)
- GC41736(S)-Dibutyl 3-Hydroxybutyl PhosphateCAS: 2108602-99-7纯度: >95.00%
A compound produced from tributyl phosphate
- GC41776Triolein (1,2,3-Trioleoyl-rac-glycerol)CAS: 122-32-7纯度: >80.00% / >95.00% / >99.00%
Triolein (1,2,3-Trioleoyl-rac-glycerol)是一种甘油三酯，被用于研究脂质代谢相关过程。Triolein可作为模型底物来探究脂肪在体内的消化、吸收以及转运等情况。
- GC418251,2-Dipalmitoyl-sn-glycero-3-phosphate (sodium salt)CAS: 169051-60-9纯度: >98.00% / >99.00%
1,2-Dipalmitoyl-sn-glycero-3-phosphate (sodium salt)（16:0/16:0-PA）是一种磷脂，含有插入到sn-1和sn-2位置的长链（16:0）棕榈酸，能够用于制备脂质体、胶束和人工膜。
- GC4189913(S)-HpOTrECAS: 67597-26-6纯度: >98.00%
A product of soybean LO-2 metabolism of α-linolenic acid
- GC4190013(S)-HpOTrE(γ)CAS: 121107-97-9纯度: >98.00%
Produced by the action of soybean LO-1 on γ-linolenic acid
- GC4191113-epi-12-oxo Phytodienoic AcidCAS: 71606-07-0纯度: >95.00%
A lipoxygenase metabolite of α-linolenic acid
- GC4192615(S)-HETE-biotinCAS: 1217461-45-4纯度: >95.00%
Used to detect 15(S)-HETE binding proteins and/or receptors
- GC4193715-keto-17-phenyl trinor Prostaglandin F2α ethyl amideCAS: 1163135-96-3纯度: >98.00%
A potential metabolite of Bimatoprost
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC41722 | (R,S)-Carvedilol Glucuronide | 114869-83-9 | >95.00% | |
A phase II metabolite of carvedilol | ||||
| GC41736 | (S)-Dibutyl 3-Hydroxybutyl Phosphate | 2108602-99-7 | >95.00% | |
A compound produced from tributyl phosphate | ||||
| GC41765 | 1,2,3-Tri-13(Z)-Docosenoyl-rac-glycerol | 2752-99-0 | >98.00% | |
A triacylglycerol | ||||
| GC41767 | 1,2,3-Triarachidonoyl-rac-glycerol | 620-64-4 | >98.00% | |
A triacylglycerol | ||||
| GC41768 | 1,2,3-Tridecanoyl-rac-glycerol | 621-71-6 | >98.00% | |
A triacylglycerol | ||||
| GC41770 | 1,2,3-Trieicosapentaenoyl-rac-glycerol | 99660-94-3 | - | |
A polyunsaturated triacylglycerol | ||||
| GC41774 | 1,2,3-Trimyristoyl-rac-glycerol | 555-45-3 | >95.00% | |
A triacylglycerol | ||||
| GC41776 | Triolein (1,2,3-Trioleoyl-rac-glycerol) | 122-32-7 | >80.00% / >95.00% / >99.00% | |
Triolein (1,2,3-Trioleoyl-rac-glycerol)是一种甘油三酯，被用于研究脂质代谢相关过程。Triolein可作为模型底物来探究脂肪在体内的消化、吸收以及转运等情况。 | ||||
| GC41778 | 1,2,3-Tripalmitoyl-rac-glycerol | 555-44-2 | >98.00% | |
A triacylglycerol | ||||
| GC41804 | 1,2-Dimyristoyl-sn-glycero-3-PE | 998-07-2 | >97.00% | |
A phospholipid | ||||
| GC41825 | 1,2-Dipalmitoyl-sn-glycero-3-phosphate (sodium salt) | 169051-60-9 | >98.00% / >99.00% | |
1,2-Dipalmitoyl-sn-glycero-3-phosphate (sodium salt)（16:0/16:0-PA）是一种磷脂，含有插入到sn-1和sn-2位置的长链（16:0）棕榈酸，能够用于制备脂质体、胶束和人工膜。 | ||||
| GC41837 | 1,3,7-Trimethyluric Acid | 5415-44-1 | >98.00% | |
A metabolite of caffeine | ||||
| GC41882 | 12(S)-HETrE | 72710-10-2 | >98.00% | |
An inhibitor of platelet activation | ||||
| GC41896 | 13(S)-HODE-biotin | 1176496-97-1 | >98.00% | |
A biotinylated PUFA | ||||
| GC41897 | 13(S)-HOTrE | 87984-82-5 | >98.00% | |
A 15-LO product derived from GLA | ||||
| GC41898 | 13(S)-HOTrE(γ) | 74784-20-6 | >98.00% | |
A 15-LO product derived from GLA | ||||
| GC41899 | 13(S)-HpOTrE | 67597-26-6 | >98.00% | |
A product of soybean LO-2 metabolism of α-linolenic acid | ||||
| GC41900 | 13(S)-HpOTrE(γ) | 121107-97-9 | >98.00% | |
Produced by the action of soybean LO-1 on γ-linolenic acid | ||||
| GC41911 | 13-epi-12-oxo Phytodienoic Acid | 71606-07-0 | >95.00% | |
A lipoxygenase metabolite of α-linolenic acid | ||||
| GC41925 | 15(S)-HETE Ethanolamide | 161744-53-2 | >98.00% | |
A CB 1 receptor ligand and FAAH inhibitor | ||||
| GC41926 | 15(S)-HETE-biotin | 1217461-45-4 | >95.00% | |
Used to detect 15(S)-HETE binding proteins and/or receptors | ||||
| GC41927 | 15(S)-HETrE | 92693-02-2 | >98.00% | |
A 5-LO inhibitor | ||||
| GC41937 | 15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide | 1163135-96-3 | >98.00% | |
A potential metabolite of Bimatoprost | ||||
| GC41938 | 15-Lipoxygenase Inhibitor 1 | 928853-86-5 | >99.50% | |
An inhibitor of 15-LO | ||||