Proteases(蛋白酶)

Proteases, also known as peptidases or proteolytic enzymes, consists of a large number of enzymes catalyzing the hydrolysis of peptide bonds and subsequently resulting in the degradation of protein substrates into amino acids. Proteases are involved in a wide range of human diseases, including cancer, neurodegenerative disorders, inflammatory diseases and cardiovascular diseases. Thus numerous proteases inhibitors (small molecules and proteins) have been identified to block activity of proteases. Proteases inhibitors can be classified into different types based on the class of proteases they inhibit through two general mechanisms, irreversible “trapping” reactions and reversible tight-binding reactions. Proteases inhibitors have been used as diagnostic or therapeutic agents for the treatment of proteases-related diseases.

Products for Proteases

Cat.No. 产品名称 Information
GC47430 Hexanoyl-L-carnitine (chloride)
Caproyl-L-Carnitine, L-Caproylcarnitine, CAR 6:0, C6:0 Carnitine, L-Carnitine caproyl ester, L-Carnitine hexanoyl ester, L-Hexanoylcarnitine
A medium-chain acylcarnitine
GC47399 Geranylgeranoic Acid
GGA

An isoprenoid with anticancer activity
GC47370 Fosinopril (sodium salt)
福辛普利钠; SQ28555
A prodrug form of fosinoprilat
GC47366 Flurbiprofen-d3
氟比洛芬-D3氘代物,dl-Flurbiprofen-d3
An internal standard for the quantification of flurbiprofen
GC47351 Fingolimod-d4
芬戈莫德-D4,FTY720 free based-d4
An internal standard for the quantification of fingolimod
GC47339 Fenpropimorph
顺-4-叔丁基苯基(-2-甲基丙基)-2,6-二甲基吗啉
A fungicide that inhibits the sterol pathway
GC47330 Faldaprevir-d6
BI-201335-d6
Faldaprevir-d6 是氘标记的 Faldaprevir。
GC47326 Etoxazole
乙螨唑
An organofluorine acaricide
GC47323 Etofenamate-d4
依托芬那酯 d4
An internal standard for the quantification of etofenamate
GC47320 Ethynyl Estradiol 3-β-D-Glucuronide (hydrate)
17α-Ethynylestradiol 3-Glucuronide
A metabolite of ethynyl estradiol
GC47312 Etherolenic Acid
(9Z,11E,1'E,3'Z)-12-(1',3'-hexadenyloxy)-9,11-Dodecadienoic Acid
A divinyl ether oxylipin
GC47274 DS44960156 An MTHFD2 inhibitor
GC47243 DL-Carnitine-d9 (chloride)
DL-肉碱盐酸盐-D9氘代,DL-Carnitine-d9 chloride
An internal standard for the quantification of carnitine
GC47240 Diquat-d4 (bromide) A neuropeptide with diverse biological activities
GC47239 Diquat-d12 (bromide) A neuropeptide with diverse biological activities
GC47238 Diquat (bromide)
敌草快
An herbicide
GC47196 Desloratadine-d4
Sch34117-d4
An internal standard for the quantification of desloratadine
GC47195 Desethylchloroquine-d4
N-Desethylchloroquine-d4
An internal standard for the quantification of desethylchloroquine
GC47193 Desethyl Hydroxychloroquine-d4
Desethylhydroxychloroquine-d4
An internal standard for the quantification of desethyl hydroxychloroquine
GC47178 Decanoyl-L-carnitine-d3 (chloride)
癸酰基-L-肉碱-d3
A neuropeptide with diverse biological activities
GC47177 Decanoyl-L-carnitine (hydrate)
CAR 10:0, C10:0 Carnitine, L-Carnitine decanoyl ester, (-)-Decanoylcarnitine, L-Decanoylcarnitine
A neuropeptide with diverse biological activities
GC47176 Decanoyl-Coenzyme A (hydrate)
Decanoyl-CoA
A neuropeptide with diverse biological activities
GC47173 Darunavir-d9
九氘代地瑞拉为,TMC114-d9; UIC-94017-d9
An internal standard for the quantification of darunavir
GC47160 Cystamine-d8 (hydrochloride) A neuropeptide with diverse biological activities
GC47123 Coumarin-Quinone Conjugate A fluorescent substrate for NADH:ubiquinone oxidoreductases
GC47117 Colchicine-d6
秋水仙素 d6
An internal standard for the quantification of colchicine
GC47116 Coenzyme Q10-d6
辅酶Q10-D6,CoQ10-d6; Ubiquinone-10-d6
An internal standard for the quantification of CoQ₁₀
GC47114 Coenzyme A (lithium salt hydrate)
CoA
An essential cofactor in enzymatic acetyl transfer reactions
GC47096 Citrinin-13C13
(-)-Citrinin-13C13, CTN-13C13
A neuropeptide with diverse biological activities
GC47087 Cilastatin-15N-d3
MK0791-15N,d3
A neuropeptide with diverse biological activities
GC47065 CAY10773 A derivative of sorafenib
GC47042 Carfilzomib-d8
来那度胺-D8
An internal standard for the quantification of carfilzomib
GC47040 Carebastine-d5
卡依巴司丁 d5
An internal standard for the quantification of carebastine
GC47022 Camostat-d6 (hydrochloride) A neuropeptide with diverse biological activities
GC46972 Butyryl-L-carnitine-d3 (chloride)
丁酰基-L-肉碱-d3 （盐酸盐）
An internal standard for the quantification of butyryl-L-carnitine
GC46955 Bromoenol lactone-d7
(6E)-Bromoenol lactone-d7
A neuropeptide with diverse biological activities
GC46943 Boscalid
啶酰菌胺
A broad-spectrum carboxamide fungicide
GC46936 Boceprevir-d9
波普瑞韦,EBP 520-d9; SCH 503034-d9
An internal standard for the quantification of boceprevir
GC46893 Atranorin
荔枝素
A depside lichen metabolite with diverse biological activities
GC46890 Atorvastatin-d5 (calcium salt)
阿托伐他汀 d5 (1/2钙盐)
An internal standard for the quantification of atorvastatin
GC46887 Atazanavir-d6
阿扎那韦D6,BMS-232632-d6
An internal standard for the quantification of atazanavir
GC46885 Asperglaucide
金色酰胺醇酯,Asperglaucide
An amide with diverse biological activities
GC46883 AS-2077715 An inhibitor of fungal complex III
GC46854 Anastrozole-d12
ZD1033-d12
An internal standard for the quantification of anastrozole
GC46841 Amiloride (hydrochloride) (hydrate)
MK-870
具有多种生物活性的神经肽
GC46820 AHU377-d4
AHU-377-d4
An internal standard for the quantification of AHU377
GC46814 Aflatoxin M1-13C17
AFM1-13C17
A neuropeptide with diverse biological activities
GC46812 Aflatoxin G1-13C17
黄曲霉毒素G1-(全碳-13)
An internal standard for the quantification of aflatoxin G₁
GC46798 Adapalene-d3
阿达帕林 d3
An internal standard for the quantification of adapalene
GC46789 Acetyl-L-carnitine-d3 (chloride)
O-Acetyl-L-carnitine-d3-1 hydrochloride
An internal standard for the quantification of L-acetylcarnitine