Metabolism
Metabolism(代谢)
- PPAR(219)
- 5-alpha Reductase(11)
- 5-Lipoxygenase(11)
- Adenosine Deaminase(10)
- Aminopeptidase(15)
- C14ɑ demethylase(2)
- Carbonic Anhydrase(55)
- CETP(9)
- Cholesterol absorption(1)
- CPT1(2)
- CYP3A/CYP450(22)
- Dehydrogenase(43)
- DHFR(7)
- DGAT(10)
- Dopamine β-hydroxylase(10)
- Enolase(5)
- FAAH(38)
- Factor Xa(61)
- Ferroptosis(198)
- Folate Analogue(2)
- Glucokinase(18)
- HLE(1)
- HMG-CoA Reductase(37)
- HSP(100)
- IDO(46)
- KRAS-PDEδ(3)
- MAO(6)
- Metabolic Enzymes(6)
- Neuronal Metabolism(8)
- Oxidative Phosphorylation(26)
- P450(456)
- PDE(250)
- Phospholipase(130)
- Procollagen C Proteinase(1)
- Saccharometabolism(1)
- SCD(20)
- SGLT(29)
- TPH(4)
- Transferase(26)
- Energy Metabolism
- Inorganic Ions
- ALP(1)
- Carbohydrates(36)
- Uric Acid
- Muscle Metabolism
- MDA
- MPO
- Transaminase(3)
- Glutathione Reductase(1)
- Thioredoxin Reductase
- Catalase(15)
- monooxygenase(1)
- PKM2(1)
- Aldehyde dehydrogenase(1)
- Squalene synthase(1)
- Hydrolase(17)
- ornithine decarboxylase(1)
- Amino acid metabolism(3)
- phosphatases(103)
- Pyruvate kinase(13)
- Others(64)
- MGL(1)
- Galactosidase(2)
- 12-Lipoxygenase(1)
- Fatty Acid Synthase (FASN)(9)
- Dihydroorotate Dehydrogenase(13)
- Bile Acids & Microbiome(131)
- Bone Growth & Remodeling(55)
- Carbohydrate Metabolism(166)
- Cofactors & Vitamins(87)
- Dyslipidemias(109)
- Inborn Errors of Metabolism(100)
- Metabolic Syndrome(22)
- Necroptosis(12)
- Necrosis(19)
- Nutrient Sensing(14)
- Phosphodiesterase(34)
- Reproductive Biology(184)
- Thermogenesis(10)
- Sterol Biosynthesis(42)
- Prolyl Hydroxylation Enzymes(2)
- Biliary System(16)
- Metabolic Disease(5)
- Fat Mass and Obesity-associated Protein (FTO)(5)
- SHIP(1)
- FOXO
- Furin(1)
- Liposome(8)
- MetAP
- PGC-1α
- PI5P4K(1)
- Metabolic Diseases(2)
Metabolism 相关产品(3072)
- GC34622IACS-8968 R-enantiomerCAS: 2239305-67-8纯度: >98.00%
IACS-8968(R-enantiomer)是IACS-8968的R型对映异构体。IACS-8968是IDO和TDO的双抑制剂，其pIC50s值分别为6.43，<5。
- GC34623IACS-8968 S-enantiomerCAS: 2239305-70-3纯度: >98.00%
IACS-8968(S-enantiomer)是IACS-8968的S型对映异构体。IACS-8968是IDO和TDO的双抑制剂，其pIC50s值分别为6.43，<5。
- GC34634JG-98CAS: 1456551-16-8纯度: >98.00%
JG-98 is an allosteric inhibitor of Hsp70 that binds tightly to a deep pocket that is conserved in members of the Hsp70 family. JG-98 induces classical apoptosis features, including morphological changes consistent with programmed cell death and positive annexin staining. JG-98 exhibits anticancer activity.
- GC34705PDE2/PDE10-IN-1CAS: 1426833-08-0纯度: >99.50%
PDE2/PDE10-IN-1是一种磷酸二酯酶PDE2和PDE10抑制剂，IC50分别为29和480nM。
- GC34980(E)-Ferulic acidCAS: 537-98-4纯度: >99.00%
Trans-ferulic acid is a potent activator of AMPKunder high glucose condition.
- GC35024[pTyr5] EGFR 988-993CAS: 159453-08-4
[pTyr5] EGFR (988-993) 来源于表皮生长因子受体(EGFR 988-993)的自磷酸化位点(Tyr992)。[pTyr5] EGFR(988-993)常与催化活性低的蛋白-酪氨酸磷酸1B (PTP1B)结合。
- GC352018-GeranyloxypsoralenCAS: 7437-55-0纯度: >98.00%
8-Geranyloxypsoralen 是从葡萄柚中分离出的一种呋喃香豆素，能作为 P450 3A4 (CYP3A4) 的有效抑制剂，其 IC50 值为 3.93 μM。
- GC35236AcetylshikoninCAS: 24502-78-1纯度: >98.00%
Acetylshikonin，来源于紫草根，具有抗癌、抗炎作用。Acetylshikonin 是一种非选择性的细胞色素 P450 抑制剂，对所有 P450 亚型抑制的 IC50 值范围为 1.4-4.0 μM。Acetylshikonin 是一种 AChE 抑制剂，具有很强的抗凋亡活性。
- GC35250Adenosine deaminaseCAS: 9026-93-1纯度: >98.00%
腺苷脱氨酶（Adenosine deaminase，ADA）是参与嘌呤代谢途径的关键酶，对腺苷和脱氧腺苷具有不可逆脱氨作用，分别转化为肌苷和脱氧肌苷。
- GC35281AleglitazarCAS: 475479-34-6纯度: >99.00%
Aleglitazar(R1439; RO-0728804)是PPAR-α/γ激动剂，IC50分别为2.8 nM/4.6 nM。
- GC35298Aloe-emodin-8-O-β-D-glucopyranosideCAS: 33037-46-6
Aloe-emodin-8-O-β-D-glucopyranoside 是从 Saussrurea lappa 中分离出的化合物，是温和的人类蛋白酪氨酸磷酸酶 1B (hPTP1B) 抑制剂，其 IC50 值为 26.6 μM。
- GC35308AlpinetinCAS: 36052-37-6纯度: >98.00%
Alpinetin, a composition of Alpinia katsumadai Hayata, has been reported to have a number of biological properties, such as antibacterial, antitumor and other important therapeutic activities. Alpinetin is a flavonoid isolated from Alpinia katsumadai Hayata, activates activates PPAR-γ, with potent anti-inflammatory activity.
- GC35349Angeloylgomisin HCAS: 66056-22-2
Angeloylgomisin H 是一种木脂素类化合物，可从五味子 (Schisandra rubriflora) 中提取。Angeloylgomisin H 通过激活 PPAR-γ 来改善胰岛素刺激的葡萄糖摄取潜力。
- GC35358AnkaflavinCAS: 50980-32-0
Ankaflavin 是从Monascus-Fermented 红米中提取得到的，是PPARγ 的激动剂，具有抗炎活性。Ankaflavin 具有选择性的细胞毒性作用，诱导癌细胞死亡。
- GC35371AP-III-a4 hydrochlorideCAS: 2070014-95-6
AP-III-a4 hydrochloride是第一个非底物类似物烯醇化酶抑制剂（IC 50 = 0.576μM）。
- GC35398Arteannuin BCAS: 50906-56-4纯度: >98.00%
A precursor to artemisinin with diverse biological activities
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC34621 | IACS-8968 | 2144425-14-7 | >98.00% | |
IACS-8968是IDO和TDO的双抑制剂，其pIC50s值分别为6.43，<5。 | ||||
| GC34622 | IACS-8968 R-enantiomer | 2239305-67-8 | >98.00% | |
IACS-8968(R-enantiomer)是IACS-8968的R型对映异构体。IACS-8968是IDO和TDO的双抑制剂，其pIC50s值分别为6.43，<5。 | ||||
| GC34623 | IACS-8968 S-enantiomer | 2239305-70-3 | >98.00% | |
IACS-8968(S-enantiomer)是IACS-8968的S型对映异构体。IACS-8968是IDO和TDO的双抑制剂，其pIC50s值分别为6.43，<5。 | ||||
| GC34634 | JG-98 | 1456551-16-8 | >98.00% | |
JG-98 is an allosteric inhibitor of Hsp70 that binds tightly to a deep pocket that is conserved in members of the Hsp70 family. JG-98 induces classical apoptosis features, including morphological changes consistent with programmed cell death and positive annexin staining. JG-98 exhibits anticancer activity. | ||||
| GC34705 | PDE2/PDE10-IN-1 | 1426833-08-0 | >99.50% | |
PDE2/PDE10-IN-1是一种磷酸二酯酶PDE2和PDE10抑制剂，IC50分别为29和480nM。 | ||||
| GC34895 | D159687 | 1155877-97-6 | >98.00% | |
D159687是一种选择性PDE4D抑制剂。 | ||||
| GC34939 | UAMC-3203 hydrochloride | 2271358-65-5 | >98.50% | |
A ferroptosis inhibitor | ||||
| GC34980 | (E)-Ferulic acid | 537-98-4 | >99.00% | |
Trans-ferulic acid is a potent activator of AMPKunder high glucose condition. | ||||
| GC34984 | (R)-(-)-Rolipram | 85416-75-7 | >97.00% | |
A PDE4 inhibitor | ||||
| GC35024 | [pTyr5] EGFR 988-993 | 159453-08-4 | - | |
[pTyr5] EGFR (988-993) 来源于表皮生长因子受体(EGFR 988-993)的自磷酸化位点(Tyr992)。[pTyr5] EGFR(988-993)常与催化活性低的蛋白-酪氨酸磷酸1B (PTP1B)结合。 | ||||
| GC35065 | 1-Linoleoyl Glycerol | 2277-28-3 | >98.00% | |
A PAF- AH inhibitor | ||||
| GC35068 | 1-Monomyristin | 589-68-4 | >98.00% | |
A monoacylglycerol | ||||
| GC35143 | 4-O-Methyl honokiol | 68592-15-4 | >99.50% | |
A phenol with diverse biological activities | ||||
| GC35201 | 8-Geranyloxypsoralen | 7437-55-0 | >98.00% | |
8-Geranyloxypsoralen 是从葡萄柚中分离出的一种呋喃香豆素，能作为 P450 3A4 (CYP3A4) 的有效抑制剂，其 IC50 值为 3.93 μM。 | ||||
| GC35236 | Acetylshikonin | 24502-78-1 | >98.00% | |
Acetylshikonin，来源于紫草根，具有抗癌、抗炎作用。Acetylshikonin 是一种非选择性的细胞色素 P450 抑制剂，对所有 P450 亚型抑制的 IC50 值范围为 1.4-4.0 μM。Acetylshikonin 是一种 AChE 抑制剂，具有很强的抗凋亡活性。 | ||||
| GC35250 | Adenosine deaminase | 9026-93-1 | >98.00% | |
腺苷脱氨酶（Adenosine deaminase，ADA）是参与嘌呤代谢途径的关键酶，对腺苷和脱氧腺苷具有不可逆脱氨作用，分别转化为肌苷和脱氧肌苷。 | ||||
| GC35281 | Aleglitazar | 475479-34-6 | >99.00% | |
Aleglitazar(R1439; RO-0728804)是PPAR-α/γ激动剂，IC50分别为2.8 nM/4.6 nM。 | ||||
| GC35298 | Aloe-emodin-8-O-β-D-glucopyranoside | 33037-46-6 | - | |
Aloe-emodin-8-O-β-D-glucopyranoside 是从 Saussrurea lappa 中分离出的化合物，是温和的人类蛋白酪氨酸磷酸酶 1B (hPTP1B) 抑制剂，其 IC50 值为 26.6 μM。 | ||||
| GC35308 | Alpinetin | 36052-37-6 | >98.00% | |
Alpinetin, a composition of Alpinia katsumadai Hayata, has been reported to have a number of biological properties, such as antibacterial, antitumor and other important therapeutic activities. Alpinetin is a flavonoid isolated from Alpinia katsumadai Hayata, activates activates PPAR-γ, with potent anti-inflammatory activity. | ||||
| GC35349 | Angeloylgomisin H | 66056-22-2 | - | |
Angeloylgomisin H 是一种木脂素类化合物，可从五味子 (Schisandra rubriflora) 中提取。Angeloylgomisin H 通过激活 PPAR-γ 来改善胰岛素刺激的葡萄糖摄取潜力。 | ||||
| GC35358 | Ankaflavin | 50980-32-0 | - | |
Ankaflavin 是从Monascus-Fermented 红米中提取得到的，是PPARγ 的激动剂，具有抗炎活性。Ankaflavin 具有选择性的细胞毒性作用，诱导癌细胞死亡。 | ||||
| GC35371 | AP-III-a4 hydrochloride | 2070014-95-6 | - | |
AP-III-a4 hydrochloride是第一个非底物类似物烯醇化酶抑制剂（IC 50 = 0.576μM）。 | ||||
| GC35390 | Aristolochic acid C | 4849-90-5 | >99.50% | |
An alkaloid with anticancer activity | ||||
| GC35398 | Arteannuin B | 50906-56-4 | >98.00% | |
A precursor to artemisinin with diverse biological activities | ||||