Proteases
Proteases(蛋白酶)
Proteases, also known as peptidases or proteolytic enzymes, consists of a large number of enzymes catalyzing the hydrolysis of peptide bonds and subsequently resulting in the degradation of protein substrates into amino acids. Proteases are involved in a wide range of human diseases, including cancer, neurodegenerative disorders, inflammatory diseases and cardiovascular diseases. Thus numerous proteases inhibitors (small molecules and proteins) have been identified to block activity of proteases. Proteases inhibitors can be classified into different types based on the class of proteases they inhibit through two general mechanisms, irreversible “trapping” reactions and reversible tight-binding reactions. Proteases inhibitors have been used as diagnostic or therapeutic agents for the treatment of proteases-related diseases.
- Aminopeptidase(21)
- ACE(75)
- Calpains(11)
- Carboxypeptidase(9)
- Cathepsin(65)
- DPP-4(18)
- Elastase(25)
- Gamma Secretase(50)
- HCV Protease(39)
- HSP(105)
- HIV Integrase(30)
- HIV Protease(35)
- MMP(195)
- NS3/4a protease(4)
- Serine Protease(19)
- Thrombin(47)
- Urokinase(2)
- Cysteine Protease
- Tyrosinases(50)
- Other Proteases(15)
- 15-PGDH(1)
- Acetyl-CoA Carboxylase(14)
- Acyltransferase(64)
- Aldehyde Dehydrogenase (ALDH)(30)
- Aminoacyl-tRNA Synthetase(9)
- ATGL(1)
- Dipeptidyl Peptidase(49)
- Drug Metabolite(513)
- E1/E2/E3 Enzyme(92)
- Endogenous Metabolite(1768)
- FABP(9)
- Farnesyl Transferase(20)
- Glutaminase(17)
- Glutathione Peroxidase(35)
- Isocitrate Dehydrogenase (IDH)(28)
- Lactate Dehydrogenase(19)
- Lipoxygenase(274)
- Mitochondrial Metabolism(260)
- NEDD8-activating Enzyme(6)
- Neprilysin(12)
- PAI-1(14)
- Ser/Thr Protease(49)
- Tryptophan Hydroxylase(12)
- Xanthine Oxidase(18)
- MALT1(10)
- Caspase(117)
- PCSK9(13)
- ADAMTS(1)
- Density Lipoprotein
- TrxR(1)
- DGK(3)
Proteases 相关产品(4079)
- GC72541Docosanoic acid (12,12,13,13-d4)CAS: 1219804-98-4纯度: >99.00%
Docosanoic acid (12,12,13,13-d4)是氘标记的二十二碳烯酸。
- GC72558L-Histidine-13C hydrochloride hydrateCAS: 2483735-43-7纯度: 98.00%
L-Histidine-13C hydrochloride hydrate是13c标记的l -组氨酸盐酸盐水合物。
- GC72559L-Histidine-15N hydrochloride hydrate纯度: >99.00%
L-Histidine-15N hydrochloride hydrate是15n标记的l -组氨酸盐酸盐水合物。
- GC725813-Methyl-L-histidine-d3 hydrochloride纯度: 不显示
3-Methyl-L-histidine-d3 hydrochloride是氘标记的3-甲基- l-组氨酸盐酸。
- GC72585L-Asparagine-13C4,15N2,d3 monohydrateCAS: 2483829-30-5纯度: >99.00%
L-Asparagine-13C4,15N2,d3 monohydrate是氘,13C-和15标记的l -天冬酰胺一水化合物。
- GC72637Hexadecanoate-13C16 potassiumCAS: 1458714-74-3纯度: >98.00%
Hexadecanoate-13C16 potassium是13C标记的十六烷酸钠。
- GC726795-O-MethylembelinCAS: 56005-10-8纯度: >98.00%
5-O-Methylembelin抑制PCSK9、低密度脂蛋白受体诱导降解物(IDLR)和固醇调节元件结合蛋白2(SREBP2)mRNA表达。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC72529 | Palmitoleic acid-13C16 | 2483735-57-3 | 不显示 | |
Palmitoleic acid-13C16是13C标记的棕榈油酸。 | ||||
| GC72532 | Dodecanedioic acid-d20 | 89613-32-1 | >99.00% | |
Dodecanedioic acid-d20是氘标记的十二烷二酸。 | ||||
| GC72533 | Dodecanedioic acid-d4 | 97543-02-7 | 不显示 | |
Dodecanedioic acid-d4是氘标记的十二烷二酸。 | ||||
| GC72537 | 4-Methylcatechol-d6 | 1219804-79-1 | 不显示 | |
4-Methylcatechol-d6是氘标记的4-甲基儿茶酚。 | ||||
| GC72539 | Isovaleric acid-d7 | 1219805-32-9 | 不显示 | |
Isovaleric acid-d7是氘标记的异戊酸。 | ||||
| GC72541 | Docosanoic acid (12,12,13,13-d4) | 1219804-98-4 | >99.00% | |
Docosanoic acid (12,12,13,13-d4)是氘标记的二十二碳烯酸。 | ||||
| GC72546 | 2-Ketoglutaric acid-13C5 | 161096-83-9 | >98.00% | |
2-Ketoglutaric acid-13C5是13C标记的2-酮戊二酸。 | ||||
| GC72547 | 2-Ketoglutaric acid-d6 | 1173021-86-7 | >98.00% | |
2-Ketoglutaric acid-d6是氘标记的2-酮戊二酸。 | ||||
| GC72552 | 1-Hydroxypyrene-d9 | 132603-37-3 | 不显示 | |
1-Hydroxypyrene-d9是氘标记的1-羟基芘。 | ||||
| GC72556 | 3-Phenoxybenzoic acid-13C6 | 1793055-05-6 | 不显示 | |
3-Phenoxybenzoic acid-13C6为13C6标记的3-苯氧苯甲酸。 | ||||
| GC72558 | L-Histidine-13C hydrochloride hydrate | 2483735-43-7 | 98.00% | |
L-Histidine-13C hydrochloride hydrate是13c标记的l -组氨酸盐酸盐水合物。 | ||||
| GC72559 | L-Histidine-15N hydrochloride hydrate | - | >99.00% | |
L-Histidine-15N hydrochloride hydrate是15n标记的l -组氨酸盐酸盐水合物。 | ||||
| GC72563 | Suberic acid-d4 | 19031-57-3 | >99.00% | |
Suberic acid-d4是氘标记的苏比克酸。 | ||||
| GC72568 | Mandelic acid-2,3,4,5,6-d5 | 70838-71-0 | 不显示 | |
Mandelic acid-2,3,4,5,6-d5是氘标记的曼德尔酸。 | ||||
| GC72578 | Triethyl phosphatel-d15 | 135942-11-9 | 不显示 | |
Triethyl phosphatel-d15是氘标记的磷酸三乙基。 | ||||
| GC72581 | 3-Methyl-L-histidine-d3 hydrochloride | - | 不显示 | |
3-Methyl-L-histidine-d3 hydrochloride是氘标记的3-甲基- l-组氨酸盐酸。 | ||||
| GC72585 | L-Asparagine-13C4,15N2,d3 monohydrate | 2483829-30-5 | >99.00% | |
L-Asparagine-13C4,15N2,d3 monohydrate是氘,13C-和15标记的l -天冬酰胺一水化合物。 | ||||
| GC72586 | Adipic acid-d4 | 121311-78-2 | >98.00% | |
Adipic acid-d4是氘标记的己二酸。 | ||||
| GC72587 | D-Ribose-d2 | 478506-32-0 | >98.00% | |
D-Ribose-d2是氘标记的d -核糖。 | ||||
| GC72588 | D-Ribose-d5 | - | >99.00% | |
D-Ribose-d5是氘标记的d -核糖。 | ||||
| GC72589 | D-Ribose-13C-4 | - | >99.00% | |
D-Ribose-13C-4是13C标记的d -核糖。 | ||||
| GC72603 | Glycocyamine-d2 | 1173020-63-7 | >99.00% | |
Glycocyamine-d2是氘标记的糖胺。 | ||||
| GC72637 | Hexadecanoate-13C16 potassium | 1458714-74-3 | >98.00% | |
Hexadecanoate-13C16 potassium是13C标记的十六烷酸钠。 | ||||
| GC72679 | 5-O-Methylembelin | 56005-10-8 | >98.00% | |
5-O-Methylembelin抑制PCSK9、低密度脂蛋白受体诱导降解物(IDLR)和固醇调节元件结合蛋白2(SREBP2)mRNA表达。 | ||||
