Proteases
Proteases(蛋白酶)
Proteases, also known as peptidases or proteolytic enzymes, consists of a large number of enzymes catalyzing the hydrolysis of peptide bonds and subsequently resulting in the degradation of protein substrates into amino acids. Proteases are involved in a wide range of human diseases, including cancer, neurodegenerative disorders, inflammatory diseases and cardiovascular diseases. Thus numerous proteases inhibitors (small molecules and proteins) have been identified to block activity of proteases. Proteases inhibitors can be classified into different types based on the class of proteases they inhibit through two general mechanisms, irreversible “trapping” reactions and reversible tight-binding reactions. Proteases inhibitors have been used as diagnostic or therapeutic agents for the treatment of proteases-related diseases.
- Aminopeptidase(21)
- ACE(75)
- Calpains(11)
- Carboxypeptidase(9)
- Cathepsin(65)
- DPP-4(18)
- Elastase(25)
- Gamma Secretase(50)
- HCV Protease(39)
- HSP(105)
- HIV Integrase(30)
- HIV Protease(35)
- MMP(195)
- NS3/4a protease(4)
- Serine Protease(19)
- Thrombin(47)
- Urokinase(2)
- Cysteine Protease
- Tyrosinases(50)
- Other Proteases(15)
- 15-PGDH(1)
- Acetyl-CoA Carboxylase(14)
- Acyltransferase(64)
- Aldehyde Dehydrogenase (ALDH)(30)
- Aminoacyl-tRNA Synthetase(9)
- ATGL(1)
- Dipeptidyl Peptidase(49)
- Drug Metabolite(513)
- E1/E2/E3 Enzyme(92)
- Endogenous Metabolite(1768)
- FABP(9)
- Farnesyl Transferase(20)
- Glutaminase(17)
- Glutathione Peroxidase(35)
- Isocitrate Dehydrogenase (IDH)(28)
- Lactate Dehydrogenase(19)
- Lipoxygenase(274)
- Mitochondrial Metabolism(260)
- NEDD8-activating Enzyme(6)
- Neprilysin(12)
- PAI-1(14)
- Ser/Thr Protease(49)
- Tryptophan Hydroxylase(12)
- Xanthine Oxidase(18)
- MALT1(10)
- Caspase(117)
- PCSK9(13)
- ADAMTS(1)
- Density Lipoprotein
- TrxR(1)
- DGK(3)
Proteases 相关产品(4079)
- GC718824,12-Dimethoxy-6-(7,8-dihydroxy-7,8-dihydrostyryl)-2-pyroneCAS: 149947-22-8纯度: 不显示
4,12-Dimethoxy-6-(7,8-dihydroxy-7,8-dihydrostyryl)-2-pyrone化合物3是阳蛇素的羟基化微生物代谢物。
- GC71907Aristololactam IIIaCAS: 97399-89-8纯度: 不显示
Aristololactam IIIa对超氧阴离子的产生和弹性蛋白酶的释放具有显著的抑制作用，IC50值分别为0.12和0.20 μg/mL。
- GC71908Deoxynivalenol-3-β-D-glucosideCAS: 131180-21-7纯度: 不显示
Deoxynivalenol-3-β-D-glucoside（DON-3-β-D-葡萄糖苷）是镰刀菌毒素脱氧雪腐镰刀菌烯醇的植物代谢产物。
- GC719854-Hydroxyphenylacetic acid-d6CAS: 100287-06-7纯度: >98.00%
4-Hydroxyphenylacetic acid-d6是氘标记的4-羟基苯乙酸。
- GC72059UDP-3-O-acyl-GlcNAc disodium纯度: 不显示
UDP-3-O-acyl-GlcNAc disodium是一种大肠杆菌代谢产物，参与3-脱氧-D-甘露糖-辛酮糖（KDO）生物合成途径。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC71849 | Hydrocortisone-d3 | 115699-92-8 | >98.00% | |
Hydrocortisone-d3是氘标记的氢化可的松。 | ||||
| GC71850 | Deoxycholic acid-d5 | 52840-14-9 | 不显示 | |
Deoxycholic acid-d5是氘标记的脱氧胆酸。 | ||||
| GC71851 | L-Tryptophan-13C | 115709-68-7 | >99.00% | |
L-Tryptophan-13C是13C标记的L-色氨酸。 | ||||
| GC71852 | L-Tryptophan-13C11 | 202114-65-6 | >99.00% | |
L-Tryptophan-13C11是13C标记的L-色氨酸。 | ||||
| GC71853 | L-Tryptophan-1-13C | 81201-92-5 | 99.00% | |
L-Tryptophan-1-13C是13C标记的L-色氨酸。 | ||||
| GC71854 | L-Tryptophan-d8 | 1233395-93-1 | >98.00% | |
L-Tryptophan-d8是氘标记的L-色氨酸。 | ||||
| GC71855 | L-Threonine-13C4 | 55443-53-3 | >98.00% | |
L-Threonine-13C4是13C标记的L-苏氨酸。 | ||||
| GC71857 | cis-Vitamin K1 | 16033-41-3 | 不显示 | |
cis-Vitamin K1是维生素K的内源性代谢产物。 | ||||
| GC71858 | D-Valine-d8 | 1116448-82-8 | >99.00% | |
D-Valine-d8是氘标记的D-缬氨酸。 | ||||
| GC71863 | Palmitic acid-13C16 sodium | 2483736-17-8 | >98.00% | |
Palmitic acid-13C16 sodium是13C标记的棕榈酸钠。 | ||||
| GC71865 | Palmitic acid-13C2 | 86683-25-2 | 不显示 | |
Palmitic acid-13C2是13C标记的棕榈酸。 | ||||
| GC71882 | 4,12-Dimethoxy-6-(7,8-dihydroxy-7,8-dihydrostyryl)-2-pyrone | 149947-22-8 | 不显示 | |
4,12-Dimethoxy-6-(7,8-dihydroxy-7,8-dihydrostyryl)-2-pyrone化合物3是阳蛇素的羟基化微生物代谢物。 | ||||
| GC71906 | Thymidine-d3 | 74848-84-3 | 不显示 | |
Thymidine-d3是氘标记的胸苷。 | ||||
| GC71907 | Aristololactam IIIa | 97399-89-8 | 不显示 | |
Aristololactam IIIa对超氧阴离子的产生和弹性蛋白酶的释放具有显著的抑制作用，IC50值分别为0.12和0.20 μg/mL。 | ||||
| GC71908 | Deoxynivalenol-3-β-D-glucoside | 131180-21-7 | 不显示 | |
Deoxynivalenol-3-β-D-glucoside（DON-3-β-D-葡萄糖苷）是镰刀菌毒素脱氧雪腐镰刀菌烯醇的植物代谢产物。 | ||||
| GC71917 | Moracin N | 135248-05-4 | >99.00% | |
Moracin N是一种可以从桑叶中分离出来的铁中毒抑制剂。 | ||||
| GC71947 | Acetyl-binankadsurin A | 77174-33-5 | 不显示 | |
Acetyl-binankadsurin A（化合物5）是从长脚南五味子中分离得到的木脂素。 | ||||
| GC71954 | Isocrenatoside | 221895-09-6 | 不显示 | |
Isocrenatoside（化合物6）是环八肽和血管紧张素转换酶（ACE）抑制剂。 | ||||
| GC71980 | β-Caryophyllene-d2 | 2006272-96-2 | >94.00% | |
β-Caryophyllene-d2是氘标记的β-石竹烯。 | ||||
| GC71985 | 4-Hydroxyphenylacetic acid-d6 | 100287-06-7 | >98.00% | |
4-Hydroxyphenylacetic acid-d6是氘标记的4-羟基苯乙酸。 | ||||
| GC72029 | D-Fructose-13C-1 | 117013-19-1 | >98.00% | |
D-Fructose-13C-1是13C标记的D-果糖。 | ||||
| GC72030 | D-Fructose-d | 374089-83-5 | >98.00% | |
D-Fructose-d是氘标记的D-果糖。 | ||||
| GC72059 | UDP-3-O-acyl-GlcNAc disodium | - | 不显示 | |
UDP-3-O-acyl-GlcNAc disodium是一种大肠杆菌代谢产物，参与3-脱氧-D-甘露糖-辛酮糖（KDO）生物合成途径。 | ||||
| GC72060 | 5-Dihydrocortisone | 28423-48-5 | >99.00% | |
5-Dihydrocortisone是含有同分异构体的5-Dihydrocortisone。 | ||||