Proteases
Proteases(蛋白酶)
Proteases, also known as peptidases or proteolytic enzymes, consists of a large number of enzymes catalyzing the hydrolysis of peptide bonds and subsequently resulting in the degradation of protein substrates into amino acids. Proteases are involved in a wide range of human diseases, including cancer, neurodegenerative disorders, inflammatory diseases and cardiovascular diseases. Thus numerous proteases inhibitors (small molecules and proteins) have been identified to block activity of proteases. Proteases inhibitors can be classified into different types based on the class of proteases they inhibit through two general mechanisms, irreversible “trapping” reactions and reversible tight-binding reactions. Proteases inhibitors have been used as diagnostic or therapeutic agents for the treatment of proteases-related diseases.
- Aminopeptidase(21)
- ACE(75)
- Calpains(11)
- Carboxypeptidase(9)
- Cathepsin(65)
- DPP-4(18)
- Elastase(25)
- Gamma Secretase(50)
- HCV Protease(39)
- HSP(105)
- HIV Integrase(30)
- HIV Protease(35)
- MMP(195)
- NS3/4a protease(4)
- Serine Protease(19)
- Thrombin(47)
- Urokinase(2)
- Cysteine Protease
- Tyrosinases(50)
- Other Proteases(15)
- 15-PGDH(1)
- Acetyl-CoA Carboxylase(14)
- Acyltransferase(64)
- Aldehyde Dehydrogenase (ALDH)(30)
- Aminoacyl-tRNA Synthetase(9)
- ATGL(1)
- Dipeptidyl Peptidase(49)
- Drug Metabolite(513)
- E1/E2/E3 Enzyme(92)
- Endogenous Metabolite(1768)
- FABP(9)
- Farnesyl Transferase(20)
- Glutaminase(17)
- Glutathione Peroxidase(35)
- Isocitrate Dehydrogenase (IDH)(28)
- Lactate Dehydrogenase(19)
- Lipoxygenase(274)
- Mitochondrial Metabolism(260)
- NEDD8-activating Enzyme(6)
- Neprilysin(12)
- PAI-1(14)
- Ser/Thr Protease(49)
- Tryptophan Hydroxylase(12)
- Xanthine Oxidase(18)
- MALT1(10)
- Caspase(117)
- PCSK9(13)
- ADAMTS(1)
- Density Lipoprotein
- TrxR(1)
- DGK(3)
Proteases 相关产品(4079)
- GC71806Catechol O-methyltransferase, porcine liverCAS: 9012-25-3纯度: 不显示
Catechol O-methyltransferase, porcine liver（COMT），镁依赖性甲基从S-腺苷甲硫氨酸转移到多巴胺上的羟基，将其转化为3-甲氧基酪胺。
- GC71807FAD-dependent glucose dehydrogenaseCAS: 37250-84-3纯度: 不显示
FAD-dependent glucose dehydrogenase（EC 1.1.5.9），也称为假单胞菌葡萄糖脱氢酶（FAD）或假单胞菌葡糖脱氢酶。
- GC71810β-1,4-Galactosyltransferase, neisseria meningitidesCAS: 9054-94-8纯度: 90.00%
β-1,4-Galactosyltransferase, neisseria meningitides通常用于生化研究。
- GC71811alpha-1,3-N-Acetylgalactosaminyltransferase (Pm1138)CAS: 9067-69-0纯度: 不显示
alpha-1,3-N-Acetylgalactosaminyltransferase (Pm1138) EC 2.4.1.40Pm1138，也即具有糖基转移酶活性的ABO系统转移酶。
- GC71814α-1-3,4 Fucosyltransferase, helicobacter pyloriCAS: 37277-69-3纯度: >90.00%
α-1-3,4 Fucosyltransferase幽门螺杆菌中存在α1,3/4FucT（EC 2.4.1.65）（Hp3/4FT）。
- GC71815α-2,3-Sialyltransferase, pasteurella multocidaCAS: 71124-51-1纯度: 不显示
α-2,3-Sialyltransferase, pasteurella multocida是一种β-半乳糖苷。
- GC71816alpha-1,3-Fucosyltransferase (α1,3FucT)CAS: 37277-69-3纯度: 不显示
alpha-1,3-Fucosyltransferase (α1,3FucT)催化L-岩藻糖部分从鸟苷二磷酸-β-L-岩藻糖GD-Fuc转移到受体糖。
- GC718294-•Hydroxy-•3-•methoxy benzaldehyde-•d3CAS: 74495-74-2纯度: 不显示
4-•Hydroxy-•3-•methoxy benzaldehyde-•d3是氘标记的香草醛。
- GC71844L-Arginine-13C hydrochlorideCAS: 94740-43-9纯度: >99.50%
L-Arginine-13C hydrochloride是13C标记的L-精氨酸盐酸盐。
- GC71846L-Lysine-13C dihydrochlorideCAS: 202190-50-9纯度: >99.00%
L-Lysine-13C dihydrochloride是13C标记的L-赖氨酸二盐酸盐。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC71806 | Catechol O-methyltransferase, porcine liver | 9012-25-3 | 不显示 | |
Catechol O-methyltransferase, porcine liver（COMT），镁依赖性甲基从S-腺苷甲硫氨酸转移到多巴胺上的羟基，将其转化为3-甲氧基酪胺。 | ||||
| GC71807 | FAD-dependent glucose dehydrogenase | 37250-84-3 | 不显示 | |
FAD-dependent glucose dehydrogenase（EC 1.1.5.9），也称为假单胞菌葡萄糖脱氢酶（FAD）或假单胞菌葡糖脱氢酶。 | ||||
| GC71809 | Nucleoside hydrolase (IAGNH) | 9025-44-9 | 不显示 | |
Nucleoside hydrolase (IAGNH)是一种糖苷酶。 | ||||
| GC71810 | β-1,4-Galactosyltransferase, neisseria meningitides | 9054-94-8 | 90.00% | |
β-1,4-Galactosyltransferase, neisseria meningitides通常用于生化研究。 | ||||
| GC71811 | alpha-1,3-N-Acetylgalactosaminyltransferase (Pm1138) | 9067-69-0 | 不显示 | |
alpha-1,3-N-Acetylgalactosaminyltransferase (Pm1138) EC 2.4.1.40Pm1138，也即具有糖基转移酶活性的ABO系统转移酶。 | ||||
| GC71814 | α-1-3,4 Fucosyltransferase, helicobacter pylori | 37277-69-3 | >90.00% | |
α-1-3,4 Fucosyltransferase幽门螺杆菌中存在α1,3/4FucT（EC 2.4.1.65）（Hp3/4FT）。 | ||||
| GC71815 | α-2,3-Sialyltransferase, pasteurella multocida | 71124-51-1 | 不显示 | |
α-2,3-Sialyltransferase, pasteurella multocida是一种β-半乳糖苷。 | ||||
| GC71816 | alpha-1,3-Fucosyltransferase (α1,3FucT) | 37277-69-3 | 不显示 | |
alpha-1,3-Fucosyltransferase (α1,3FucT)催化L-岩藻糖部分从鸟苷二磷酸-β-L-岩藻糖GD-Fuc转移到受体糖。 | ||||
| GC71821 | Endoproteinase Glu-C | 137010-42-5 | 不显示 | |
Endoproteinase Glu-C是一种丝氨酸蛋白酶。 | ||||
| GC71824 | Cytosine-13C2,15N2 | 285978-06-5 | 不显示 | |
Cytosine-13C2,15N2是13C标记和15N标记的胞嘧啶。 | ||||
| GC71827 | Hypoxanthine-d2 | 697807-02-6 | 98.00% | |
Hypoxanthine-d2是氘标记的次黄嘌呤。 | ||||
| GC71828 | Hypoxanthine-15N4 | 77910-30-6 | >98.00% | |
Hypoxanthine-15N4是15N标记的次黄嘌呤。 | ||||
| GC71829 | 4-•Hydroxy-•3-•methoxy benzaldehyde-•d3 | 74495-74-2 | 不显示 | |
4-•Hydroxy-•3-•methoxy benzaldehyde-•d3是氘标记的香草醛。 | ||||
| GC71832 | L-DOPA-d6 | 713140-75-1 | >99.00% | |
L-DOPA-d6是氘标记的L-DOPA。 | ||||
| GC71834 | L-Methionine-d4 | 67866-75-5 | >97.00% | |
L-Methionine-d4是氘标记的L-蛋氨酸。 | ||||
| GC71835 | D-Mannose-13C6 | 287100-74-7 | >98.00% | |
D-Mannose-13C6是一种碳水化合物，在人体代谢中起着重要作用，特别是在特定蛋白质的糖基化中。 | ||||
| GC71836 | Homovanillic acid-13C6,18O | 202468-52-8 | >99.00% | |
Homovanillic acid-13C6,18O是13C标记的高香草酸。 | ||||
| GC71838 | L-Citrulline-d4 | 1217474-00-4 | >98.00% | |
L-Citrulline-d4是氘标记的L-瓜氨酸。 | ||||
| GC71842 | Succinic acid-13C4 | 201595-67-7 | 不显示 | |
Succinic acid-13C4是13C标记的琥珀酸。 | ||||
| GC71843 | Butanedioic acid-13C2 | 79864-95-2 | 不显示 | |
Butanedioic acid-13C2是13C标记的琥珀酸。 | ||||
| GC71844 | L-Arginine-13C hydrochloride | 94740-43-9 | >99.50% | |
L-Arginine-13C hydrochloride是13C标记的L-精氨酸盐酸盐。 | ||||
| GC71846 | L-Lysine-13C dihydrochloride | 202190-50-9 | >99.00% | |
L-Lysine-13C dihydrochloride是13C标记的L-赖氨酸二盐酸盐。 | ||||
| GC71847 | L-Tyrosine-4-13C | 81201-90-3 | >99.00% | |
L-Tyrosine-4-13C是13C标记的L-酪氨酸。 | ||||
| GC71848 | Hydrocortisone-d7 | - | 不显示 | |
Hydrocortisone-d7是氘标记的氢化可的松。 | ||||