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Home >> Signaling Pathways >> Metabolism

Metabolism(代谢)

  1. Cat.No. 产品名称 Information
  2. GC16697 fluoro-Dapagliflozin

    flouro-DAPA

     A potent inhibitor of hSGLT2
  3. GC17112 Uniconazole

    烯效唑,S 3307D,XE 1019D

     A plant growth regulator
  4. GC12546 JP83 A potent, irreversible FAAH inhibitor
  5. GC12262 2-Phenyl-2-(1-piperidinyl)propane

    1-(1-甲基-1-苯基乙基)哌啶

     A selective inhibitor of CYP2B6
  6. GC11125 Sp-Cyclic AMPS (sodium salt)

    Sp-cAMPS

     A cAMP derivative
  7. GC11116 Thioetheramide-PC

    1-Palmitylthio-2-palmitoylamido-1,2-dideoxy-sn-glycero-3-phosphorylcholine

     A competitive, reversible inhibitor of sPLA2
  8. GC14595 MCC-555

    Isaglitazone,Netoglitazone,RWJ 241947

     A structural homolog of rosiglitazone
  9. GC17013 Amidepsine D A diacylglycerol acyltransferase inhibitor
  10. GC11675 Amidepsine A

    FO-2942A

     A diacylglycerol acyltransferase inhibitor
  11. GC15210 PF-622 A selective, potent FAAH inhibitor
  12. GC15833 Norharmane

    去甲哈尔满; Norharman; β-Carboline

     A co-mutagenic heterocyclic amine
  13. GC12400 N-Octadecyl-N'-propyl-sulfamide A potent PPARα activator
  14. GC14411 Apoptozole

    Apoptosis Activator VII

     Apoptozole是一种小分子抑制剂，可靶向HSC70和HSP72，KD值分别为210nM和140nM。
  15. GC11732 GW 590735 A potent and selective agonist of PPARα
  16. GC16072 ML-030

    CID-11757146

     A selective inhibitor of PDE4A
  17. GC11731 4-phenyl-1,2,3-Thiadiazole

    4-苯基-1,2,3-噻重氮,NSC 111906

     Selective inhibitor of CYP2B4 and CYP2E1
  18. GC17293 PHGDH-inactive

    3-Phosphoglycerate Dehydrogenase-inactive

     A negative control for NCT-502 and NCT-503
  19. GC13956 2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide

    2'-(5-chloro-2-nitrophenylthio)-Acetanilide

     An inhibitor of PDE7
  20. GC15056 β-Nicotyrine

    二烯烟碱,α-Nicotyrine,NSC 127943,NSC 407276

     β-Nicotyrine是一种尼古丁的热解产物，可与细胞色素P450 (CYP) isoforms CYP2A6和CYP2A13结合，并能更有效地抑制CYP2A6的活性
  21. GC15547 Inosine-5'-monophosphate (sodium salt hydrate)

    肌苷-5′-磷酸二钠盐,IMP,Inosinic Acid

     A 5’-ribonucleoside
  22. GC11477 Darglitazone

    达格列酮,CP 86,325

     A PPARγ agonist
  23. GC11782 Ophiobolin A

    蛇孢菌素A,Cochliobolin,NSC 114340

     A calmodulin antagonist
  24. GC10796 Eggmanone

    EGM1

     A selective phosphodiesterase 4 inhibitor
  25. GC13836 2,3-dihydrothieno-Thiadiazole Carboxylate

    MTCC

     Selective CYP450 inhibitor
  26. GC10868 6,7-Dimethyltetrahydropterin (hydrochloride) GTP cyclohydrolase I inhibitor
  27. GC10285 N-Arachidonyl Maleimide

    N-花生四烯酸马来酰亚胺

    A potent inhibitor of monoacylglycerol lipase
  28. GC10594 Sodium Fluoride

    氟化钠

     Sodium Fluoride作为氟的另一种形式，经口服后可蓄积于生殖器官，干扰激素调控并激活氧化应激通路，从而导致生殖毒性。
  29. GC12306 Imidazole

    咪唑; 1,3-Diaza-2,4-cyclopentadiene; Glyoxaline

     咪唑是一个平面五元环。
  30. GC12093 Sodium tartrate

    酒石酸钠

     酒石酸钠是一种具有抗氧化活性的 pH 调节剂。
  31. GC16396 Sodium molybdate

    钼酸钠; Molybdate disodium

     钼酸钠（钼酸二钠）是一种有用的钼酸盐来源。
  32. GC15257 Perhexiline (maleate)

    马来酸哌克昔林

     Inhibitor of carnitine palmitoyltransferases
  33. GC11758 4-phenyl-5-methyl-1,2,3-Thiadiazole

    5-甲基-4-苯基-1,2,3-噻二唑,NSC 358739

    CYP2B4 and CYP2E1 inhibitor
  34. GC10462 6-Aminonicotinamide

    6-氨基烟酰胺

     6-Aminonicotinamide是一种有效的烟酰胺抗代谢物，是竞争性 NADP+ 依赖性酶葡萄糖-6-磷酸脱氢酶 (G6PD) 的抑制剂(Ki=0.46μM)。
  35. GC11864 6,7-dihydroxy Bergamottin

    二羟基香柠檬素,6,7-DHB

     A potent CYP3A4 inhibitor
  36. GC12285 Simvastatin (sodium salt)

    辛伐他汀钠盐; Tenivastatin sodium; Simvastatin Impurity A sodium

     An HMG-CoA reductase inhibitor
  37. GC14601 BW 755C Dual 5-LO/COX inhibitor
  38. GC11243 Halopemide

    卤培米特,NSC 354856,R34301

     Inhibitor of phospholipase D1 and D2
  39. GC11969 Adenosine-5'-diphosphate

    二磷酸腺苷,Adenosine Pyrophosphate,ADP,5′-ADP

     Adenosine-5'-diphosphate是 P2Y1、P2Y12、P2Y13 等嘌呤能 P2Y 受体的天然激动剂，可直接结合并触发下游信号级联。
  40. GC12981 OU749 Inhibitor of γ-glutamyl transferase
  41. GC17159 4-(n-nonyl) Benzeneboronic Acid

    4-壬基苯硼酸

     Potent inhibitor of FAAH
  42. GC11806 β-Glycerophosphate (sodium salt hydrate)

    五水β-甘油磷酸钠(二钠五水合物)

    An inhibitor of alkaline phosphatase
  43. GC13470 Rhapontigenin

    丹叶大黄素

     Rhapontigenin（丹叶大黄素）是一种有效的细胞色素P4501A1选择性灭活剂，IC50为0.4μM，对P4501A1的选择性分别是P4501A2和P4501B1的400倍和23倍。
  44. GC15231 Oleoyl Ethyl Amide

    OEtA,N-Ethyloleamide

     An endocannabinoid analog that inhibits FAAH and has analgesic activity
  45. GC12159 HZ52 A reversible inhibitor of 5-lipoxygenase
  46. GC12892 Doxepin (hydrochloride)

    盐酸多塞平

     A tricyclic antidepressant
  47. GC11638 Sulfaphenazole

    磺胺苯吡唑

     Sulfaphenazole是一种磺胺类抗菌药物。它竞争性地抑制细菌二氢叶酸合酶，阻断细菌叶酸合成，从而抑制细菌生长和繁殖。
  48. GC10133 JNJ-42165279

    N-(4-氯-3-吡啶基)-4-[(2,2-二氟-1,3-苯并二恶茂-5-基)甲基]-1-哌嗪甲酰胺

     An irreversible FAAH inhibitor
  49. GC14122 Clorgyline (hydrochloride)

    盐酸氯吉林

     Clorgyline (hydrochloride)是一种不可逆、强效和选择性单胺氧化酶（MAO）A 抑制剂，对MAO-A和MAO-B的Ki值分别为0.054和58μM，IC50值分别为 0.0012和1.9μM。
  50. GC11741 ML-265

    CID-44246499,NCGC00186528,TEPP-46

     ML-265 被广泛用作公认的 PKM2（丙酮酸激酶肌肉亚型 2）激活剂 ML-265 激活 PKM2 在生物化学（AC50 = 92 nM）和基于细胞的测定中对 PKM1（丙酮酸激酶肌肉亚型 1）、PKL 和 PKR 具有高选择性。
  51. GC10850 ML-095 (hydrochloride)

    CID-25067483

     A PLAP inhibitor

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