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Home >> Signaling Pathways >> Metabolism

Metabolism(代谢)

Cat.No. 产品名称 Information
GC18270 22(S)-hydroxy Cholesterol
22(S)-羟基胆固醇,22β-hydroxy Cholesterol
A synthetic oxysterol and LXR modulator
GC18258 CpdA
乙酸-4-[1-氯-2-(甲氨基)乙基]苯酯盐酸盐
A non-steroidal selective glucocorticoid receptor modulator
GC18239 TPI-1
Tyrosine Phosphatase Inhibitor 1
TPI-1（酪氨酸磷酸酶抑制剂1）是一种SHP-1抑制剂（IC₅₀ = 40nM），可用于研究黑色素瘤。
GC18230 ethyl 2,5-Dihydroxybenzoate
二羟基苯甲酸乙酯
A dual modulator of bone cell differentiation
GC18219 6-hydroxy Warfarin
3-(Α-丙酮基苄基)-4,6-二羟基香豆素
A phase I metabolite of (+)-warfarin
GC18214 AM2394 A glucokinase activator
GC18209 4-Nitrophenyl β-D-Cellotetraoside
P-硝基苯基B-D-纤维四糖苷
A small molecule cellulose mimic
GC18205 3,5-Diiodothyroacetic Acid
4-(4-羟基苯氧基)-3,5-二碘-苯基-乙酸
A thyroid hormone derivative
GC18194 4-Epidoxycycline
强力霉素
A metabolite of doxycycline
GC18174 BIA 10-2474
3-(1-(环己基(甲基氨基甲酰基)-1H-咪唑-4-基)吡啶1-氧化物
An inhibitor of FAAH
GC18170 ML-346 An activator of the heat shock response
GC11912 PF-04929113 (SNX-5422)
SNX-5422
A prodrug for an Hsp90 inhibitor
GC13414 AT13387
AT13387,Onalespib
AT13387是一种小分子非安沙霉素类HSP90（热休克蛋白90）抑制剂，其作用机制是通过靶向AKT和ERK信号通路。
GC18151 Elafibranor (GFT505)
GFT505
An agonist of PPARα and PPARδ
GC10828 N,N'-Dicyclohexylurea
N,N-二环己脲,DCU,NSC 17013
A selective sEH inhibitor
GC13519 Navoximod
GDC-0919; NLG-?919
Navoximod (GDC-0919; NLG-919) 是一种有效的 IDO（吲哚胺-(2,3)-双加氧酶）通路抑制剂，Ki/EC50 为 7 nM/75 nM。
GC10136 Tienilic Acid
替宁酸,Ticrynafen; ANP 3624
Suicide substrate of CYP 2C9
GC13963 Oleyl Trifluoromethyl Ketone
Heptadecyl Trifluoromethyl Ketone,OTK
An analog of oleic acid
GC13319 5,8,11-Eicosatriynoic Acid
5,8,11-十二烯酸,5,8,11-ETI
A nonselective inhibitor of lipoxygenases
GC16333 Cycloguanil (hydrochloride)
环氯胍盐酸盐
The active metabolite of proguanil
GC11520 ST638
Α-氰基-(3-乙氧基-4-羟基-5-苯基硫代甲基)肉桂酰胺
Tyrosine kinase inhibitor
GC15909 RB394 A dual modulator of sEH and PPARγ
GC14521 ONO-RS-082 A PLA₂ inhibitor
GC12031 Monoacylglycerol Lipase Inhibitor 21
MAGL Inhibitor 21,MGL Inhibitor 21
A reversible blocker of 2-AG hydrolysis
GC12755 trans-AUCB
反式AUCB,t-AUCB
A potent, orally bioavailable sEH inhibitor
GC16488 SR 2595 An inverse agonist of PPARγ
GC15085 G3335
G3335
A PPARγ antagonist III
GC14232 SR 1824 A non-agonist PPARγ ligand
GC16860 NCT-502 A PHGDH inhibitor
GC10190 DG-172 (hydrochloride) An orally available PPARβ/δ inverse agonist
GC13262 A-771726
特立氟胺; A77 1726
An active metabolite of leflunomide
GC14531 Glycerophospho-N-Oleoyl Ethanolamine Precursor of oleoyl ethanolamide
GC13063 N-Benzylpalmitamide
N-苄基棕榈酰胺,N-Benzylhexadecanamide
A long-chain fatty acid amide
GC15244 Thienyldecyl Isothiocyanate An antiproliferative isothiocyanate
GC15387 TPPU TPPU是一种可溶性环氧化物水解酶(sEH)抑制剂，对猴和人sEH的IC50值分别为37和3.7 nM。
GC10645 MJ33 (lithium salt)
An inhibitor of the PLA₂ activity of Prdx6
GC10869 HA-155
Autotaxin Inhibitor IV
A selective autotaxin inhibitor
GC11540 HET0016
N-hydroxy-N'-(4-n-butyl-2-methylphenyl)Formamidine
HET0016 是一种高选择性的20-羟基花生四烯酸（20-HETE）合成酶抑制剂，对重组CYP4A1、CYP4A2和CYP4A3催化20-HETE合成作用的IC₅₀值分别为17.7nM, 12.1nM和20.6nM。
GC10762 4β-hydroxy Cholesterol
4Β-羟基胆固醇
An oxysterol
GC12289 3-Thiatetradecanoic Acid
3-TDA
An analog of myristic acid
GC12760 LT175 A dual PPARα/γ ligand
GC14618 PPOH Selective inhibitor of epoxygenation reactions catalyzed by CYP4A2 and CYP4A3
GC10778 DDMS
Dibromo-dodecenyl-methylsulfimide
A potent inhibitor of 20-HETE synthesis
GC17190 galacto-Dapagliflozin A potent inhibitor of hSGLT2
GC13275 Ibudilast
异丁司特; KC-404; AV-411; MN-166
An inhibitor of PDE4
GC13953 Methyl α-Linolenyl Fluorophosphonate
MLnFP
A phospholipase inhibitor
GC18141 EA4 An inhibitor of PLA₂ from red blood cells
GC18061 Fusaric Acid
萎蔫酸
镰刀菌酸是一种由镰刀菌产生的真菌毒素，对动植物具有多种毒理作用。
GC16046 Piriprost (potassium salt)
U-60257B
A novel 5-lipoxygenase inhibitor
GC16301 Cetaben
西他苯
A non-fibrate hypolipidemic drug