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Home >> Signaling Pathways >> Metabolism

Metabolism(代谢)

Cat.No. 产品名称 Information
GC18783 13,14-dihydro-15-keto Prostaglandin E1
13,14-二氢-15-酮-前列腺素E1
An inactive metabolite of PGE₁
GC18780 Pladienolide B
普拉地内酯B

An inhibitor of splicing factor SF3b
GC18774 16,16-dimethyl Prostaglandin F2α
16,16dimethyl PGF2α
A stable PGF_2α analog
GC18771 Resveratrol-4'-O-D-Glucuronide
trans-R4'G
A phase II metabolite of trans-resveratrol
GC18768 Prostaglandin E1 ethyl ester
前列腺素EP杂质I
An esterified form of PGE₁
GC18762 Remogliflozin A
Remogliflozin A
A potent inhibitor of SGLT2
GC18718 bpV(pic) (potassium hydrate)
Bisperoxovanadium(pic)
A PTEN inhibitor
GC18706 SR 9186
ML368
A selective inhibitor of CYP3A4
GC18705 ML-210
DPI10
ML-210是一种前体药物，能够选择性共价抑制GPX4，EC₅₀值为30nM。
GC18702 Propiverine N-oxide (hydrochloride) An active propiverine metabolite
GC18698 CAY10665 A stable bioisostere of the antiarrhythmic 17,18-EET
GC18691 CAY10594 CAY10594 是一种有效的磷脂酶 D2 (PLD2) 抑制剂（体外 IC50 为 140 nm，细胞内为 110 nm）。
GC18677 YMU1 A thymidylate kinase inhibitor
GC18654 8-hydroxy Loxapine
8-OH Loxapine
A loxapine metabolite
GC18632 6-hydroxy Bexarotene
6-羟基蓓萨罗丁
An oxidative metabolite of bexarotene
GC18622 (2'S)-Nicotine-1-oxide
(2'S)-尼古丁氧化物
A nicotine metabolite
GC18609 1-Deoxysphinganine (m18:0)
ES-285
An atypical sphingolipid
GC18596 (±)-2-propyl-4-Pentenoic Acid
2-丙基-4-五烯酸,2-Allylpentanoic Acid, 4-ene VPA
A metabolite of valproic acid
GC18582 5'-hydroxy Meloxicam
5'-羟基美洛昔康
A metabolite of meloxicam
GC18575 2-hydroxy Tricosanoic Acid methyl ester
2-羟基二十三烷酸甲酯
A hydroxy fatty acid methyl ester
GC18569 Propofol β-D-Glucuronide
2,6-二异丙基Β-D-吡喃葡萄糖酸
Propofol β-D-Glucuronide是丙泊酚的代谢产物，被广泛用作鉴定动物体内丙泊酚代谢状态的标志物。
GC18559 Lysophosphatidylethanolamines (egg)
溶血磷脂酰乙醇胺(鸡蛋)
A mixture of lysophosphatidylethanolamines isolated from egg
GC18558 CAY10566 CAY10566是一种选择性硬脂酰辅酶A去饱和酶1（SCD1）抑制剂（小鼠：IC₅₀=4.5nM；人：IC₅₀=4.5nM）。
GC18542 5,6-dihydro-5-Fluorouracil
5-氟二氢嘧啶-2,4-二酮
A metabolite of 5-FU
GC18539 4-Hydroxyretinoic acid (4-HRA)
维甲酸杂质
4-Hydroxyretinoic acid (4-HRA)是一种天然存在的，由全反式视黄酸（ATRA）经细胞色素P450酶代谢生成的主要代谢产物。
GC18532 Skyrin
穗花衫双黄酮,Endothianin，Rhodophyscin
A fungal metabolite that blocks glucagon signaling
GC18527 4'-hydroxy Flurbiprofen
4-羟基氟吡洛芬
A major active metabolite of flurbiprofen
GC18507 NSC 617145 NSC 617145是一种靶向Werner综合征解旋酶（WRN）的抑制剂，IC₅₀值为230nM。
GC18498 Cathepsin L Inhibitor (Z-FY-CHO)
SB 412515; Z-FY-CHO
Cathepsin L Inhibitor (Z-FY-CHO)是一种能够特异性抑制Cathepsin L活性的化合物（Ki=0.185nM），用于研究Cathepsin L在细胞内溶酶体功能和蛋白质降解过程中的作用。
GC18496 Leelamine (hydrochloride)
脱氢松香胺盐酸盐
An inhibitor of pyruvate dehydrogenase kinase
GC18490 2α-Mannobiose
2-O-(Α-D-吡喃甘露糖基)-D-吡喃甘露糖
A disaccharide
GC18482 all-trans-5,6-epoxy Retinoic Acid
5,6-epoxy-atRA, 5,6-epoxy RA
An agonist of RAR isoforms
GC18471 DG-051 An LTA₄ hydrolase inhibitor
GC18469 Galactosylcerebrosides (bovine)
半乳糖苷神经酰胺
A sphingolipid
GC18466 5,6-epoxy-13-cis Retinoic Acid
异维A酸EP杂质G
A metabolite of 13-cis retinoic acid
GC18462 3-Formylsalicylic Acid
3-醛基水杨酸
An inhibitor of estrone sulfatase
GC18460 Roquefortine C
异烟棒曲霉素 C
A mycotoxin
GC18455 Digoxigenin Monodigitoxoside
地高辛杂质D
A Na⁺/K⁺-ATPase inhibitor
GC18452 3,4-Dichloroisocoumarin
3,4-DCI

A serine protease inhibitor
GC18439 Doxorubicinone
阿霉酮,Adriamycin aglycone; Adriamycinone
A metabolite of doxorubicin
GC18425 4-hydroxy Atorvastatin lactone
P-羟基阿伐他汀内酯
A metabolite of atorvastatin
GC18417 4-hydroxy Xylazine
4-羟基塞拉嗪
A xylazine metabolite
GC18372 15(S)-15-methyl Prostaglandin F2α methyl ester
15(S)-15-甲基前列腺素
A methyl ester derivative of a potent uterine stimulant and abortifacient
GC18335 6β-hydroxy Dexamethasone
6-羟基地塞米松
A metabolite of dexamethasone
GC18333 Equilenin
马萘雌甾酮
An equine estrogen
GC18313 BAR501 Impurity A GP-BAR1 agonist
GC18305 CAY10650 CAY10650是一种高效的细胞质磷脂酶A2α（cPLA2α）抑制剂，IC₅₀值为12nM。
GC18286 (R)-Mephenytoin
美芬妥英,(-)-Mephenytoin
An enantiomer of mephenytoin
GC18284 7-Methyluric Acid
7-甲基-2,6,8-三羟基嘌呤
A methylated purine
GC18271 Polmacoxib
帕马考昔,CG100649
An inhibitor of COX-2 and carbonic anhydrase