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Home >> Signaling Pathways >> Metabolism

Metabolism(代谢)

  1. Cat.No. 产品名称 Information
  2. GC15943 NCT-503 NCT-503 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂，IC50 为 2.5 μM用 NCT-503 处理三种 PHGDH 非依赖性细胞系和五种 PHGDH 依赖性细胞系表明，NCT-503 对 PHGDH 依赖性细胞系的 EC50 值为 8-16 μM，并且对其他 PHGDH 非依赖性细胞无毒性 行。
  3. GC13276 Oleyloxyethyl Phosphorylcholine

    磷酰胆碱

    A PLA2 inhibitor
  4. GC16770 Arachidonic Acid Leelamide A novel fatty acid amide
  5. GC16438 L-Histidinol (hydrochloride)

    L-组氨醇二盐酸盐,(S)-Histidinol

     An intermediate in L-histidine biosynthesis
  6. GC12829 5-hydroxy Tryptophol

    5-羟基色醇

     A metabolite of tryptophan
  7. GC15286 Dimethyl DL-Glutamate (hydrochloride)

    DL-谷氨酸二甲酯盐酸盐,Glutamic Acid dimethyl ester,Dimethyl 2-aminopentanedioate

     A cell-permeant glutamate derivative
  8. GC13379 1-Naphthyl 3,5-dinitrobenzoate

    1-(3,5-Dinitrobenzoyloxy)naphthalene,1-Naphthalonol 3,5-dinitrobenzoate

     A dual inhibitor of 5-LO and mPGES-1
  9. GC15209 WWL123 A selective inhibitor of ABHD6
  10. GC12150 ML-211 A dual inhibitor of lysophospholipase 1 and 2
  11. GC10331 Ebselen

    依布硒; SPI-1005; PZ-51; CCG-39161

     Ebselen一种具有谷胱甘肽过氧化物酶样活性的硒代有机化合物，是一种抗炎和抗氧化剂。Ebselen是肌醇单磷酸酶（IMPase）的抑制剂，IC50为1.5μM。
  12. GC14954 L-Canaline

    6-硝基-2-氨苯酚-4-磺酸

     A natural inhibitor of aminotransferases
  13. GC16423 Monoacetylphloroglucinol

    2,4,6-三羟基苯乙酮; 2,4,6-trihydroxyacetophenone; 1-(2,4,6-Trihydroxyphenyl)ethanone

     单乙酰间苯三酚（2,4,6-三羟基苯乙酮）是从姜黄中提取的苯乙酮糖苷的苷元部分，具有降低胆固醇的活性。
  14. GC14246 Muraglitazar

    莫格他唑 ,BMS-298585

     A PPARα and PPARγ dual agonist
  15. GC16824 Pargyline (hydrochloride)

    优降宁盐酸盐；盐酸帕吉林；巴吉林盐酸盐

     An irreversible MAO inhibitor
  16. GC14591 Hemin chloride

    氯化血红素; Hemin chloride

     氯化血红素是血红素加氧酶(HO)-1的底物，可诱导多种细胞表达HO-1，发挥抗氧化和抗炎作用。
  17. GC13751 (3S,5S)-Atorvastatin (sodium salt)

    阿托伐他汀EP杂质C

     An enantiomer of atorvastatin
  18. GC13351 VU0359595

    CID-53361951,ML-270

     A selective PLD1 inhibitor
  19. GC11021 Bromoenol lactone

    (6E)-Bromoenol lactone

     A selective, potent, irreversible inhibitor of iPLA2
  20. GC12043 CUDA A potent inhibitor of soluble epoxide hydrolase
  21. GC17354 SW203668 An irreversible inhibitor of stearoyl-CoA desaturase
  22. GC16259 SKF 525A (hydrochloride)

    盐酸丙基解痉素,RP 5171|U 5446

     A nonspecific CYP450 inhibitor
  23. GC15995 BMS 687453 A potent PPARα agonist
  24. GC13776 Piericidin A

    粉蝶霉素A,AR 054, Shaoguanmycin B, SN 198E

     Piericidin A是一种天然的线粒体NADH-泛醌氧化还原酶（复合物I）抑制剂。
  25. GC13763 KT203

    ML-296

     A potent inhibitor of ABHD6
  26. GC16756 KT182 A potent inhibitor of ABHD6
  27. GC16849 MBCQ An inhibitor of PDE5
  28. GC12204 STK393606 A selective inhibitor of 15-PGDH
  29. GC11155 Omeprazole sulfone

    奥美拉唑杂质A,Omeprazole sulfone; Omeprazole sulphone

     The major metabolite of omeprazole
  30. GC11916 GQ-16 A PPARγ partial agonist
  31. GC14486 (S)-Mephenytoin

    甲秦皮素,(S)-5-Ethyl-3-methyl-5-phenylhydantoin

     S-Mephenytoin (5-phenyl-5-ethyl-N-methylhydantoin) 是一种抗惊厥药，通过 N-去甲基化和 4-羟基化（芳环）代谢。
  32. GC12912 BCATc Inhibitor 2

    Cytosolic Branched-Chain Amino Acid Transferase Inhibitor 2

     A selective BCATc inhibitor
  33. GC10821 11-keto-β-Boswellic Acid

    11-酮基-BETA-乳香酸,11-oxo-β-Boswellic acid,KBA

     A 5-LO inhibitor
  34. GC10565 7-hydroxycoumarinyl Arachidonate

    Umbelliferyl Arachidonate

    A substrate for cPLA2
  35. GC16350 Actinonin

    放线酰胺素,(-)-Actinonin,Ro 06-1467

     Actinonin是一种肽模拟抗生素，能够抑制enkephalin-aminopeptidase、enkephalinase A和 dipeptidylaminopeptidase，IC50值分别为0.39μM、5.6μM和1.1μM。
  36. GC10430 Migalastat (GR181413A) hydrochloride

    脱氧半乳糖野生霉素盐酸盐,GR181413A

     Migalastat (GR181413A) hydrochloride是一种口服的α-半乳糖苷酶A竞争性抑制剂，IC50值为0.04µM。
  37. GC12595 DL-α-Difluoromethylornithine (hydrochloride hydrate)

    依氟鸟氨酸盐酸盐一水合物,DFMO,Eflornithine

    An irreversible inhibitor of ornithine decarboxylase
  38. GC10859 Amino Tadalafil

    氨基他达拉非

     An analog of tadalafil
  39. GC10223 CCT018159 An Hsp90 inhibitor
  40. GC15876 IDO-IN-1

    4-氨基-N-(3-溴-4-氟苯基)-N'-羟基-1,2,5-恶二唑-3-甲脒

     A potent IDO inhibitor
  41. GC17780 FTase Inhibitor II

    Farnesyltransferase Inhibitor II,FTI-II

     Ftase inhibitor
  42. GC14282 AKBA (3-acetyl-11-keto-β-Boswellic Acid)

    11-羰基-Β-乙酰乳香酸,3-O-acetyl-11-keto-β-Boswellic acid,AKBA

     AKBA (3-acetyl-11-keto-β-Boswellic Acid)是一种五环三萜酸，能够有效地非竞争性地抑制5-脂氧合酶（5-lipoxygenase, 5-LOX），具有抗炎、抗肿瘤、神经保护等多种生物活性。
  43. GC12493 Desfuroylceftiofur

    去呋喃甲酰基头孢噻呋

    An active metabolite of ceftiofur
  44. GC10533 7,8-dihydro-L-Biopterin

    7,8-二氢生物蝶呤

     A precursor in the synthesis of BH4
  45. GC12624 3,4-DAA A synthetic analog of a tryptophan metabolite
  46. GC15601 AG-120

    艾伏尼布,AG-120

     AG-120 (Ivosidenib)是一种突变型异柠檬酸脱氢酶1（mIDH1）抑制剂。
  47. GC13147 AG-221 (Enasidenib)

    恩西地平; AG-221

     An inhibitor of mutant IDH2
  48. GC17003 Benzenesulfonamide

    苯磺酰胺

     carbonic anhydrase inhibitor
  49. GC12962 Isatin

    靛红,Indoline-2,3-dione

     Isatin (Indoline-2,3-dione) 是一种有效的单胺氧化酶 (MAO) 抑制剂，IC50 为 3 μM。
  50. GC16517 Eugenol

    丁香酚

     丁香酚是一种存在于丁香中的精油，具有抗菌、驱虫和抗氧化活性。
  51. GC10042 Vitamin E

    天然维生素E

     脂溶性维生素

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