Signaling Pathways

KAT8 inhibitor 19 is an inhibitor of lysine acetyltransferase 8 (KAT8; IC50 = 12.1 µM).

Ferroptosis inducer 24 is an inducer of ferroptosis.

7-PPD-Q is an oxidized derivative of the tire antiozonant and a substituted p-phenylenediamine 7-PPD.

Semaglutide is an agonist of glucagon-like peptide 1 receptor (GLP-1R; EC50 = 6.2 pM in a reporter assay using BHK cells expressing the human receptor).

OPPD-Q is a p-phenylenediamine-quinone (PPD-Q) and an oxidized derivative of the aromatic amine antioxidant OPPD .

Verrucarin H is a macrocyclic trichothecene mycotoxin that has been found in M. verrucaria.

ARN25062 is a derivative of ARN22089, an inhibitor of the protein-protein interaction between Cdc42 and p21-activated kinase (PAK).

Ebio1 is an activator of the voltage-gated potassium channel Kv7.2.

Ferrous trisglycinate is an iron amino acid chelate.

Perfluoropropanesulfonic acid is a perfluoroalkyl substance (PFAS).

Akt-I-1 is an inhibitor of Akt1 (IC50 = 4.6 µM).

2-(Morpholin-4-yl)ethane-1-sulfonamide is a byproduct in the synthesis of diazo compounds.

N-Methylnuciferine is an aporphine alkaloid that has been found in A. cherimola and has diverse biological activities.

8(Z),11(Z),14(Z)-Heptadecatrienal is a polyunsaturated fatty aldehyde.

BDW-OH is an active metabolite of the STING agonist and prodrug BDW568 .

Alborixin is an ionophore originally isolated from S. albus that has diverse biological activities.

NSC 44625 is an inhibitor of carbonic anhydrase II (CAII; Ki = 63 nM for the human enzyme).

m-isobutyl Ibuprofen is a potential impurity in commercial preparations of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor ibuprofen.

MRSA antibiotic 1 is an antibiotic.

IPPD-Q是N,N'-取代对苯二胺类化合物（PPD）的氧化产物，消耗二硫苏糖醇（DTT）的氧化潜势值为0.93μM min –1 μM –1 。

CPPD-Q是一种抗氧化剂CPPD的氧化衍生物，具有抑菌和杀虫作用。

Artepillin C is a prenylated cinnamic acid that has been found in B. grisebachii and has diverse biological activities.

4-Acetamido antipyrine (4-AAAP) is an active metabolite of the non-opioid analgesic and antipyretic prodrug metamizole .

Loxoprofen-SRS is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 0.5 and 0.39 for recombinant human COX-1 and COX-2, respectively) and an active metabolite of the prodrug loxoprofen .