BDW-OH is an active metabolite of the STING agonist and prodrug BDW568 .[1],[2]
References:
[1].Zhao, J., Tang, Z., Selvaraju, M., et al.Cellular target deconvolution of small molecules using a selection-based genetic screening platformACS Cent. Sci.8(10)1424-1434(2022).
[2].Tang, Z., Zhoa, J., Li, Y., et al.Structural evaluations of a selective human STINGA230 agonist and its use in macrophage immunotherapiesACS Med. Chem. Lett.15(5)653-658(2024).
















