GlpBio

Metabolism

Metabolism(代谢)

研究方向

Metabolism 相关产品(3072)

  • GC25389 structure
    GC25389Ethyl potassium malonate
    CAS: 6148-64-7

    Ethyl potassium malonate (Potassium 3-ethoxy-3-oxopropanoate) is used as a competitive inhibitor of the enzyme succinate dehydrogenase. It acts as a precursor to produce (trimethylsilyl)ethyl malonate, which is utilized to prepare beta-ketoesters by acylation and serves as an intermediate for the preparation of ethyl tert-butyl malonate.

  • GC25411 structure
    GC25411Fasnall
    CAS: 929978-58-5

    Fasnall, a thiophenopyrimidine, is a selective fatty acid synthase (FASN) inhibitor that shows potent anti-tumor activity.

  • GC26053 structure
    GC26053WAY-297848
    CAS: 404360-27-6

    WAY-297848 is a novel glucokinase activator with potential use as a drug for the prevention or treatment of hyperglycemia, diabetes, obesity, dyslipidemia, metabolic syndrome, etc.

  • GC26184 structure
    GC26184Kynurenic acid-d5
    CAS: 350820-13-2
    纯度: >98.00%

    Kynurenic acid-d 5 是 Kynurenic acid 的氘代物。

  • GC26242 structure
    GC26242Alexa Fluor 594 labeled Concanavalin A
    CAS: 11028-71-0
    纯度: >98.00% / >95.00%

    刀豆蛋白A (Concanavalin ACon A) ，来源于Canavalia ensiformis洋豆 (刀豆)，是一种凝集素蛋白 (Mw 104kDa) 。

  • GC26265 structure
    GC26265α-Hydroxyglutaric acid disodium
    CAS: 40951-21-1
    纯度: ≥98.00%

    α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium 是戊二酸的 α-羟基酸形式。

  • GC26431 structure
    GC26431Pentacosafluorotridecanoic Acid
    CAS: 72629-94-8
    纯度: >97.00%

    Perfluorotridecanoic Acid (Perfluorinated Compound (PFC)) is a perfluorinated alkyl acid (PFAA) and a possible organic pollutant.

  • GC30039 structure
    GC30039FIN56
    CAS: 1083162-61-1
    纯度: >98.00%

    FIN56 是一种新型的铁死亡诱导剂，它通过增加 GPX4 的降解来触发铁死亡 。

  • GC30067 structure
    GC30067Butylhydroxyanisole (Butylated hydroxyanisole)
    CAS: 25013-16-5
    纯度: >99.00%

    丁基羟基茴香醚（Butylated hydroxyanisole）（Butylated hydroxyanisole）是一种抗氧化剂，用作食品添加剂防腐剂。

  • GC30180 structure
    GC30180ST271
    CAS: 106392-48-7
    纯度: >98.50%

    ST271 is a tyrphostin-like protein tyrosine kinase (PTK) inhibitor which inhibits phospholipase D (PLD) activity.

  • GC30366 structure
    GC30366FAAH-IN-2
    CAS: 184475-71-6
    纯度: >99.40%

    FAAH-IN-2是摘自专利WO/2008/100977A2中的FAAH抑制剂。

  • GC30377 structure
    GC30377o-Dianisidine dihydrochloride (3,3'-Dimethoxybenzidine dihydrochloride)
    CAS: 20325-40-0
    纯度: >99.00%

    o-Dianisidine盐酸盐是一个比色过氧化物酶底物，适用于ELISA。

  • GC30379 structure
    GC30379Saroglitazar
    CAS: 495399-09-2
    纯度: >98.00%

    A PPARα and PPARγ dual agonist

  • GC30390 structure
    GC30390Autotaxin modulator 1
    CAS: 1548743-69-6
    纯度: >98.50%

    Autotaxinmodulator1是出自专利WO2014018881A1中的新型Autotaxin调节剂。

  • GC30424 structure
    GC30424(-)-Cephaeline dihydrochloride (NSC 32944)
    CAS: 5853-29-2
    纯度: >99.50%

    (-)-Cephaeline dihydrochloride (NSC 32944) 是一种选择性 CYP2D6 抑制剂，IC50 为 121 μM.

  • GC30437 structure
    GC30437ER21355
    CAS: 150452-18-9

    ER21355是一种磷酸二酯酶5(phosphodiesterase5)的抑制剂，用于治疗前列腺疾病。

  • GC30459 structure
    GC30459Senecionine (Senecionan-11,16-dione, 12-hydroxy-)
    CAS: 130-01-8
    纯度: >99.00%

    A pyrrolizidine alkaloid with hepatotoxic properties

  • GC30462 structure
    GC30462Pparδ agonist 1
    CAS: 1902161-12-9

    Pparδagonist1是PPAR-δ的激动剂，EC50值为5.06nM，可用于研究与PPAR-δ相关的疾病，例如:线粒体疾病、肌肉疾病、血管疾病、脱髓鞘疾病和代谢疾病。

  • GC30464 structure
    GC30464Ecopladib (PLA 725)
    CAS: 381683-92-7

    Ecopladib (PLA 725) 是细胞溶质磷脂酶 A2α 的亚微摩尔抑制剂； (cPLA2α)，在 GLU 胶束和大鼠全血试验中，IC50 分别为 0.15 μM 和 0.11 μM。

  • GC30479 structure
    GC30479Dihydromethysticin ((+)-Dihydromethysticin)
    CAS: 19902-91-1
    纯度: >98.50%

    A kavalactone with diverse biological activities

  • GC30512 structure
    GC30512Vatiquinone (EPI-743)
    CAS: 1213269-98-7
    纯度: >98.00%

    A metabolite of α-tocotrienol with antioxidant and ferroptosis inhibitory activity

  • GC30561 structure
    GC305612-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide
    CAS: 137089-36-2

    2-(E-2-decenoylamino)ethyl2-(cyclohexylethyl)sulfide是一种由压力诱发的溃疡和低毒性抑制剂，可以在压力引起的溃疡大鼠中，维持磷脂酶A2(phospholipaseA2)和前列腺素E2(prostaglandinE2)的含量水平。

  • GC30610 structure
    GC30610LY 178002
    CAS: 107889-32-7

    LY178002是一种有效的5-lipoxygenase，phospholipaseA2抑制剂，对5-lipoxygenase的IC50值为0.6μM，能够抑制人多形核白细胞产生LTB4，同时可相对较弱地抑制cyclooxygenase的活性。

  • GC30657 structure
    GC30657PDE IV-IN-1
    CAS: 225100-12-9

    PDEIV-IN-1是一种有效的phosphodiesteraseIV抑制剂，可用于哮喘，慢性阻塞性肺病和其他炎症性疾病的研究。