Metabolism(代谢)

Cat.No. 产品名称 Information

GC46561 3,4-Di-O-acetyl-L-fucal

2,6-脱水-1,5-二脱氧-L-阿拉伯-己-5-烯糖二乙酸酯

A glycal precursor

GC46540 2'-Deoxyadenosine-5'-triphosphate (sodium salt hydrate) A purine nucleotide

GC46539 2-Chloroadenine

2-氯-6-氨基嘌呤

A heterocyclic building block

GC46525 20-HETE-d6

20-Hydroxyarachidonic acid-d6; 20-Hydroxyeicosatetraenoic acid-d6

An internal standard for the quantification of 20-HETE

GC46509 2,3,4,5-Tetrachlorophenol

2,3,4,5-四氯苯酚

A metabolite of γ-lindane

GC46508 2',2'-Difluoro-2'-deoxyuridine

2'-脱氧-2',2'-二氟尿嘧啶核苷

An active metabolite of gemcitabine

GC46494 1-Stearoyl-2-Arachidonoyl-d11-sn-glycero-3-PC

18:0/20:4-d11-PC, PC(18:0/20:4-d11), SAPC-d11, 1-Stearoyl-2-Arachidonoyl-d11-sn-glycero-3-Phosphatidylcholine, 1-Stearoyl-2-Arachidonoyl-d11-sn-glycero-3-Phosphocholine

A neuropeptide with diverse biological activities

GC46477 1-Amino-1-deoxy-D-fructose (hydrochloride)

D-异葡萄糖胺盐酸盐

An amino monosaccharide

GC46476 19S(20R)-EpDPA

19S,20R-EDP, 19S,20R-EpDPE, 19S,20R-epoxy DPA, 19S,20R-epoxy Docosapentaenoic Acid

A neuropeptide with diverse biological activities

GC46475 19R(20S)-EpDPA

19R,20S-epoxy Docosapentaenoic Acid, 19R,20S-epoxy DPA, 19R,20S-EDP, 19R,20S-EpDPE

A DHA metabolite

GC46471 17β-hydroxy Exemestane-d3 A neuropeptide with diverse biological activities

GC46470 17β-Estradiol-d2

BETA-雌二醇-D2,β-Estradiol-d2; 17β-Estradiol-d2; 17β-Oestradiol-d2

An internal standard for the quantification of 17β-estradiol

GC46464 17R(18S)-EpETE

17R,18S-EEQ, 17R,18S-epoxy Eicosatetraenoic Acid

An EPA metabolite and activator of K_Ca1.1/BK channels

GC46448 15-deoxy-δ12,14-Prostaglandin J2-d9

15d-PGJ2-d9; 15-Deoxy-Δ12,14-PGJ2-d9

A neuropeptide with diverse biological activities

GC46447 15-deoxy-δ12,14-Prostaglandin J2-d4

15d-PGJ2-d4; 15-Deoxy-Δ12,14-PGJ2-d4

An internal standard for the quantification of 15-deoxy-Δ^12,14-prostaglandin J₂

GC46444 15-deoxy-δ12,14-Prostaglandin D2-d9

15-deoxy-Δ12,14-PGD2-d9

A neuropeptide with diverse biological activities

GC46443 15-deoxy-δ12,14-Prostaglandin D2-d4

15-deoxy-Δ12,14-PGD2-d4

A neuropeptide with diverse biological activities

GC46438 14S(15R)-EET

14S,15R-EpETrE

A cytochrome P450 metabolite of arachidonic acid

GC46435 13-cis-Retinoic Acid-d5

Isotretinoin-d5

An internal standard for the quantification of 13-cis retinoic acid

GC46427 13,14-dihydro-15-keto Prostaglandin E2-d9

13,14-dihydro-15-keto PGE2-d9, 13,14-dihydro-oxo-PGE2-d9, PGEM-d9

A neuropeptide with diverse biological activities

GC46426 13,14-dihydro-15-keto Prostaglandin E2-d4

13,14-dh-15-keto PGE2-d4, 13,14-dihydro-oxo-PGE2-d4, PGEM-d4

A neuropeptide with diverse biological activities

GC46387 1,3,7-Trimethyluric Acid-d9

TMU-d9, 8-oxo Caffeine-d9

An internal standard for the quantification of 1,3,7-trimethyluric acid

GC46373 1,2,3-Triundecanoyl Glycerol

11碳酸三甘油酯

A triacylglycerol

GC46365 1,1'-(Azodicarbonyl)dipiperidine

偶氮二甲酰二哌啶

A Mitsunobu reagent

GC46352 (S)-DO271 An inactive control for DO264

GC46350 (S)-Bromoenol lactone-d7

(S)-BEL-d7; (S,E)-Bromoenol lactone-d7

A neuropeptide with diverse biological activities

GC46347 (S)-(+)-Methoprene

S-(+)-烯虫酯,(+)-Methoprene; (7S)-Methoprene

An insect growth regulator and Met agonist

GC46342 (R)-Bromoenol lactone-d7

(R)BELd7

A neuropeptide with diverse biological activities

GC46333 (4′-Hydroxy)phenoxybenzoic Acid

3-(4'-羟基)苯氧基苯甲酸

A pyrethroid insecticide metabolite

GC46332 (2S)-Octyl-α-hydroxyglutarate-d17

(2S)-Octyl-2-HG-d17

A neuropeptide with diverse biological activities

GC46330 (2R)-Octyl-α-hydroxyglutarate-d17

(2R)Octyl2-HG-d17

A neuropeptide with diverse biological activities

GC46314 (±)-β-Hydroxybutyrate-d4 (sodium salt)

β-Hydroxybutyric acid-d4 sodium

An internal standard for the quantification of (±)-β-hydroxybutyrate

GC46284 (±)-Cotinine-d3

氘代甲基可替宁,(±)-Cotinine-d3; (Rac)-NIH-10498-d3

An internal standard for the quantification of cotinine

GC46268 (±)9-HETE-d8

(±)9-Hydroxyeicosatetraenoic Acid-d8

A neuropeptide with diverse biological activities

GC46264 (±)8(9)-EET-d11

(±)8,9-EET-d11, (±)8,9-EpETrE-d11

A neuropeptide with diverse biological activities

GC46262 (±)5(6)-EET-d11

(±)5,6-EET-d11

A neuropeptide with diverse biological activities

GC46260 (±)17(18)-EpETE

(±)17,18-EEQ, (±)17,18-epoxy Eicosatetraenoic Acid

A neuropeptide with diverse biological activities

GC46257 (±)12(13)-EpOME-d4

(±)12,13-EODE-d4, Isoleukotoxin-d4, (±)Vernolic Acidd4

A neuropeptide with diverse biological activities

GC46256 (±)12(13)-DiHOME-d4

Isoleukotoxin diold4

A neuropeptide with diverse biological activities

GC61355 Tris(2,4-di-tert-butylphenyl)phosphate

三(2,4-二-叔丁基苯基)磷酸酯

Tris(2,4-di-tert-butylphenyl)phosphate是从VitexnegundoL.中分离的一种活性化合物，具有抗炎活性，并通过分子对接抑制了分泌性磷脂酶A2(sPLA2)。

GC61344 trans-Benzylideneacetone

亚苄基丙酮; trans-Benzalacetone

Trans-4-Phenyl-3-buten-2-one (trans-Benzylideneacetone, trans-Benzalacetone, trans-Benzylideneacetone) is an inhibitor of the enzyme phospholipase A2 (PLA2). Trans-4-Phenyl-3-buten-2-one is used as a flavouring agent, a fragrance and a bacterial metabolite.

GC61251 Rosuvastatin D3

ZD 4522 D3

RosuvastatinD3(ZD4522D3)是Rosuvastatin的一种氘代化合物。Rosuvastatin(ZD4522)是一种竞争性HMG-CoA还原酶抑制剂，IC50为11nM。Rosuvastatin有效阻断人类醚-a-go-go相关基因(hERG)电流，IC50为195nM，延迟心脏复极化，从而延长动作电位持续时间(APDs)和校正QT间期(QTc)间隔。

GC61191 Piperonylic acid

胡椒酸

Piperonylicacid是具有亚甲二氧基功能的天然分子，模拟反式肉桂酸的结构。Piperonylicacid是反式肉桂酸4-羟化酶的选择性的灭活剂。

GC61187 Pioglitazone D4

匹格列酮-D4,U 72107-d4

An internal standard for the quantification of pioglitazone

GC61155 Omeprazole sodium

奥美拉唑钠,H 16868 sodium

An irreversible inhibitor of the gastric proton pump

GC61055 Methyl oleanonate

3-Oxoolean-12-en-28-oic acid methyl ester

Methyloleanonate是从Pistacia中分离得到的三萜类PPARγ激动剂。Methyloleanonate是齐墩果酸衍生物，具有抗癌作用。

GC61043 Mesalamine impurity P

美沙拉嗪EP杂质P

MesalamineimpurityP是Mesalamine的杂质。5-Aminosalicylicacid(Mesalamine)是一种特异性的 PPARγ 激动剂，还抑制p21-激活激酶1(PAK1)和 NF-κB。

GC61040 Melittin TFA

蜂毒肽三氟乙酸盐；蜂毒素三氟乙酸盐

Melittin (MLT, Forapin, Forapine) is an activator of phospholipase A2 (PLA2) that stimulates the activity of the low molecular weight PLA2, while it does not the increase the activity of the high molecular weight enzyme.

GC60982 LEI-401 An NAPE-PLD inhibitor

GC60970 KY19382

A3051

KY19382 (A3051) is a Wnt/β-catenin signalling activator through inhibitory effects on both CXXC5–DVL interaction and GSK3β activity with IC50s of 19 nM and 10 nM, respectively.