Signaling Pathways

C-02是一种蛋白酶降解靶向嵌合物（PROTAC），由己糖激酶抑制剂洛尼达胺和小脑素配体沙利度胺组成。

福莫菌素B4（FB4）是一种霉菌毒素，已在垂直赤壳霉中发现。它也被发现存在于玉米和家禽饲料中。

Ipamorelin是一种五肽生长激素分泌素（GHS）和GHS受体1a（GHS-R1a）激动剂。

De-Boc-Cabazitaxel是半合成紫杉醇cabazitaxel商业制剂中的潜在杂质。它还被用于合成针对微管靶向荧光染料。

商业制备的可离子化阳离子氨基脂质ALC-0315中可能存在一种潜在杂质ALC-0315 N-oxide。

CYN 154806是一种环状肽类生长抑素受体2（SST2）拮抗剂（IC50 = 2.62 nM）。它对SST1、SST3、SST4和SST5具有选择性，而选择性较高的是对于SST2（分别为IC50s = 3,890、851、1,737和331 nM）。

Tat-Gap 19是一种连接蛋白43（Cx43）半通道的肽抑制剂。它由HIV-1 Tat蛋白转导域和与Cx43残基128-136相对应的九个氨基酸肽链组成。

Exendin-4 (3-39)酰胺是一种糖肽样肽1受体（GLP-1R）激动剂，也是exendin-4 (48-86)酰胺的活性代谢物。

DPPD-Q is an oxidized derivative of the antioxidant and substituted p-phenylenediamine DPPD.

Proxymetacaine is an anesthetic.

Chondroitin sulfate A (CSA) is a glycosaminoglycan.

Propiverine N-oxide is an active metabolite of the muscarinic acetylcholine receptor antagonist propiverine .

Semaglutide side chain is a synthetic intermediate.

6-Deoxy-8-O-methylrabelomycin is an anthraquinone that has been found in Pseudonocardia with antiparasitic and antibiotic activities.

EB 47 is an inhibitor of poly(ADP-ribose) polymerase 1 (PARP1; IC50 = 45 nM) and a dual site inhibitor of tankyrase 2 (TNKS2; IC50 = 45 nM).

Voriconazole-d3 N-oxide is intended for use as an internal standard for the quantification of voriconazole N-oxide by GC- or LC-MS.

Bayer 18 is a tyrosine kinase 2 (TYK2) inhibitor (IC50 = 18.7 nM).

CP 93,129 is an agonist of the serotonin (5-HT) receptor subtype 5-HT1B.

para-methoxy-2-amino-Benzamidoxime (PMA) is a fluorescent and reactive probe for ketones.

β-Ionone acid is the acid form of the β-carotenoid derivative β-ionone.

DTPD is a substituted p-phenylenediamine and non-oxidized version of DTPD-Q .

5-Acetamide-butenolide is a mycotoxin that has been found in Fusarium and has pro-oxidant activity.

(E/Z)-Droloxifene is a mixture of (E)-droloxifene, a selective estrogen receptor modulator (SERM), and (Z)-droloxifene.

Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH is a building block in the synthesis of the glucagon-like peptide 1 receptor (GLP-1R) agonist semaglutide .