Metabolism
Metabolism(代谢)
- PPAR(219)
- 5-alpha Reductase(11)
- 5-Lipoxygenase(11)
- Adenosine Deaminase(10)
- Aminopeptidase(15)
- C14ɑ demethylase(2)
- Carbonic Anhydrase(55)
- CETP(9)
- Cholesterol absorption(1)
- CPT1(2)
- CYP3A/CYP450(22)
- Dehydrogenase(43)
- DHFR(7)
- DGAT(10)
- Dopamine β-hydroxylase(10)
- Enolase(5)
- FAAH(38)
- Factor Xa(61)
- Ferroptosis(198)
- Folate Analogue(2)
- Glucokinase(18)
- HLE(1)
- HMG-CoA Reductase(37)
- HSP(100)
- IDO(46)
- KRAS-PDEδ(3)
- MAO(6)
- Metabolic Enzymes(6)
- Neuronal Metabolism(8)
- Oxidative Phosphorylation(26)
- P450(456)
- PDE(250)
- Phospholipase(130)
- Procollagen C Proteinase(1)
- Saccharometabolism(1)
- SCD(20)
- SGLT(29)
- TPH(4)
- Transferase(26)
- Energy Metabolism
- Inorganic Ions
- ALP(1)
- Carbohydrates(36)
- Uric Acid
- Muscle Metabolism
- MDA
- MPO
- Transaminase(3)
- Glutathione Reductase(1)
- Thioredoxin Reductase
- Catalase(15)
- monooxygenase(1)
- PKM2(1)
- Aldehyde dehydrogenase(1)
- Squalene synthase(1)
- Hydrolase(17)
- ornithine decarboxylase(1)
- Amino acid metabolism(3)
- phosphatases(103)
- Pyruvate kinase(13)
- Others(64)
- MGL(1)
- Galactosidase(2)
- 12-Lipoxygenase(1)
- Fatty Acid Synthase (FASN)(9)
- Dihydroorotate Dehydrogenase(13)
- Bile Acids & Microbiome(131)
- Bone Growth & Remodeling(55)
- Carbohydrate Metabolism(166)
- Cofactors & Vitamins(87)
- Dyslipidemias(109)
- Inborn Errors of Metabolism(100)
- Metabolic Syndrome(22)
- Necroptosis(12)
- Necrosis(19)
- Nutrient Sensing(14)
- Phosphodiesterase(34)
- Reproductive Biology(184)
- Thermogenesis(10)
- Sterol Biosynthesis(42)
- Prolyl Hydroxylation Enzymes(2)
- Biliary System(16)
- Metabolic Disease(5)
- Fat Mass and Obesity-associated Protein (FTO)(5)
- SHIP(1)
- FOXO
- Furin(1)
- Liposome(8)
- MetAP
- PGC-1α
- PI5P4K(1)
- Metabolic Diseases(2)
Metabolism 相关产品(3072)
- GC15222Siramesine hydrochlorideCAS: 224177-60-0纯度: >99.50%
Siramesine hydrochloride是一种有效的sigma-2受体激动剂。Siramesine对sigma-2受体具有亚纳摩尔亲和力 (IC 50 =0.12nM)，并且对sigma-2受体的选择性是sigma-1受体的140倍(IC 50 =17nM)。
- GC15231Oleoyl Ethyl AmideCAS: 85075-82-7纯度: >98.00%
An endocannabinoid analog that inhibits FAAH and has analgesic activity
- GC15356Prion Protein 106-126 (human)CAS: 148439-49-0
PrP(106-126)是与朊病毒蛋白的淀粉样区域相对应的多肽段，它的生化特性类似于朊病毒蛋白的感染区域。
- GC15442Tipifarnib (Zarnestra)CAS: 192185-72-1纯度: >98.50%
A farnesyltransferase inhibitor with antitumor activity
- GC15530DapagliflozinCAS: 461432-26-8纯度: >99.50% / >98.00%
Dapagliflozin 是一种钠-葡萄糖协同转运蛋白 2 (SGLT2) 抑制剂，是一种新型抗糖尿病药物，由于其抑制 SGLT2 介导的肾葡萄糖重吸收的能力而被批准用于治疗 T2DM。
- GC15577Bestatin hydrochlorideCAS: 65391-42-6纯度: >99.50% / >99.00%
Bestatin hydrochloride是氨基肽酶N（APN/CD13）抑制剂，其IC 50 值为14.9±3.4μM。
- GC15681Liproxstatin-1CAS: 950455-15-9纯度: >98.00%
Liproxstatin-1 是一种有效的铁死亡抑制剂，可以防止铁死亡诱导剂，例如丁硫氨酸亚砜胺 (BSO)、erastin 和 (1S,3R)-RSL3 (RSL3)。
- GC15736Rosuvastatin CalciumCAS: 147098-20-2纯度: >99.50%
Rosuvastatin Calcium是一种竞争性HMG-CoA还原酶抑制剂，IC 50 值为11nM。
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC15158 | Tioxolone | 4991-65-5 | >98.50% | |
A carbonic anhydrase I inhibitor | ||||
| GC15209 | WWL123 | 1338575-41-9 | - | |
A selective inhibitor of ABHD6 | ||||
| GC15210 | PF-622 | 898235-65-9 | - | |
A selective, potent FAAH inhibitor | ||||
| GC15222 | Siramesine hydrochloride | 224177-60-0 | >99.50% | |
Siramesine hydrochloride是一种有效的sigma-2受体激动剂。Siramesine对sigma-2受体具有亚纳摩尔亲和力 (IC 50 =0.12nM)，并且对sigma-2受体的选择性是sigma-1受体的140倍(IC 50 =17nM)。 | ||||
| GC15231 | Oleoyl Ethyl Amide | 85075-82-7 | >98.00% | |
An endocannabinoid analog that inhibits FAAH and has analgesic activity | ||||
| GC15242 | Vardenafil | 224785-90-4 | - | |
Vardenafil 是一种具有口服活性的选择性磷酸二酯酶 5 (PDE5) 抑制剂，IC50 为 0.7 nM。 | ||||
| GC15244 | Thienyldecyl Isothiocyanate | 288323-41-1 | - | |
An antiproliferative isothiocyanate | ||||
| GC15257 | Perhexiline (maleate) | 6724-53-4 | >98.00% | |
Inhibitor of carnitine palmitoyltransferases | ||||
| GC15266 | Qc 1 | 403718-45-6 | >98.00% | |
Qc 1 是一种可逆的非竞争性苏氨酸脱氢酶 (TDH) 抑制剂。 | ||||
| GC15286 | Dimethyl DL-Glutamate (hydrochloride) | 13515-99-6 | - | |
A cell-permeant glutamate derivative | ||||
| GC15344 | SP 600125 | 129-56-6 | >98.00% | |
SP 600125是一种具有口服活性的、可逆的、具有选择性的ATP竞争性JNK 抑制剂，对JNK1、JNK2和JNK3的IC 50 分别为40、40和90nM。SP 600125常用于卵巢癌、肿瘤、帕金森病 (PD)、乳腺癌和哮喘的研究。 | ||||
| GC15356 | Prion Protein 106-126 (human) | 148439-49-0 | - | |
PrP(106-126)是与朊病毒蛋白的淀粉样区域相对应的多肽段，它的生化特性类似于朊病毒蛋白的感染区域。 | ||||
| GC15387 | TPPU | 1222780-33-7 | >99.00% / >98.00% | |
TPPU是一种可溶性环氧化物水解酶(sEH)抑制剂，对猴和人sEH的IC50值分别为37和3.7 nM。 | ||||
| GC15399 | Dp44mT | 152095-12-0 | >98.00% | |
An iron chelator with antiproliferative effects | ||||
| GC15442 | Tipifarnib (Zarnestra) | 192185-72-1 | >98.50% | |
A farnesyltransferase inhibitor with antitumor activity | ||||
| GC15445 | TMS | 24144-92-1 | >99.00% / >98.00% | |
TMS（2,3',4,5'-tetramethoxystilbene）是一种特异性强效的CYP1B1抑制剂，IC 50 值为6±2nmol/L。 | ||||
| GC15530 | Dapagliflozin | 461432-26-8 | >99.50% / >98.00% | |
Dapagliflozin 是一种钠-葡萄糖协同转运蛋白 2 (SGLT2) 抑制剂，是一种新型抗糖尿病药物，由于其抑制 SGLT2 介导的肾葡萄糖重吸收的能力而被批准用于治疗 T2DM。 | ||||
| GC15547 | Inosine-5'-monophosphate (sodium salt hydrate) | 20813-76-7 | - | |
A 5’-ribonucleoside | ||||
| GC15577 | Bestatin hydrochloride | 65391-42-6 | >99.50% / >99.00% | |
Bestatin hydrochloride是氨基肽酶N（APN/CD13）抑制剂，其IC 50 值为14.9±3.4μM。 | ||||
| GC15601 | AG-120 | 1448347-49-6 | >99.50% / >98.00% | |
AG-120 (Ivosidenib)是一种突变型异柠檬酸脱氢酶1（mIDH1）抑制剂。 | ||||
| GC15673 | CP 775146 | 702680-17-9 | - | |
A PPARα agonist | ||||
| GC15681 | Liproxstatin-1 | 950455-15-9 | >98.00% | |
Liproxstatin-1 是一种有效的铁死亡抑制剂，可以防止铁死亡诱导剂，例如丁硫氨酸亚砜胺 (BSO)、erastin 和 (1S,3R)-RSL3 (RSL3)。 | ||||
| GC15736 | Rosuvastatin Calcium | 147098-20-2 | >99.50% | |
Rosuvastatin Calcium是一种竞争性HMG-CoA还原酶抑制剂，IC 50 值为11nM。 | ||||
| GC15738 | BVT 2733 | 376640-41-4 | >98.00% | |
An 11β-HSD1 inhibitor | ||||