Membrane Transporter/Ion Channel
Membrane Transporter/Ion Channel(跨膜转运)
- AMPAR(58)
- ATPase(80)
- Calcium Channel(331)
- Cannabinoid Transporters(6)
- CFTR(45)
- Chloride Channels(13)
- GABA Receptor(239)
- Gardos Channel(1)
- Glucose Transporters(13)
- Glutamate (EAAT) Transporters(18)
- Glycine Receptors(2)
- GlyT(19)
- GTPase(32)
- Kv1.3(1)
- ICB(2)
- Lipophilic platinum complex(1)
- M2 ion Channel(1)
- MCT2(2)
- Monoamine transporter(18)
- Monocarboxylate Transporters(12)
- Multidrug Transporters(4)
- Na+/Ca2+ Exchanger(16)
- NKCC(7)
- NMDA Receptor(81)
- Nucleoside Transporters(4)
- Pannexin-1(2)
- P2X purinergic receptor(68)
- P-gp(11)
- Proton Pump(56)
- Potassium Channel(308)
- Sodium Channel(211)
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- MCT(3)
- Kainate Receptors(12)
- Ionophore(3)
- sodium-hydrogen exchanger(3)
- Chloride Channel(27)
- CRAC Channel(13)
- EAAT2(6)
- HCN Channel(6)
- Na+/HCO3- Cotransporter(1)
- Na+/K+ ATPase(28)
- P-glycoprotein(49)
- iGluR(164)
- nAChR(103)
- VDAC(2)
- Aquaporins(1)
- Piezo Channels(1)
- GlyR(1)
- Ferroportin(1)
- Urea Transporter(1)
- Na+/H+ Exchanger (NHE)(1)
- NTPDase(1)
- EAAT(1)
- Piezo Channel(1)
- ASCT(2)
Membrane Transporter/Ion Channel 相关产品(2265)
- GC32673Almokalant (H 234/09)CAS: 123955-10-2
Almokalant (H 234/09) 是一种 III 类抗心律失常药物，作为钾通道阻滞剂，可抑制时间依赖性延迟整流器 K+ 电流的特定成分 (Ikr)。
- GC32849Pico145 (HC-608)CAS: 1628287-16-0纯度: >98.50%
Pico145 (HC-608)是一种TRPC1/4/5通道抑制剂，可抑制(-)-englerin A激活的TRPC4/TRPC5通道，IC 50 值分别为0.349nM和1.3nM。
- GC33003Daurisoline ((R,R)-Daurisoline)CAS: 70553-76-3纯度: >99.50%
An alkaloid with diverse biological activities
- GC33185Encequidar mesylate (HM30181 (mesylate))CAS: 849675-87-2纯度: >98.00%
HM30181 mesylate salt, a tetrazole derivative, is known as a P-glycoprotein inhibitor that has inhibitory activities on multidrug resistance in cancer cells.
- GC33338Biricodar (VX-710)CAS: 159997-94-1
Biricodar (VX-710) (VX-710) 是 P-糖蛋白和 MRP-1 的调节剂；在多重耐药细胞中显示出有效的化学增敏活性。
- GC33341Transcrocetin (trans-Crocetin)CAS: 27876-94-4纯度: >98.00%
A natural apocarotenoid with diverse biological activities
- GC33458Trimethadione (3,5,5,-Trimethyloxazolidine-2,4-dione)CAS: 127-48-0纯度: >98.00%
An anticonvulsant
- GC33486DehydronitrosonisoldipineCAS: 87375-91-5纯度: >98.00% / >99.50%
Dehydronitrosonisoldipine是尼索地平（Nisoldipine）的衍生物，在保留钙离子通道拮抗活性的同时，还具备抑制无菌α和TIR基序蛋白1（SARM1）的功能，因而成为一种双重生物活性化合物。
- GC33492Rapastinel Trifluoroacetate (GLYX-13 Trifluoroacetate)CAS: 1435786-04-1纯度: >98.00%
A partial agonist of the NMDA receptor
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC32673 | Almokalant (H 234/09) | 123955-10-2 | - | |
Almokalant (H 234/09) 是一种 III 类抗心律失常药物，作为钾通道阻滞剂，可抑制时间依赖性延迟整流器 K+ 电流的特定成分 (Ikr)。 | ||||
| GC32755 | DNQX (FG 9041) | 2379-57-9 | >98.00% | |
A non- NMDA glutamate receptor antagonist | ||||
| GC32849 | Pico145 (HC-608) | 1628287-16-0 | >98.50% | |
Pico145 (HC-608)是一种TRPC1/4/5通道抑制剂，可抑制(-)-englerin A激活的TRPC4/TRPC5通道，IC 50 值分别为0.349nM和1.3nM。 | ||||
| GC32906 | Sinapine | 18696-26-9 | >99.50% | |
Sinapine is an alkaloid isolated from seeds of the cruciferous species with antioxidant, antitumor and radio-protective activities. Sinapine inhibits the proliferation of Caco-2 cells via downregulation of P-glycoprotein. | ||||
| GC32924 | Linaprazan (AZD0865) | 248919-64-4 | >98.50% | |
An H + /K + -ATPase inhibitor | ||||
| GC32961 | D-3263 hydrochloride | 1008763-54-9 | >98.00% | |
D-3263hydrochloride是一种可口服的TRPM8激动剂。 | ||||
| GC33003 | Daurisoline ((R,R)-Daurisoline) | 70553-76-3 | >99.50% | |
An alkaloid with diverse biological activities | ||||
| GC33024 | Chlorotoxin | 163515-35-3 | >98.00% | |
Chlorotoxin是一种从以色列杀人蝎毒液中分离的多肽毒素。 | ||||
| GC33151 | Polyoxyethylene stearate (POES) | 9004-99-3 | - | |
聚氧乙烯硬脂酸酯（POES）（POES）是一种非离子型乳化剂。 | ||||
| GC33158 | D-3263 | 947257-66-1 | - | |
D-3263是一种有效的TRPM8激动剂，具有抗肿瘤活性。 | ||||
| GC33176 | Teludipine hydrochloride (GR53992B) | 108700-03-4 | - | |
特鲁地平是一种亲脂性钙通道阻滞剂。 | ||||
| GC33185 | Encequidar mesylate (HM30181 (mesylate)) | 849675-87-2 | >98.00% | |
HM30181 mesylate salt, a tetrazole derivative, is known as a P-glycoprotein inhibitor that has inhibitory activities on multidrug resistance in cancer cells. | ||||
| GC33234 | Gboxin | 2101315-36-8 | >99.00% / >98.00% | |
Gboxin是癌细胞中氧化磷酸化（OXPHOS）的抑制剂，能够靶向抑制胶质母细胞瘤（GBM）。 | ||||
| GC33338 | Biricodar (VX-710) | 159997-94-1 | - | |
Biricodar (VX-710) (VX-710) 是 P-糖蛋白和 MRP-1 的调节剂；在多重耐药细胞中显示出有效的化学增敏活性。 | ||||
| GC33341 | Transcrocetin (trans-Crocetin) | 27876-94-4 | >98.00% | |
A natural apocarotenoid with diverse biological activities | ||||
| GC33375 | MCI826 | 140646-80-6 | - | |
MCI826是一种P-glycoprotein(P-gp)拮抗剂。 | ||||
| GC33423 | JT010 | 917562-33-5 | >98.00% | |
A TRPA1 channel agonist | ||||
| GC33424 | SAR7334 | 1333210-07-3 | >99.50% | |
SAR7334是一种高效的TRPC6通道特异性抑制剂（IC 50 =7.9nM）。 | ||||
| GC33443 | Pyr6 | 245747-08-4 | >99.00% | |
Pyr6 是 TRPC3 的选择性抑制剂，IC50 为 0.49 uM（在 thapsigargin 耗尽的天然 RBL-2H3 细胞中，Ca2+ 流入抑制）。 | ||||
| GC33458 | Trimethadione (3,5,5,-Trimethyloxazolidine-2,4-dione) | 127-48-0 | >98.00% | |
An anticonvulsant | ||||
| GC33472 | Synta66 | 835904-51-3 | >99.00% | |
Synta66是钙离子通道Orai(CRAC的核心)的抑制剂，主要用于神经疾病的研究。 | ||||
| GC33486 | Dehydronitrosonisoldipine | 87375-91-5 | >98.00% / >99.50% | |
Dehydronitrosonisoldipine是尼索地平（Nisoldipine）的衍生物，在保留钙离子通道拮抗活性的同时，还具备抑制无菌α和TIR基序蛋白1（SARM1）的功能，因而成为一种双重生物活性化合物。 | ||||
| GC33492 | Rapastinel Trifluoroacetate (GLYX-13 Trifluoroacetate) | 1435786-04-1 | >98.00% | |
A partial agonist of the NMDA receptor | ||||
| GC33504 | 4-Acetamidobutanoic acid (N-acetyl GABA) | 3025-96-5 | >98.00% | |
A GABA derivative | ||||