TRPV1
TRPV1 (transient receptor potential vanilloid 1) is a calcium permeant cation channel that detects thermal stimuli and noxious chemical. It is a drug target for analgesics.
TRPV1 相关产品(10)
| 货号 | 产品名称 | CAS号 | 纯度 | 结构 |
|---|---|---|---|---|
| GC13003 | AMG-517 | 659730-32-2 | >99.50% | |
A TRPV1 antagonist | ||||
| GC14580 | SB705498 | 501951-42-4 | >99.50% | |
SB705498是一种口服生物可利用的、竞争性的辣椒素介导的 TRPV1 受体拮抗剂（人类、大鼠和豚鼠的pKis分别为7.6、7.5和7.3）。SB705498能够快速、可逆地抑制辣椒素、酸或热介导的人类TRPV1激活。 | ||||
| GC17918 | Capsazepine | 138977-28-3 | >99.00% | |
Capsazepine是瞬时受体电位香草素1（TRPV1）受体的特异性拮抗剂，IC 50 值为562 nM。 | ||||
| GC11147 | Oleoyl Serotonin | 1002100-44-8 | - | |
TRPV1 antagonist | ||||
| GC12097 | Palmitoyl Serotonin | 212707-51-2 | >98.00% | |
Potential TRPV1 antagonist | ||||
| GC12636 | Capsiconiate | 946572-73-2 | - | |
A partial agonist of TRPV1 | ||||
| GC12772 | Eicosapentaenoyl Serotonin | 199875-71-3 | - | |
A potential TRPV1 antagonist | ||||
| GC14761 | Mavatrep | 956274-94-5 | >99.50% | |
Mavatrep (JNJ-39439335) 是一种具有口服活性、选择性和有效的 TRPV1 拮抗剂，对 hTRPV1 通道具有高亲和力 (Ki=6.5 nM)。 | ||||
| GC15580 | Stearoyl Serotonin | 67964-87-8 | - | |
Potential TRPV1 antagonist | ||||
| GC16627 | Docosahexaenoyl Serotonin | 283601-58-1 | - | |
Potential TRPV1 antagonist | ||||