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Home >> Signaling Pathways >> Membrane Transporter/Ion Channel >> ATPase

ATPase(ATP酶)

ATPase is a class of enzymes that catalyze the decomposition of ATP into ADP and a free phosphate ion, including some co-transporters and pumps.

Products for  ATPase

  1. Cat.No. 产品名称 Information
  2. GC40434 (±)16-HETE

    (±)16-Hydroxyeicosatetraenoic Acid

     A potent inhibitor of proximal tubule ATPase activity
  3. GC13430 (-)-Blebbistatin

    (S)-(-)-Blebbistatin

     (-)-Blebbistatin是外消旋体混合物(±)-Blebbistatin（货号：GC12341）的一种其中一个构型，是活性形式。(-)-Blebbistatin是一种非肌肉肌球蛋白II ATP酶的细胞渗透性抑制剂，有效抑制多种横纹肌肌球蛋白以及脊椎动物非肌肉肌球蛋白，IC50值范围为0.5-5μM，平滑肌肌球蛋白仅受到微弱抑制（IC50=80μM）。
  4. GC41719 (R)-nitro-Blebbistatin

    R(-)7Desmethyl8nitro Blebbistatin

     A more stable form of (+)-blebbistatin
  5. GC41557 (S)-3'-amino Blebbistatin

    (-)-3'-amino Blebbistatin, m-amino Blebbistatin, meta-amino Blebbistatin

     A more stable form of (–)-blebbistatin
  6. GC41484 (S)-3'-hydroxy Blebbistatin

    (-)-3'-hydroxy Blebbistatin, meta-hydroxy-Blebbistatin, m-hydroxy-Blebbistatin

     A more stable form of (–)-blebbistatin
  7. GC41091 (S)-Lansoprazole

    左旋兰索拉唑

     A proton pump inhibitor
  8. GC41739 (S)-nitro-Blebbistatin

    S(-)7Desmethyl8nitro Blebbistatin

     A more stable form of (–)-blebbistatin
  9. GC46047 14-Anhydrodigitoxigenin A cardenolide
  10. GC40453 16(R)-HETE

    16(R)-Hydroxyeicosatetraenoic Acid

     A potent vasodilator
  11. GC40454 16(S)-HETE

    16(S)-Hydroxyeicosatetraenoic Acid

     A potent inhibitor of proximal tubule ATPase activity
  12. GC40455 17(R)-HETE

    17(R)-Hydroxyeicosatetraenoic Acid

     An inactive isomer of 17-HETE
  13. GC40456 17(S)-HETE

    17(S)-Hydroxyeicosatetraenoic Acid

     A potent inhibitor of proximal tubule ATPase activity
  14. GC12469 2,3-Butanedione-2-monoxime

    2,3-丁烷二酮一肟,BDM|Diacetyl Monoxime|NSC 660|NSC 116103

     A non-selective myosin ATPase inhibitor
  15. GC49575 4-hydroxy Omeprazole sulfide

    埃索美拉唑有关物质

     A metabolite of omeprazole
  16. GC18474 Acetyldigitoxin

    乙酰洋地黄毒甙; Digitoxin 3'''-Acetate

     An Na+/K+ ATPase inhibitor
  17. GC46841 Amiloride (hydrochloride) (hydrate)

    MK-870

     具有多种生物活性的神经肽
  18. GC42827 Apoptolidin

    Apoptolidin A

     An apoptosis inducer and F1FO ATPase inhibitor
  19. GC17225 ARL 67156 trisodium salt

    FPL 67156 trisodium

     ARL67156 (FPL 67156) trisodium 是一种选择性 ecto-ATPase 抑制剂。
  20. GC35421 ATP synthase inhibitor 1 ATP synthase inhibitor 1 是一种 F1/FO-ATP 合酶复合物 c 亚基的有效抑制剂，抑制线粒体通透性转换孔的开放，但不影响 ATP 的水平。
  21. GC10934 Bafilomycin C1

    巴菲霉素C1

     A fungal metabolite with diverse biological activities
  22. GC12302 Bafilomycin D

    巴佛洛霉素D

     A fungal metabolite with diverse biological activities
  23. GC14664 BHQ

    2,5-二特丁基对苯二酚

     间接食品添加剂 BHQ (DTBHQ) 调节 5-脂氧合酶的活性以及 COX-2 的活性（IC50=1.8 和 14.1 ⋼；M 分别代表 5-LO 和 COX-2）。
  24. GC42965 Bongkrekic Acid

    米酵菌酸,Bongkrek Acid

    An inhibitor of mitochondrial adenine nucleotide translocase
  25. GC17683 Brefeldin A

    布雷非德菌素 A; BFA; Cyanein; Decumbin

     Brefeldin A（BFA）是一种真菌大环内酯，能够有效、可逆地抑制内质网和高尔基体之间的蛋白质运输和囊泡形成。
  26. GC16833 BTB06584

    BTB

     A mitochondrial F1FO-ATPase inhibitor
  27. GC47021 Caloxin 2A1 (trifluoroacetate salt)

    VSNSNWPSFPSSGGG-NH2

     A neuropeptide with diverse biological activities
  28. GC49706 Cerberin

    海果苷

     A cardiac glycoside with cytotoxic and cardiac modulatory activities
  29. GC11120 Ciclopirox ethanolamine

    环吡酮乙醇胺盐; Ciclopirox ethanolamine; HOE 296

     An iron chelator, antifungal, and anticancer agent
  30. GC10268 Cyclopiazonic acid

    环匹阿尼酸,NSC 117181

     A mycotoxin and SERCA inhibitor
  31. GC47149 Cyclopiazonic Acid-13C20

    CPA-13C20

     A neuropeptide with diverse biological activities
  32. GC18583 D-α-Hydroxyglutaric Acid

    R-2-羟基戊二酸,(R)-2-Hydroxyglutarate; (R)-2-Hydroxyglutaric acid; (R)-2-Hydroxypentanedioic acid

     D-α-Hydroxyglutaric Acid是α-酮戊二酸（α-KG）的弱竞争性拮抗剂（Ki = 10.87mM）。
  33. GC43412 Desacetyl Bisacodyl

    苉可硫酸钠杂质B

     An active metabolite of the laxatives bisacodyl and sodium picosulfate
  34. GC13108 Digoxin

    地高辛,12β-Hydroxydigitoxin

     地高辛（Digoxin）是一种强效的Na+/K+-ATP酶抑制剂，临床用于治疗心律失常和心力衰竭。
  35. GC43565 Doxorubicinol (hydrochloride)

    13-Dihydroadriamycin hydrochloride

     A doxorubicin metabolite
  36. GC10395 Dynasore Dynasore 作为 GTPase 抑制剂，可以快速、可逆地抑制发动蛋白活性，从而阻止内吞作用。
  37. GC18105 Enterostatin

    人肠抑素

     A pentapeptide involved in the regulation of food intake
  38. GC48984 Esomeprazole

    埃索美拉唑镁,(S)-Omeprazole; (-)-Omeprazole

     An H+/K+-ATPase inhibitor
  39. GC33234 Gboxin Gboxin是癌细胞中氧化磷酸化（OXPHOS）的抑制剂，能够靶向抑制胶质母细胞瘤（GBM）。
  40. GC16585 Golgicide A

    GCA

     A reversible inhibitor of GBF1
  41. GC71972 Isofalcarintriol Isofalcarintriol是线粒体ATP合酶的NRF2激活剂和选择性抑制剂。
  42. GC11448 Istaroxime

    PST-2744;PST 2744;PST2744

     Istaroxime (PST2744) 是一种有效的 Na+,K+-ATPase 抑制剂，IC50 为 0.11 μM。
  43. GC17786 Istaroxime hydrochloride

    ISTAROXIME盐酸盐,PST-2744 (hydrochloride);PST 2744 (hydrochloride);PST2744 (hydrochloride)

     Istaroxime hydrochloride 是 Na+/K+-ATPase 抑制剂 (IC50=0.11 μM) 和肌质/内质网钙 ATPase 2 (SERCA 2) 激活剂。
  44. GC16167 K 858 An inhibitor of Eg5
  45. GC47532 KUS121 A VCP modulator
  46. GC49640 Lansoprazole N-oxide

    2-[[[3-甲基-1-氧代-4-(2,2,2-三氟乙氧基)-2-吡啶]甲基]亚硫酰基]苯并咪唑

     A potential impurity found in bulk preparations of lansoprazole
  47. GC11254 Lithium carbonate

    碳酸锂

     Na+/K+ ATPase pump inhibitor
  48. GC14059 ML 240 A selective inhibitor of the ATPase p97
  49. GC11411 ML-7 hydrochloride

    1-(5-碘萘-1-磺酰基)-1H-六氢-1,4-二氮杂卓盐酸盐,ML 7 hydrochloride

     ML-7 hydrochloride是一种选择性肌球蛋白轻链激酶（IC50 = 300nM）。
  50. GC15858 MYK-461

    玛伐凯泰,MYK461; SAR439152

     A cardiac myosin ATPase inhibitor
  51. GC11587 Ochratoxin A

    赭曲霉素,Phe-OTA

    A mycotoxin

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